What are acceptable serum concentration of Deca and EQ for PCT?

[Wrangel7]

I'm coming off a major blast of nandrolone decanoate and boldenone undecylenate and sustanon. Sustanon is simpler as you can simply plot out the serum concentration of the longest ester of exogenous testosterone and when it reaches below about 100 ng/dl of exogenous testosterone then PCT is appropriate to begin. However, what are the serum levels of nandrolone and boldenone which allow for an appropriate start to PCT.

For context the blast involved about:
1400mg/week Deca
520mg/week EQ

I am not planning on cruising but hoping to come off completely for personal reasons.

So I am planning on cessation of Deca and EQ followed by a phase of shorter esters whilst the longer esters clear and I would like this phase to not be excessively long and then to PCT. Does anyone have experience or knowledge on what serum concentrations of the above are acceptable for PCT?

I cannot seem to find any literature on the serum concentrations of these compounds which make PCT appropriate. Is it 50ng/dl? Lower?

Thank you.

 

[b6798045]

That is a good question, I always hear 5 half lives of almost any drug is considered "cleared out" from the body. Now for their metabolites, I am not sure, some say you need a lot more time for Nandrolone clearance time due to their prolactin affect of HPTA.

 

[Wrangel7]

I always hear 5 half lives of almost any drug is considered "cleared out" from the body.

10 half-lives of X deca/week is the equivalent of 5 half-lives of Y deca/week, so this advice isn't applicable unless we are talking about the serum concentration from 5 half-lives of a specific Z deca a week, which would give us a serum concentration estimate in ng/dl which then kind of defeats the whole half-life conversation in the first place and brings us back to the relevant question of what serum concentration is appropriate.

E.g. serum conc from (roughly):
2400mg/week after cessation after 8 half-lives ≈ 9ng/dl
300mg/week after cessation after 5 half-lives ≈ 9ng/dl

That is a good question. [...] Now for their metabolites, I am not sure, some say you need a lot more time for Nandrolone clearance time due to their prolactin affect of HPTA.

 

[Wrangel7]

10 half-lives of X deca/week is the equivalent of 5 half-lives of Y deca/week, so this advice isn't applicable unless we are talking about the serum concentration from 5 half-lives of a specific Z deca a week, which would give us a serum concentration estimate in ng/dl which then kind of defeats the whole half-life conversation in the first place and brings us back to the relevant question of what serum concentration is appropriate.

E.g. serum conc from (roughly):
2400mg/week after cessation after 8 half-lives ≈ 9ng/dl
300mg/week after cessation after 5 half-lives ≈ 9ng/dl

Forgive the math if it isn't accurate and/or precise.

 

[iris]

@narta

 

[narta]

10 half-lives of X deca/week is the equivalent of 5 half-lives of Y deca/week, so this advice isn't applicable unless we are talking about the serum concentration from 5 half-lives of a specific Z deca a week, which would give us a serum concentration estimate in ng/dl which then kind of defeats the whole half-life conversation in the first place and brings us back to the relevant question of what serum concentration is appropriate.

E.g. serum conc from (roughly):
2400mg/week after cessation after 8 half-lives ≈ 9ng/dl
300mg/week after cessation after 5 half-lives ≈ 9ng/dl

That is correct. But 5 hl is a (correct) rough estimate that one is below the threshold for the HTPA to start the feedback loop. Because you have individual levels of esterase, lipase enzymes plus carrier oil of choice that all effect the terminal half life.

Nandrolone specifically, has metabolites that negatively impact the axis so even a minuscule/trace amount can have negative feedback.

So start at 5hl and go from there with the appropriate hormone tests.

P.S. If you choose to substitute Deca with NPP beware of the compounding effect. Levels will come down, but more slowly, its still nandrolone so levels will linger for longer.

 

[iris]

Thank you