There isn't anything special about the receptors for the first cycle: there doesn't have to be a fear of ruining a golden opportunity. The opportunity will always be there.
The principal reasons that the increase in mass, compared to right before the cycle, is typically so much better for a first cycle is simply that the starting point is lower in mass.
But, back to your cycle:
For a 2 week cycle to be very effective, the dosage level needs I think to be at least 1000 mg/week, although in the special case of using trenbolone acetate and Dianabol it can be as low as 700 mg total (50 mg/day of each.)
I would revise the cycle to:
Day 1: TP 450 mg
Days 2-10 150 mg/day
OR:
Day 1: TP 600 mg
Days 3, 5, 7, and 9: 300 mg
As for HCG, for 2 week cycles I've never developed a system (meaning, used it myself many times and saw what it did for others many times). It really is not necessary for 2 on / 4 off. I would save it for a later occasion. Where it would have more use is with extended cycles of 2 on / 2 off or especially 2 on / 1 off.
I would have enough Clomid or Nolvadex on hand to be able to use it during the cycle in case nipple sensitivity appeared.
If combining Clomid and Nolvadex for PCT, my preferred method is:
Nolvadex: Day 1 60 mg in divided doses (for example 20 mg three times). After this, either 10 mg/day or 20 mg every other day.
Clomid: Day 1: 150 mg in divided doses. After this, either 25 mg/day or 50 mg every other day.
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