Alright so he thinks it's fine to change up the injection interval from the recommended schedules in the studies. He thinks adherance played a big role in efficient therapy and many casuals will forget to inject more frequently. He finds that in the Initial phase, you should stick to the guidelines and later change up the injection frequency, like from 1mg every 7 days, to 1 mg every 5 days, increasing the peak concentrations from 1.4mg to 1.8mg.
Microdosing is interesting for people who hit their goal weight and achived satisfying glycemic control.
This is my summary and I don't claim accuracy.
The argument I've read before, that you should stick to the study protocol (bc they must know whats right) doesn't make so much sense to me for the reason mentioned (you need adherance to replicate your hypothesis), but I also like to microdose my TRT even taking it SC for more estrogen control. And there are no studys on, when I last checked and even the leaflets in my prescription tell me to inject 250mg every 2 weeks for TRT. Crazy peaks make no sense, when there is a huge drop afterwards. Balance & a stable level is key with Testosterone and maybe even GLP-1 agonists, who knows. Only time will tell.