MESO-Rx
Anabolic Steroids
Can touching a barbell in the gym get you sick with the coronavirus?
- Thread starter Michael Scally MD
- Start date
But... guys here say it’s not lethal. And masks are useless. None of these guys finished school, but still...
COVID-19 and Hypogonadism
Men show higher vulnerability to severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection (COVID-19) and present with depleted testosterone levels. Reports pertaining to high luteinizing hormone (LH), while diminished levels of in COVID-19 patients negate the hypothalamic-pituitary-testicular (HPT) axis mediated lowering of testosterone.
Although not evidenced, high testicular expression of angiotensin-converting enzymes-2 (ACE2), that aids viral entry into cells, may suggest direct viral-testicular invasion. However, secondary inflammation and oxidative stress (OS), owing to SARS-CoV-2 infection, are more likely to impair steroidogenesis.
Moreover, blockage of ACE2 aided angiotensin II into angiotensin (1-7) conversion may also affect testosterone synthesis. SARS-CoV-2, by mimicking adrenocorticotrophic (ACTH) hormones, may trigger host antibodies against the ACTH molecules to suppress host stress response.
This commentary concisely presents the possible mechanisms by which SARS-CoV-2 infection may affect testosterone levels, which possibly result in compromised male reproductive health.
Sengupta P, Dutta S. COVID-19 and hypogonadism: secondary immune responses rule-over endocrine mechanisms. Hum Fertil (Camb). 2021 Jan 13:1-6. doi: 10.1080/14647273.2020.1867902. Epub ahead of print. PMID: 33439057. https://www.tandfonline.com/doi/abs/10.1080/14647273.2020.1867902
Men show higher vulnerability to severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection (COVID-19) and present with depleted testosterone levels. Reports pertaining to high luteinizing hormone (LH), while diminished levels of in COVID-19 patients negate the hypothalamic-pituitary-testicular (HPT) axis mediated lowering of testosterone.
Although not evidenced, high testicular expression of angiotensin-converting enzymes-2 (ACE2), that aids viral entry into cells, may suggest direct viral-testicular invasion. However, secondary inflammation and oxidative stress (OS), owing to SARS-CoV-2 infection, are more likely to impair steroidogenesis.
Moreover, blockage of ACE2 aided angiotensin II into angiotensin (1-7) conversion may also affect testosterone synthesis. SARS-CoV-2, by mimicking adrenocorticotrophic (ACTH) hormones, may trigger host antibodies against the ACTH molecules to suppress host stress response.
This commentary concisely presents the possible mechanisms by which SARS-CoV-2 infection may affect testosterone levels, which possibly result in compromised male reproductive health.
Sengupta P, Dutta S. COVID-19 and hypogonadism: secondary immune responses rule-over endocrine mechanisms. Hum Fertil (Camb). 2021 Jan 13:1-6. doi: 10.1080/14647273.2020.1867902. Epub ahead of print. PMID: 33439057. https://www.tandfonline.com/doi/abs/10.1080/14647273.2020.1867902
One in three Los Angeles County residents have been infected with the coronavirus, according to new estimates by county scientists, an astonishing sign of how rapidly the virus is spreading in the hard-hit region.
The estimate, based on scientific modeling, means officials believe more than 3 million of L.A. County’s 10 million residents have been infected with the coronavirus, including nearly 13,000 who have died.
That’s more than triple the cumulative number of coronavirus cases that have been confirmed by testing. Officials have long believed that testing only captures a certain percentage of those who are infected because many with the virus don’t show symptoms or suffer only mild symptoms.
The rising number of those infected has actually slowed the pace of coronavirus transmission, as the virus is increasingly coming into contact with people who have survived the infection and likely developed immunity.
“Unfortunately, we are still engaging in behaviors that facilitate spread of the virus, so it is still able to find plenty of susceptible people to infect,” said Dr. Roger Lewis, director of COVID-19 hospital demand modeling for the L.A. County Department of Health Services.
