One more thing

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you dpn't know much about me. I'm smoked very strong high marijuana known as skunk in the UK from the ages of 17 to 29. Heavily. I used to mix it with tobacco because thats how it's used over here. i started smoking in college and then it worse. I aslo had a drink problem. I quit smokin dop at 29, I was prescribed SSRI''sa t maximum dosage fpr years ince coming aff anabolics. I was prescribed prozac at 20 gmg after I cam off my thirt cycle. i felt better and jumped on to Test e at 500 mg for another 12 weeks. I was still on gthe prozac. t hen came off and was put on cipralex, cipramil, flupxetine again, sertraline and mirtazipe.

My T levels were through the roof. I never gaine any muslce from my steroid use. None what so ever.
 
sade said: you dpn't know much about me.

I think we know enough sade. You started this thread last Christmas, And this is post #307. Is there something more you would like us to know...and how will more information help? What is it you are expecting now from the members of this board. If you just want to cry about your crappy situation for the next 5 months, and not take heed of the advice given here, or if you just want to play music videos, you might do well to move on over to facebook. See if someone over there can tell you..."sade, your problem is, you dont drink enough booze!"
 
you dpn't know much about me. I'm smoked very strong high marijuana known as skunk in the UK from the ages of 17 to 29. Heavily. I used to mix it with tobacco because thats how it's used over here. i started smoking in college and then it worse. I aslo had a drink problem. I quit smokin dop at 29, I was prescribed SSRI''sa t maximum dosage fpr years ince coming aff anabolics. I was prescribed prozac at 20 gmg after I cam off my thirt cycle. i felt better and jumped on to Test e at 500 mg for another 12 weeks. I was still on gthe prozac. t hen came off and was put on cipralex, cipramil, flupxetine again, sertraline and mirtazipe.

My T levels were through the roof. I never gaine any muslce from my steroid use. None what so ever.

One thing's for certain, you tossed a few back before writing this post. I guess that spell checker in your brain wasn't working.
 
One thing's for certain, you tossed a few back before writing this post. I guess that spell checker in your brain wasn't working.

and "im smoked very strong high marijuana known as skunk..." hes drunk and smoked and its not the pot thats high.
maybe a few prayers would work. sade is out of control.
 
you dpn't know much about me. I'm smoked very strong high marijuana known as skunk in the UK from the ages of 17 to 29. Heavily. I used to mix it with tobacco because thats how it's used over here. i started smoking in college and then it worse. I aslo had a drink problem. I quit smokin dop at 29, I was prescribed SSRI''sa t maximum dosage fpr years ince coming aff anabolics. I was prescribed prozac at 20 gmg after I cam off my thirt cycle. i felt better and jumped on to Test e at 500 mg for another 12 weeks. I was still on gthe prozac. t hen came off and was put on cipralex, cipramil, flupxetine again, sertraline and mirtazipe.

My T levels were through the roof. I never gaine any muslce from my steroid use. None what so ever.

Maybe you should also investigate PSSD or pst -ssri sexual dysfunction, as one of the hallmarks is that it is very hard to treat via TRT or hormone supplementation. It's a bit like post finasteride synrome in that respect, although rarer and usually not as severe.
 
I think we know enough sade. You started this thread last Christmas, And this is post #307. Is there something more you would like us to know...and how will more information help? What is it you are expecting now from the members of this board. If you just want to cry about your crappy situation for the next 5 months, and not take heed of the advice given here, or if you just want to play music videos, you might do well to move on over to facebook. See if someone over there can tell you..."sade, your problem is, you dont drink enough booze!"

Well, it's not like that. I used to post a shit load of nonsensical threads and they all got merged in one.

Anyways my issue is deeper than 98% of guys on this planet. Yes, this whole planet.

I've always been a bit reckless but how far can one go? I started taking anabolic steroids with a mate at age 20-21. Did a lot of cycles. Used most of the stuff out there but the cycles were always 10 or sometimes 12 weeks max. I had never done a cycle longer than that.

One day I managed to get hold of some Test Enanthate from a chinese source and my mate got the same. He did a 10 weeker got lean, did pct and stayed off........Me? I did 12 weeks of 500 mg, pct then jumped straight back onto another 12 week cycle with no time off after pct. Just jumped straight back on like a nutter.

i had done 6 months of Test E and got depressed when I came off the six monther. I was still in pct and was prescribed fluoxetine 20 mg. I felt better in days. Finished pct and jumped straight back on to another 12 week cycle off 500 mg Testosterone Enanthate after already doing 6 non stop. I then came off a month before my 25th birthday after using only nolvadex pct and had symptoms of Hypogonadism ever since but my Total Testosterone levels were always right at or sometime over the range. Free T and Bioavailable always over the range. DHT over the range in the two tests I've had enough. Free Androgen Index is over range.

