Muscle Strength, Physical Activity May Protect Men Against Bone Fragility

Michael Scally MD

Doctor of Medicine
10+ Year Member
Researchers reported, "men who are physically active and retain muscle strength in old age may be helping to protect themselves against bone fragility." Researchers found that "men in the highest quartile for physical activity had a significant 7% greater bone strength index (BSI) and 4% greater polar strength strain index (SSIp) than those in the lowest quartile for activity, after taking into consideration confounding factors including age, race, weight, and limb length." Furthermore, "men with the greatest leg power had both higher total bone cross sectional area (3%) and SSIp (5%) than those with the least leg power." The findings of this study suggest the importance of maintaining levels of physical activity and muscle strength in older men to prevent bone fragility.


Cousins JM, Petit MA, Paudel ML, et al. Muscle power and physical activity are associated with bone strength in older men: The osteoporotic fractures in men study. Bone;In Press, Uncorrected Proof.

The purpose of these analyses was to explore whether physical activity score, leg power or grip strength were associated with tibia and radius estimates of bone strength, cortical density, or total bone area.

Peripheral quantitative computed tomography (pQCT) was used to compare tibial and radial bone volumetric density (vBMD, mg/cm3), total (ToA, mm2) and cortical (CoA, mm2) bone area, and estimates of bone compressive strength (bone strength index, BSI) and bending strength (polar strength strain index, SSIp) in a subset (n = 1171) of men (>= 65 years) who participated in the multi-site Osteoporotic Fractures in Men (MrOS) study.

Physical activity was assessed by questionnaire (PASE), leg power by Nottingham Power Rig, and grip strength by a hand-held Dynamometer. Participants were categorized into quartiles of PASE, grip strength or leg power. The model was adjusted for age, race, clinic, weight, and limb length.

In the tibia, BSI (+ 7%) and SSIp (+ 4%) were highest in the most active physically quartile compared to the least active (p < 0.05). At the 4% site of the tibia, men with the greatest leg power had both greater ToA (+ 5%, p < 0.001) and BSI (+ 5.3%, p = 0.086) compared to men with the least leg power. At the 66% site of the tibia, the men with the highest leg power, compared to the men with the lowest leg power, had greater ToA (+ 3%, p = 0.045) SSIp (+ 5%, p = 0.008). Similar results were found at both the distal and midshaft of the radius.
 
great read...thanks


Thanks. There are many times I do not want to post the obvious, but research many times is so far behind what is plainly clear. The Meso readers undoubtedly know that muscle strength and exercise will positively impact bone health (as well as others).
 
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