About 75% of L.A. County’s population will need to be immune to the virus through widespread vaccinations to dramatically slow its spread, Lewis estimated. Even if half of L.A. County’s population were immune, “and yet we decide to just pretend that we don’t have to take precautions, we will still have a very, very devastating pandemic.”
L.A. County averaged more than 15,000 new coronavirus cases a day over the past week — one of the highest such rates seen so far in the pandemic.
Theworm
Well-known Member
Ok, dr scaly keeps posting how dreadful this is, highest death rate etc. last month we heard Biden talk about lockdowns and same with Cuomo.
Fast forward to today, numbers look worse, vaccine rollout slow, but now both of them are saying the direct opposite! Cuomo says we need to open biz ASAP, Biden says we need to open most schools within the next few months. How are people not outraged at the hypocrisy???
Fast forward to today, numbers look worse, vaccine rollout slow, but now both of them are saying the direct opposite! Cuomo says we need to open biz ASAP, Biden says we need to open most schools within the next few months. How are people not outraged at the hypocrisy???
Federal health officials sounded the alarm Friday about a fast spreading, far more contagious variant of the coronavirus that is projected to become the dominant source of infection in the country by March, potentially fueling another wrenching surge of cases and deaths.
In a study released on Friday, the Centers for Disease Control and Prevention said that its forecasts indicated outbreaks caused by the new variant could lead to a burgeoning pandemic this winter. It called for a doubling down on preventive measures, including more intensive vaccination efforts across the country.
The variant is not known to be more deadly or to cause more severe disease. But the dire warning — hedged by limited data about just how prevalent the variant first identified in Britain has become — landed in a week where the nation’s nascent vaccination campaign was hampered by confusion and limited supplies as demand grew among growing numbers of eligible people
Only 76 cases of the variant have been identified so far in the U.S., but the actual number is believed to be higher and is expected to spiral upward in the next few weeks, officials said. They emphasized that current mitigation strategies were effective against the new strain, exhorting Americans to be vigilant in wearing face masks, maintaining six or more feet of distance from other people, washing hands frequently, reducing interactions with people outside their households, limiting contacts and avoiding crowds.
Vaccinated - Moderna ... Ist Dose; 2nd Dose soon ...
Feels very good to be on the way ...
Minute Maid Stadium - Went pretty quick. About an hour from start to finish.
Yesterday, while reading tweets up pops an alert for COVID vaccine availability. https://twitter.com/HoustonHealth/status/1350105976838512640?s=20
They filled up within 10 minutes. I feel like I won the lottery or something.
Feels very good to be on the way ...
Minute Maid Stadium - Went pretty quick. About an hour from start to finish.
Yesterday, while reading tweets up pops an alert for COVID vaccine availability. https://twitter.com/HoustonHealth/status/1350105976838512640?s=20
They filled up within 10 minutes. I feel like I won the lottery or something.
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The recorded death count from the Covid-19 pandemic as of Thursday is nearing 2 million. The true extent is far worse.
More than 2.8 million people have lost their lives due to the pandemic, according to a Wall Street Journal analysis of data from 59 countries and jurisdictions. This tally offers the most comprehensive view yet of the pandemic’s global impact. Deaths in these places last year surged more than 12% above average levels.
Less than two-thirds of that surge has been attributed directly to Covid-19. Public-health experts believe that many, if not most, of the additional deaths were directly linked to the disease, particularly early in the pandemic when testing was sparse. Some of those excess deaths came from indirect fallout, from health-care disruptions, people avoiding the hospital and other issues.
To better understand the pandemic’s global toll, the Journal compiled the most recent available data on deaths from all causes from countries with available records. These countries together account for roughly one-quarter of the world’s population but about three-quarters of all reported deaths from Covid-19 through late last year.
The tally found more than 821,000 additional deaths that aren’t accounted for in governments’ official Covid-19 death counts.
MisterSuperGod
Well-known Member
i would've asked them if i could sock a few dingers while i wait, but that's just me.
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