MESO-Rx

Anabolic Steroids

MALDI-TOF-MS/HPLC-UV-VIS rHGH results

Would like to see pharmacom get into your que. Frank was talking like the next coming of Karl about their GH but he actually knew what lab tests to perform as well as the desired results expected from said labs. It's getting buried but can still be found in the basicstero thread.

Surprised DJ never chimed in but I supposed he is busy these days to mind source threads.
 
mands said:
I have not tested the hyges. You are more than welcome to send a vial though ;)

Yes glad to be working with him. And I will have some pharm grade Genos soon. Or supposed pharm grade lol

mands
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Hey bro I saw that you said you would test a vial of hyge if sent to you. I have a newer Chinese generic I just started about 3 weeks ago. Would you be willing to test it if I send you a vial? Thanks
 
Interested in testing the HGH from pharmacom. I'm from EU, I don't think I can send a vial to you in USA, but maybe we can buy ONE vial from darius or some other and get it shipped to you. would you do it?
 
Pharmacom Labs said:
Sorry for delayed reply. I asked our technologist to provide me the technical background & test results and was waiting till I get them to furnish my explanation with proofs. All this chemical things... It is a bit difficult again, I try to transmit this Info how I understood it in simple words.

I start from afar. Human growth hormone (HGH) is a polypeptide hormone. There are differents isoforms of HGH. The human body has 5 genes responsible for production of HGH by our body. They all are located in the 17th chromosome. But they are responsible for production of different types (isoforms) of HGH. The main isoform is a "full-value" growth hormone consisting of 191 amino-acid residues. It has the molecular weight 22127 amu (22 kDA). (This value is very important, because we use it in our tests to find proper raw materials. I explain later). It is synthesized and secreted by the anterior pituatary gland. However, for example one of the genes is responsible for producing another isoform of HGH by a women placenta as example. And this growth hormone is chemically different, another isoform. Generally in our blood stream can be found several types of HGH (at least 5 isoforms). However only one of them is a full-value HGH with 191 amino-acid residues. Its chemical formula is C990 H1532 N262 O300 S7. And this form is the main form which can be found in our blood. The second isoform which can be found in blood has molecular weight of only 20 kDA. In this form are missing amino-acid residues from 32 to 46, that is why the molecular weight is less. There are also shorter forms of HGH with less molecular value. You will see in the attached file the description of each isoform, the number of residues and molecular weights of each isoform.

By the way, I am sure you heard about different peptides which become popular now, they are a part of this complex structure, for example HGH Fragment 176-191, which consist only of indicated residues.

So...cbass00, while replying your question I say you are right, the most sources sell crap and you will see it in the results attached. Lot of manufacturers buy raw materials and sell HGH under their own brand. At this the most factories producing HGH are located in China. This is the same situation as with sport nutrition. There are only several factories, which produce raw materials for BCAA, different acids, etc. And they all are in China. Most of brands buy the powder, add aromatics and resell the products under their own brand.

Well, if you ask me, whether we produce HGH ourselves or use "chinese crap", I reply that we do not produce HGH ourselves and buy raws from Chinese manufacturers. BUT: what we buy is for sure not crap. We tested lot of raw material manufacturers and the results are attached. Last time we had kind of a "call for tenders" between HGH manufacturers in the beginning 2014. Our employee made anonymous small orders at the main manufacturers available in China and we tested the samples. By the way, we included into the tests also the most famous brands of growth hormone Kingtropin and Jintropin, which were bought anonymously from resellers. These are samples Nr. 4,11 and 12 in our tests. These were samples bought not as raw material, but as final products, in packages, at retail price, etc. As you will be able too see both of them did not consist any HGH at all... Famous brand means not always quality guarantee as you can see. I guess that were fakes, because we bought them not directly from manufacturers, but anonymously at resellers. Other samples we bought as raw material directly from manufacturers, had HGH, but not all of them as well. Sample 2 and sample 5 were not HGH. Only 7 of 12 tested powders were HGH.

However, this is not the end of the story. As you can see in results, 3 of 7 HGH samples had not the "full-value" HGH with 191 amino-acid recidues and molecular weight 22 kDA, but that were "cut" isoforms of HGH with the molecular weight about 17 kDA and only 153 amino acid residues. Lot of manufacturers produce not full-value HGH and sell it as a growth hormone. Only 4 of 12 examined samples had real full-valued HGH with 191 residues.

