Hello Canadian Brawners,
PRODUCT OF THE MONTH (DNP)
paretomeso@protonmail.com
DNP was a new product that was added to our line-up in late 2018. We will be running a promo on it for the duration of June and possibly beyond, if there's enough interest. Please reach out to me for more details
DNP (200mg x 30 Capsules) by PARETO
Originally used as an ignition source for dynamite, as well as a pesticide, researchers at Stanford University discovered that DNP causes weight loss in 1933. The late pioneer bodybuilding Dan Duchaine wrote about DNP for fat reducing weight loss and DNP has been used in the hard core bodybuilding underground for fat and weight loss for decades.
Compared to other thermo-genic, fat reducing, and weight loss agents such as the ephedrine/caffeine/aspirin (ECA) stack would boost the user’s metabolism 3% or the Clenbuterol/Cytomel T-3 stack which would boost metabolism 5-10%, DNP was seen to raise metabolism up to a relatively controlled 50% making DNP a seemingly miracle supplement. While clen/t-3, ECA, and others significantly raised the body’s temperature, DNP raised internal temperature 2-4 degrees F.
The main problem with DNP is its severe side effects. Exercise during a DNP cycle should be kept to light workouts. DNP has not been seen to cause cancer, but death is a possibility if DNP raises the user’s body temperature too high, as there is not limit to how hot DNP can make the user’s body. The lethal dose of DNP is only 4 times the dose that is effective in losing weight and fat loss.
DNP is not an appetite suppressant, so a user will be hungry, and DNP users will especially crave carbohydrates due to glucose inefficiency. Some users may be allergic, and less than 1% of women who used DNP in the 1930’s for fat reducing and weight loss developed cataracts, which led to the 1938 FDA 2,4-dinitrophenol DNP ban as a weight loss drug.
DNP since has been used off and on with scrutiny from within and outside the bodybuilding industry. Protesters of DNP note that DNP is not a forgiving chemical. Understanding what the effects, risks, and limitations of the substance are before trying to acquire and use DNP promote their hopes to deter potential DNP users, but the effectiveness of DNP to help with fat reduction and ultimately weight loss is hard to deny. A danger is the fact that DNP has a cumulative effect with a 36-hour half-life. DNP takes up to 48 hours to flush from a user’s system. Many bodybuilders adapt the “more is better” theory to their use of DNP severely increasing their risk of harmful side effects and possibly death.
Weight Loss with DNP – Scientifically Speaking
DNP accomplishes the astounding boost in metabolic rate via inhibition of the F0F1 ATP synthase molecule, located in the inner wall of each mitochondrion. While the electron transport chain still functions to pump hydrogen ions into the inter-membrane space, the coupling of the proton gradient to ATP production is rendered impossible by DNP. As a result, ATP production is dramatically reduced, and the energy is instead thrown off as heat. This results in an astounding production of heat; when using dinitrophenol, the athlete will radiate so much heat that it is uncomfortable to be within any proximity of them. Luckily, this heat does not fully contribute to body temperature increases, and is instead thrown off from the entire body surface, particularly the head. As a result, adequate doses of DNP will usually only elevate body temperature by about 1-1.5?C. This is a good thing for your central nervous system and other delicate tissues. If the heat produced by ATP contributed in a more direct matter to body temperature, effective doses for fat loss would cause body temperature increase. Nonetheless, overheating is a very real danger.
Under these conditions, much of the food that we eat could not be used for ATP synthesis and we lose weight. However, too much inhibitor and we could make too little ATP for life. The difference between weight loss and death is only a small concentration change in dinitrophenol, making the drug dangerous. Simply put, this means that while eating your normal diet, you will have somewhere between 20% and 40% reduction of calories.
Timetable of Effects and Symptoms of a DNP Cycle
DNP CYCLE Day 1 -None; possibly elevated carbohydrate cravings and/or temperature elevation.
DNP CYCLE Day 2 – T4-T3 conversion has begun to decrease; lethargy possible. Temperature should be elevated, and radiation of heat is noticeable.
DNP CYCLE Days 3-5 – Body temperature is elevated, with all the effects that one expects from DNP use. In addition, water retention usually becomes manifest here.
DNP CYCLE Days 6-10 – Definite water retention, along with other symptoms of use; user most likely feels fatter due to having “flatter” muscles (mainly the result of glycogen depletion) and holding water. Final DNP dose taken in the evening of Day 10.
DNP CYCLE Days 11-12 – DNP is clearing the system slowly. All symptoms are still present.
DNP CYCLE Days 13-14 – Water should be gone by now, or getting there. Mild diuretics will expedite this. The user will probably notice perceived greater cardiovascular and muscular endurance.
96 Hours After Final Dose – This is when someone tends to look their best. Their glycogen stores are usually compensated at this point and the retained water should be gone.
DNP exerts its effects within the cell, more specifically within the membrane of the mitochondria. The advantage of intra-cellular mechanisms of action such as this is that a tolerance to DNP cannot develop. To make a long story short, DNP makes the process of ATP formation very inefficient. Why is this important? Because ATP is the energy unit needed to drive all our biochemical reactions in our body that is necessary to keep us alive. The cells in our body constantly need energy (ATP) to stay alive. The amount of ATP needed to keep a person alive depends on his/her basal metabolic rate. By making ATP formation inefficient, a person’s basal metabolic rate can increase indefinitely, but for practical uses, basal metabolic rate can safely increase by 30-50% without putting one’s life in danger. It is not unheard of for people to lose up to one pound of pure fat per day while on DNP.
If you’re not familiar with ATP, it’s what the Calories that are stored in carbs, fats, and proteins are eventually turned into. In other words, the energy that is stored in the macro-molecules are transferred to the ATP molecule, but DNP disrupts this process. Instead of making ATP from macro-molecules in the presence of DNP, the potential energy is just turned into heat. This is very significant because ATP levels in the body will quickly diminish and cells want to replenish that storage by breaking down more fats, carbs, etc. As you can see, a patter quickly develops where ATP levels will constantly be below normal and the body will always be trying to burn more fats, carbs, and proteins to help replenish the ATP levels. This is no different than doing aerobic exercises such as jogging, biking, etc, except while on DNP, the body is doing the aerobic. Dosage is 2-6mg/1 kilo body weight .An anti allergic drug should be added to cycle.
AN IDEAL DNP CYCLE MUST CONTAIN :
– Ephedrine + Caffeine + Aspirin (to stop the appetite and for some, an energy boost)
– A good Multi Vitamin Mineral complex
– An Antioxidant Formula
– Vitamin E (Extra)
– Vitamin C (Extra)
– Ketotifen or Benadryl (To stop allergic reactions and enhance the Ephedrine)
– Herbal Support : Yohimbine HCL , Grape Seed Extract , Quercetin
– A very low carb diet prior to DNP cycle for 3-4 days. This will drain the Glycogen in the muscles and DNP will immediately start burning stored body fat.
– T-3 (Cytomel) should be added to cycle after 2-3 days because the body decreases the T-3 release as a reaction to DNP
paretomeso@protonmail.com