It's not my testosterone levels. It's my LH levels. They're through the roof, sky high and yet so is my T. High LH means that the pituitary gland in the brain thinks my T is low and that the testicles aren't producing enough. In other words it's screaming for more T. I need more T and thats it. Booze is a problem I have to beat but so is this rare condition I was born with:[ame=http://en.wikipedia.org/wiki/Mild_androgen_insensitivity_syndrome]Mild androgen insensitivity syndrome - Wikipedia, the free encyclopedia[/ame]

An example of a hypogonadism resulting from the lack of hormone response is androgen insensitivity syndrome, where there are inadequate receptors to bind the testosterone, resulting in a female appearance despite XY chromosomes.
Source: [ame=http://en.wikipedia.org/wiki/Hypogonadism]Hypogonadism - Wikipedia, the free encyclopedia[/ame]
 
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Vatsalya V, Issa JE, Hommer DW, Ramchandani VA. Pharmacodynamic effects of intravenous alcohol on hepatic and gonadal hormones: influence of age and sex. Alcohol Clin Exp Res 2012;36(2):207-13. Pharmacodynamic Effects of Intravenous Alcohol on Hepatic and Gonadal Hormones: Influence of Age and Sex

BACKGROUND: Growth hormone (GH)-insulin-like growth factor-1 (IGF-1) axis and gonadal hormones demonstrate extensively associated regulation; however, little is known about the effects of acute alcohol exposure on these hormones. This study examined the effects of intravenous alcohol on the GH-IGF-1 axis and gonadal hormone concentrations, and the influence of age and sex on their regulation.

METHODS: Forty-eight healthy volunteers (24 men and 24 women each in the 21 to 25 and 55 to 65 year age groups) underwent a 2-session single-blinded study. Subjects received in randomized counter-balanced order, alcohol infusions, individually computed based on a physiologically based pharmacokinetic model, to maintain a steady-state ("clamped") exposure of 50 mg% or saline for 3 hours in separate sessions. Blood samples collected at baseline and postinfusion in each session were assayed for levels of GH, IGF-1, free testosterone, and estradiol.

RESULTS: Acute alcohol administration resulted in changes in gonadal hormones that differed by sex. Change in free testosterone showed a significant treatment x baseline interaction (p < 0.001), indicating that alcohol-induced suppression of testosterone occurred predominantly in men. On the other hand, change in estradiol showed a significant treatment x sex interaction (p = 0.028), indicating that alcohol-induced increases in estradiol occurred predominantly in women. There was a trend for alcohol-induced decreases in IGF-1 levels. Change in GH showed a significant main effect of baseline (p < 0.001) and a trend for treatment by baseline interaction, suggesting an alcohol-induced decrease in individuals with high baseline GH values. There was also a significant main effect of sex (p = 0.046) indicating that men had greater changes in GH across treatment compared with women.

CONCLUSIONS: Alcohol induced a complex pattern of hormonal responses that varied between younger and older men and women. Some of the observed sex-based differences may help improve our understanding of the greater susceptibility to alcohol-related hepatic damage seen in women.
 
Vatsalya V, Issa JE, Hommer DW, Ramchandani VA. Pharmacodynamic effects of intravenous alcohol on hepatic and gonadal hormones: influence of age and sex. Alcohol Clin Exp Res 2012;36(2):207-13. Pharmacodynamic Effects of Intravenous Alcohol on Hepatic and Gonadal Hormones: Influence of Age and Sex

BACKGROUND: Growth hormone (GH)-insulin-like growth factor-1 (IGF-1) axis and gonadal hormones demonstrate extensively associated regulation; however, little is known about the effects of acute alcohol exposure on these hormones. This study examined the effects of intravenous alcohol on the GH-IGF-1 axis and gonadal hormone concentrations, and the influence of age and sex on their regulation.

METHODS: Forty-eight healthy volunteers (24 men and 24 women each in the 21 to 25 and 55 to 65 year age groups) underwent a 2-session single-blinded study. Subjects received in randomized counter-balanced order, alcohol infusions, individually computed based on a physiologically based pharmacokinetic model, to maintain a steady-state ("clamped") exposure of 50 mg% or saline for 3 hours in separate sessions. Blood samples collected at baseline and postinfusion in each session were assayed for levels of GH, IGF-1, free testosterone, and estradiol.

RESULTS: Acute alcohol administration resulted in changes in gonadal hormones that differed by sex. Change in free testosterone showed a significant treatment x baseline interaction (p < 0.001), indicating that alcohol-induced suppression of testosterone occurred predominantly in men. On the other hand, change in estradiol showed a significant treatment x sex interaction (p = 0.028), indicating that alcohol-induced increases in estradiol occurred predominantly in women. There was a trend for alcohol-induced decreases in IGF-1 levels. Change in GH showed a significant main effect of baseline (p < 0.001) and a trend for treatment by baseline interaction, suggesting an alcohol-induced decrease in individuals with high baseline GH values. There was also a significant main effect of sex (p = 0.046) indicating that men had greater changes in GH across treatment compared with women.

