Greetings scrubs. I have an addendum to make regarding my post about garlic and blood pressure.
Specifically those of you who are looking for ways to manage hypertension and cardiovascular support, specifically when purchasing a garlic supplement, one should look for garlic supplements that advertise a %Allicin yield(Allicin is the active ingredient). While most garlic extracts will contain some amount of Allicin, it’s better to find one specifically trying to provide the highest concentration possible of this component.
Effects of Allicin on Hypertension and Cardiac Function in Chronic Kidney Disease
Effect of Allicin From Garlic Powder on Serum Lipids and Blood Pressure in Rats Fed With a High Cholesterol Diet - PubMed
In the present study, we evaluated the therapeutic effect of allicin on hypertension and cardiac function in a rat model of CKD. We provide evidence that allicin improved renal function, partially decreased systemic hypertension, improved the function of the heart, and prevented its remodeling, in addition to almost abolishing the oxidative stress. The protective effects of allicin were mediated by reducing the AT1R and Keap1 expression. In contrast, allicin increased the Nrf2 expression and consequently their target genes (CAT, SOD, and GPx), which led to decrease in hypertension, oxidative stress, ultimately improving cardiac structure and performance.
The beneficial effects of garlic against cardiovascular disorders such as stroke, coronary artery disease and hypertension are well known [
8–
11]. It has been suggested that the active substance in garlic may be one of the sulphur compounds; among them, allicin is considered as one of the highest bioactive organosulphur compounds from garlic [
12]. Despite the fact that the effect of whole garlic extract on hypertension is well known, the effects of allicin on blood pressure and renal and cardiac function specifically in CKD are scarce [
17–
19]. Thus, this study was designed to assay the usefulness of allicin in treatment of complications associated with CKD.
Stay safe boys