The MW should average 22131.00 and this does not. This would have to be explained to any approval board for LEGIT rHGH.
It's important to know when we are evaluating complex proteins such as GH by MS, what is being evaluated is the AVERAGE MW and bc the MW is so HIGH small differences in a compounds structure, although important from a clinical perspective, are easily overlooked, or AVERAGED.
Thus a compound like this can have several GH molecules with a plus one or two AA residues and several more with a minus one or two AA residues
And it's this minor variance in MW that can cause allergic reactions in some folk.
This is what's lacking in generic GH, a consistent product with adverse reactions that parallel ph grade rHGH and are equally biologically effective.
The latter is best determined by IGF levels as you suggest INH
It's important to know when we are evaluating complex proteins such as GH by MS, what is being evaluated is the AVERAGE MW and bc the MW is so HIGH small differences in a compounds structure, although important from a clinical perspective, are easily overlooked, or AVERAGED.
Thus a compound like this can have several GH molecules with a plus one or two AA residues and several more with a minus one or two AA residues
And it's this minor variance in MW that can cause allergic reactions in some folk.
This is what's lacking in generic GH, a consistent product with adverse reactions that parallel ph grade rHGH and are equally biologically effective.
The latter is best determined by IGF levels as you suggest INH