CONCLUSIONS: Alcohol induced a complex pattern of hormonal responses that varied between younger and older men and women. Some of the observed sex-based differences may help improve our understanding of the greater susceptibility to alcohol-related hepatic damage seen in women.

Help me out here Doc. Did the study conclude, alcohol makes men less manly and woman more womanly? In a nutshell? And what was their indicator for the female hepatic damage?
 
Right exactly three months from now I got to get my shit together. It may take longer than that but now that I think I know that I'm in no rush to get this shit fixed asap has put my mind at ease a bit. Thank fuck.

I've been off booze with clonazepam but still have other issues to tackle. My next blood test will show elevated T and LH levels. No doubt about it. Elevated motherfucking T and LH levels.
 
Serious questions now guys.

I've been off the booze using clonazepam to get me off of it.

I'm living healthy and trying to get good sleep and trying my very hardest to give up bad habits.

I'm in temp accomodation for 2-3 weeks and have exactly $1801.68 to get myself sorted out. I've cancelled the appointment with the endo but even he if he won't help which I know he won't, is this enough money to get myself sorted out for a year at least?

I have no job and am on sickness and mental illness benefit. I'm trying to find work but should I put this testosterone TRT shit off until I'm secure and sorted financially and physically, mentally?

It's just that there is this girl who is waiting for me to sort my shit out. In other words I abused high doses of Test Enanthate and now my dick doen't work because I have fuck all libido. Nothing turns me on. On Test E my dick was rock hard every 5-10 minute. Nothing could keep it down. Even looking at fat girls bodies made my dick rise and stay hard for half a fucking hour or over.

I took this shit for a year at cycle dosages.

Should I concentrate on the addiction substance issues first or the T issue? My next app with the endo is in August.

I know I'm all messed up and all that but I should I just carry on and take as long as it takes to get my issues sorted or pump some Test E in me300 MG a week and see if that makes my dick work.
 
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I maintain that you should get the genetic test for MAIS. Given how wildly your hormones changed when you cleaned up, there's a chance you might not have it. If you don't have it, there's a good chance your body could completely return to normal after an extended sobriety.

The important point here is that taking more T could actually make you worse. At this point, I think it is critical that you get to the root cause of your problem: is it genetic, or did chronic alcohol abuse have a very bizarre impact on your endocrine system? At this point, we can only guess, and that's not good.

The treatment would be drastically different, depending on the answer to this question. That's why you should just get the test, and move on with your life.
 
I maintain that you should get the genetic test for MAIS. Given how wildly your hormones changed when you cleaned up, there's a chance you might not have it. If you don't have it, there's a good chance your body could completely return to normal after an extended sobriety.

The important point here is that taking more T could actually make you worse. At this point, I think it is critical that you get to the root cause of your problem: is it genetic, or did chronic alcohol abuse have a very bizarre impact on your endocrine system? At this point, we can only guess, and that's not good.

The treatment would be drastically different, depending on the answer to this question. That's why you should just get the test, and move on with your life.

...stop feeding the troll -- seriously, just let this thread die off already...hebs
 
I maintain that you should get the genetic test for MAIS. Given how wildly your hormones changed when you cleaned up, there's a chance you might not have it. If you don't have it, there's a good chance your body could completely return to normal after an extended sobriety.

The important point here is that taking more T could actually make you worse. At this point, I think it is critical that you get to the root cause of your problem: is it genetic, or did chronic alcohol abuse have a very bizarre impact on your endocrine system? At this point, we can only guess, and that's not good.

The treatment would be drastically different, depending on the answer to this question. That's why you should just get the test, and move on with your life.

Before the test though I'm going to pull 3 more pulsating LH's and top end Total or over BAT or Free T (even with high SHBG) total T's first.

It's not booze whats caused it because when I had the test last Sept, I was at my worst with the boozing. It was December last year I found out the news from the endo which shook me up and I knew from there that some thing went wrong but I was drinking most of the time so it wasn't being sober or anything to do with me or me drinking plus my LH has come back up again at 8.8. June 2010 it was 9.3.

I'm getting tested again between 8-9 Tuesday morning. I think I know whats gone wrong and it wasn;t getting sober because I was only really sober for 21 days max,. I was still drinking on weekends.

I think I know what did this and it wasn't booze but I'm working on that now. I'll get the genetic test but blood work is more important for me at the minute.

I want Total T levels at top end of range or above and LH above 10 three more time from now. One LH X T next week, one the month after and the last one the month after that. No booze. No drugs. Healthy, fit, well.

I don't need need anything else right now; Not at this time. I can get the test someday but not now. I don't have time right now.

ps:

I will need an high ASI to get that test. Those blood records are from 2010-2011.

A high ASI in a normal phenotypic male, can be indicative of MAIS, and may warrant genetic testing.
 
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