That thought has definitely crossed my mind, but no, as far as feeling and functioning I'm great.
I do stay heavily on top of using different probiotic strains and feed them plenty of fiber every day, and I never take a large amount of supplements in an empty stomach.
I start every day with a smoothie that has at least 40g protein and 18-25g of fiber and absolutely loaded with different probiotic strains as a solid baseline, and only a couple things go into my stomach before that, and aside from that I eat a ridiculously clean whole food pescatarian diet. Pretty much only raw fruits, veggies, ancient grains, nuts, beans, lentils, Shrimp, Mackerel, sardines, local organic eggs and local dairy. I'll do chicken sometimes, but chicken, beef, pork, and other denser proteins have always sat funny for me. I try to really stay on top of gut health since that's where everything else health wise begins.