This is also not the end of the story... the quality can be good, but there is also the question about the weight content of HGH. We took the same amount of the powder from each sample and performed the tests and found out that samples have different amount of HGH itself. You can see the values in mg in the file attached.

Conclusion:
When we chose suppliers of raw materials for HGH we:
1. Work only with suppliers offering the full-value HGH with 191 amino-acid residues. This is very important for the efficiency of HGH. I just provide the first scientific article I found to this topic:
Code: 
http://www.ncbi.nlm.nih.gov/pubmed/11720906
You can read there one simple sentence: The 20 kDa form has been reported to have weaker diabetogenic and lipolytic actions than the 22 kDa form. And the shorter form are even weaker.
2. In addition to the that we control also the weight content of HGH in the powder.
Guys you can see, that we totally examined the samples and used several testing methods: electron spectroscopy, mass spectrometry and PAGE (polyacrylamide gel electrophoresis). So we are absolutely sure in the results.
If you buy our HGH you can be sure that this is full-value HGH and each vial has the manifested 10 IU.

p.s. Probably someone will ask, why the test result is so old. I reply. As I said, it was the last result when we organized a "call for tenders" and chose one of several raws suppliers. We chose one supplier and now there is no need to check other suppliers. We buy big batches of raws from this only supplier, perform the chromatographic analysis of each new raws batch we buy and this is enough. Since 2014 this supplier offers and provides us raws of enough high quality and we know to value stable partnership relations and provided high product quality.
I hope herewith I thoroughly replied the question about our HGH.
I can not attach the file. cause it exceeds the allowed size. Here is the link:
Code: 
https://www.sendspace.com/file/7tdzqi
And one more thing: i translated this file today into English, so I hope it will be enough clear for you, whatever some mistakes in the terminology, etc. are possible.
Click to expand...
 
Dirty Gym Rat! said:
Hey bro I saw that you said you would test a vial of hyge if sent to you. I have a newer Chinese generic I just started about 3 weeks ago. Would you be willing to test it if I send you a vial? Thanks
Click to expand...
I will be testing hyges soon from another member.

What color top is your generic and who is from?

mands
 
Victor said:
T


It's not grey tops Then.
Click to expand...
He sold them as grey tops. I'm trying to get a pic of the box they came in. As I know what the grey tops from HK and TP look like.

mands
 
mands said:
I will be testing hyges soon from another member.

What color top is your gegeric and who is from?

mands
Click to expand...
The generic is a blue top. It's called puretropin and its manufactured by ironlion-labs. I am currently 3 vials into my second kit and starting too get good fat loss and feeling great. If possible I would really like to see how this would test. Thanks a lot bro.
 
Dirty Gym Rat! said:
The generic is a blue top. It's called puretropin and its manufactured by ironlion-labs. I am currently 3 vials into my second kit and starting too get good fat loss and feeling great. If possible I would really like to see how this would test. Thanks a lot bro.
Click to expand...
I'll see what I can do.

mands
 
mands said:
You are correct! I'll get the right generic name when I receive the HPLC on it.

mands
Click to expand...

we should get TP greytop and get it tested, there are few americans here that use it. let's get someone to send you a vial damn it :)
 
Sampei said:
we should get TP greytop and get it tested, there are few americans here that use it. let's get someone to send you a vial damn it :)
Click to expand...
Exactly!!! The Grey Tops I've been very interested in testing since they are giving such great numbers on serum and igf-1 levels.

mands
 
mands said:
Exactly!!! The Grey Tops I've been very interested in testing since they are giving such great numbers on serum and igf-1 levels.

mands
Click to expand...

there are few members using it, let's find them, I'll post a thread asking for one vial to be sended to you. happy with that?
 
Sampei said:
there are few members using it, let's find them, I'll post a thread asking for one vial to be sended to you. happy with that?
Click to expand...
That works and hotdog posted some members using it so we shall see if they want to contribute 1 vial.

Gonna be backed up for a week or so getting others caught up. So, a couple weeks should be good.

mands
 
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