egruberman
Well-known Member
I took a mere 2.5mg before bed last night and this morning I feel light tremors through my arms(similar to clen) and occasional tingling in my hands.
That's a really low dose at which to see what is a relatively uncommon side effect. If you wanted to try again, maybe take CoQ10 for a couple days first and see if it repeats. Pravastatin may be an alternative.
Do you know if it goes away over a few days or is this basically already telling me rosuvastatin is not gonna work for me? I also have ezetimibe and bempedoic acid so I can trial that next to see how I do
It may subside. If I were in your position, I'd try it for a little, coupled with CoQ10 as I mentioned, but it may be that you're sensitive to the drug. If it turns out that you're intolerant, ezetimibe plus bempedoic acid is a good alternative. If you need more aggressive lipid management, start contemplating a PCSK9 inhibitor like Repatha or Inclirisan.
@egruberman You're very knowledgeable. What are your thoughts on managing triglycerides, both through diet/supps and meds?
Putting aside genetic variation, high triglycerides are typically the result of metabolic dysregulation. Trigs are a risk factor for ASCVD in that they increase inflammation, directly damage the endothelium, and increase atherogenic particles.
Interventions include diet and exercise. Most folks with high trigs don't do enough cardio and are eating too many refined carbs. Supplements that influence trigs are berberine, psyllium husks and Omega 3 fatty acids. Drugs that lower trigs are statins and fibrates.
For trigs especially, start with lifestyle. If a statin is needed, enjoy the concomitant reduction in trigs. I wouldn't recommend fibrates unless someone had a particular genetic predisposition to high trigs.