Tobacco

Smoking something without the intention of getting high seems to be along the same lines of rubbing one out without a happy ending. Never really saw the appeal personally.
 
No it really tasted like shite.

I've finally cracked it!

Been exactly where you're at now. Exactly. Excited to be done. 3-5 months under my belt. Don't want them anymore.

Still started back up.

Don't flirt with them again bro. I got 2 years right now, and I'm terrified of them. Don't want one, but it only takes one drunk night, and about 5-10 cigs, and they don't taste like shit anymore.
 
FWIW...I miss weed and if I didn't have so much riding on staying on the right side of the law I'd happily smoke again.
 
Laws change, and so do people. Really I have seen that as long as you are talking personal possession, the matter is about state'$ Income... As far are politically and drug testing in business, thats another story. But I do think the days of the threat of a hair sample over some POT are fading...:)

IMO and based on past experience in collage many years ago, there is no substance on the planet capable of imparting such a GRAND SMILE....

I fear will eventually prove that the only reason it was ever outlawed was - Politic$ - because it just might grow freely in fields of gold, thus minimizing profit..

FWIW...I miss weed and if I didn't have so much riding on staying on the right side of the law I'd happily smoke again.
 
Been exactly where you're at now. Exactly. Excited to be done. 3-5 months under my belt. Don't want them anymore.

Still started back up.

Don't flirt with them again bro. I got 2 years right now, and I'm terrified of them. Don't want one, but it only takes one drunk night, and about 5-10 cigs, and they don't taste like shit anymore.

No mate, I'm not gonna! I can feel that one cigarette today on my chest. Funny, the healthier I am the more fucked I feel when I do anything unhealthy. Feel bloody terrible for having a drink last night. Only had 4 pints as well.
 
Chen LS, Bloom AJ, Baker TB, et al. Pharmacotherapy Effects on Smoking Cessation Vary with Nicotine Metabolism Gene (CYP2A6). Addiction. Pharmacotherapy Effects on Smoking Cessation Vary with Nicotine Metabolism Gene (CYP2A6) - Chen - Addiction - Wiley Online Library

BACKGROUND AND AIMS: Evidence suggests that both the nicotinic receptor alpha5 subunit (CHRNA5) and Cytochrome P450 2A6 (CYP2A6) genotypes influence smoking cessation success and response to pharmacotherapy. We examine the effect of CYP2A6 genotype on smoking cessation success and response to cessation pharmacotherapy, and combine these effects with those of CHRNA5 genotypes.

DESIGN: Placebo-controlled randomized smoking cessation trial.

SETTING: Ambulatory care facility in Wisconsin, USA.

PARTICIPANTS: Smokers (N=709) of European ancestry were randomized to placebo, bupropion, nicotine replacement therapy, or combined bupropion and nicotine replacement therapy.

MEASUREMENTS: Survival analysis was used to model time to relapse using nicotine metabolism derived from CYP2A6 genotype-based estimates. Slow metabolism is defined as the lowest quartile of estimated metabolic function.

FINDINGS: CYP2A6-defined nicotine metabolic function moderated the effect of smoking cessation pharmacotherapy on smoking relapse over 90 days (Hazard Ratio (HR) = 2.81, 95%CI=1.32-5.99, p=0.0075), with pharmacotherapy significantly slowing relapse in fast (HR=0.39, 95%CI=0.28-0.55, p=1.97x10-8), but not slow, metabolizers (HR=1.09, 95%CI=0.55-2.17, p=0.80). Further, only the effect of nicotine replacement, and not bupropion, varies with CYP2A6-defined metabolic function. The effect of nicotine replacement on continuous abstinence is moderated by the combined genetic risks from CYP2A6 and CHRNA5 (interaction effect size=0.74, 95%CI=0.59-0.94, p=0.013).

CONCLUSIONS: Nicotine replacement therapy is effective amongst individuals with fast, but not slow, CYP2A6-defined nicotine metabolism. The effect of bupropion on relapse likelihood is unlikely affected by nicotine metabolism as estimated from CYP2A6 genotype. The variation in treatment responses amongst smokers with genes may guide future personalized smoking cessation interventions.
 
Does it taste like shite? Or does it taste delicious? You know you want that delicious nicotine flooding your system and hitting your dopamine receptors ;) lol

I'm messing with ya. Good on you for quitting. My plan is to smoke for a yr and then quit. I only have a few cigarettes a day and some days (like today probably) i will have none. My achilles heel or weakness seems to be when I see a hot girl smoking. I just get this intense urge to have one. This doesnt happen when I see dudes smoking. lol

I havent seen any cute girls smoking today so i probably wont have one! :)

As a non-smoker all I can say is a hot chick smoking makes me want to puke...I wouldn't even let her polish my knob smelling like smoke.
 
