Never done actual HGH, but I did Ipamorelin/MOD GRF (peptides; the form being a growth hormone releasing peptide and the latter being a growth hormone releasing hormone) for a long time, like over a year. My IGF-1 levels on the peptides was 329. It definitely improved my sleep, but unfortunately it really made my pre-existing gyno worse. Now when I take it, I still get puffy nipples. I just don't seem to respond well to increased IGF-1. I can let my E2 ride super high and not have any issues, but take Ipamorelin/MOD GRF for a few days and my nips are puffed up. I had full gland removal; I am sure some of it is fluid retention,
Originally when my gyno started getting so much worse I thought it must be due to SARMs I was taking at the time, but years later doing more research I found that GH does induce gyno (I linked to studies in another thread and I don't feel like digging for them right now), so looking back it makes sense--the steady titty growth over that year and a half or so ... probably was mostly induced by the high IGF-1
So now I stay away from the stuff. It is normal AAS only for me from now on. No GH/GHRPs, no myostatin inhibitors, no SARMs or insulin (I never touched insulin and never would have anyway).
The only thing I am considering is old school GHRP2 or GHRP6 for my next bulk, solely for the boost in hunger so I can eat more. If my nips puff up though it is getting axed.
That is just my experience. It seems like most guys don't have issues with IGF-1 and gyno, so I am an unlucky one in that regard