As a non-smoker all I can say is a hot chick smoking makes me want to puke...I wouldn't even let her polish my knob smelling like smoke.

Oh c'mon... you'd make an exception for her, wouldn't you? :drooling:

smoker1.jpg


Or her?

b,w,smoking,woman,blonde,eyes,sexy-6e26ddf6b1b27a9d280fe11209522e5e_h.jpg
 
I think I know the chick in the top pic. LOL

Now... If you can just find me a PIC of a smok'n hotty with a nice fat copenhagen in her mouth. Now there's a fantasy. So I am envisioning her giving a nice head job and the coming off it only to spit tobacco all over it and the slide it down on it...:eek::drooling:

But I do think I found my new favorite tobacco related site...

CHICKS N DIP
 
Last edited:
I wish I could kick the habit too... I have been chewing cope since I was 12 . Sometimes I change it up and go to skoal fine cut but there is nothing like copenhagen. The first thing I do when I roll out of bed it throw in a lip then hit the shower.

Horrible habit to have and I hate that I still do it. I think it is tougher to stop chew than it is cigs.

By the way nice website you posted - never seen it before - I now have a new favorite.
 
CVS Plans to End Sales of Tobacco Products
http://www.nytimes.com/2014/02/06/b...s-of-tobacco-products-by-october.html?hp&_r=0

CVS/Caremark, the country’s largest drugstore chain, announced on Wednesday that it planned to stop selling cigarettes and other tobacco products by October.

The company’s move was yet another sign of its metamorphosis into becoming more of a health care provider than a largely retail business, with its stores offering more miniclinics and health advice to aid customers visiting its pharmacies.

While the company’s decision will cost it an estimated $2 billion in sales from tobacco buyers, that is a mere dent in its overall sales of $123 billion in 2012.

“We have about 26,000 pharmacists and nurse practitioners helping patients manage chronic problems like high cholesterol, high blood pressure and heart disease, all of which are linked to smoking,” said Larry J. Merlo, chief executive of CVS. “We came to the decision that cigarettes and providing health care just don’t go together in the same setting.”
 
CVS Plans to End Sales of Tobacco Products
http://www.nytimes.com/2014/02/06/b...s-of-tobacco-products-by-october.html?hp&_r=0

CVS/Caremark, the country’s largest drugstore chain, announced on Wednesday that it planned to stop selling cigarettes and other tobacco products by October.

The company’s move was yet another sign of its metamorphosis into becoming more of a health care provider than a largely retail business, with its stores offering more miniclinics and health advice to aid customers visiting its pharmacies.

While the company’s decision will cost it an estimated $2 billion in sales from tobacco buyers, that is a mere dent in its overall sales of $123 billion in 2012.

“We have about 26,000 pharmacists and nurse practitioners helping patients manage chronic problems like high cholesterol, high blood pressure and heart disease, all of which are linked to smoking,” said Larry J. Merlo, chief executive of CVS. “We came to the decision that cigarettes and providing health care just don’t go together in the same setting.”

This is great news . Hopefully more of these retailers will follow suit.
 
Not trying to be pro tobacco but why do schizophrenics have a statistically significant reduced rate of developing lung cancer when the prevalence of smoking in that population is extremely high.
 
Cytisine versus Nicotine for Smoking Cessation
http://www.nejm.org/doi/full/10.1056/NEJMoa1407764#t=article

Placebo-controlled trials indicate that cytisine, a partial agonist that binds the nicotinic acetylcholine receptor and is used for smoking cessation, almost doubles the chances of quitting at 6 months.

Cytisine is a plant-based alkaloid found in members of the Leguminosae family. Like varenicline[Chantix], cytisine is a partial agonist of nicotinic acetylcholine receptors (nAChRs).

Cytisine is a generic agent currently manufactured by Sopharma as Tabex and by Aflofarm Pharma as Desmoxan. It has been available both with and without prescription for smoking cessation since the 1960s, largely in Eastern Europe.

Given that no trials have compared cytisine with nicotine-replacement therapy, we designed a noninferiority trial to investigate whether cytisine was at least as effective as nicotine-replacement therapy.

When combined with brief behavioral support, cytisine was found to be superior to nicotine-replacement therapy in helping smokers quit smoking, but it was associated with a higher f
 
Back
Top