Chemman's log

[chemman]

Definitely feeling better! Had some decent wood this morning. Started getting some random chubs yesterday afternoon. And these are all indications that T is on the rise. Facial hair growing faster as well. Chest hair still filling in.

I think the medrol killed my testosterone levels, which is why I felt like death again coming off the dose pack.

 

[chemman]

Figured I would make another entry in the log. Mixed feeling on my progress. I've had some spurts where I feel decent and then I will crash. Overall, I would say that things are better.

One significant change is that I have been getting better erections. I was actually able to have sex for 20 minutes without cialis a few nights ago. I lost my wood a few times but this is a vast improvement from where I was a while back. Needless to say this made my gf (and me) happy.

Body hair is definitely increasing. My gf was commenting on this yesterday. Said I looked "extra hairy." So this is a positive indication that I am experiencing an increase in androgen levels.

My joints feel a little better. I'm still getting cracking and discomfort but not as bad as before.

Mentally I am doing better. This whole ordeal has weighed very heavily on my psyche. It seems that every time I start to feel better, I crash again and I get depressed. But I'm out of bed doing things now, so it's definitely not as bad as a few month ago when I was extremely sick. Anxiety has definitely cooled off since the medrol.

I'm going to try and keep my protein intake high so that the higher T can promote some tissue repair that I desperately need.

Current supplements: vitamin D, chelated zinc, magnesium, chromium, and 20 liver tablets/day

 

[chemman]

Alright so I finally bit the bullet and bought my one week of clomiphene citrate generic @ 100mg/day. Watson Brand. Cost me 50$.

It's been two weeks since I tapered off a methylprednisolone dose pack, so I'm good to go as far as taking clomid without having my results skewed.

Next week is my last week of college and exam week. I really want to start the clomid today, but I think it could be a bad decision with all of the work I have to do. I do, however, feel like ass without the clomid, but probably functional enough to eek myself through exams and finish what has officially been the worst year of school (and everything else) in my life. My brain does not function well without testosterone.

I think that it is pretty obvious at this point that my problem is secondary hypogonadism, caused by tribulus terrestris supplements. Looking at my labs, everything looks pretty good except for my testosterone levels. The only other thing I notice is high reverse T3. All of my problems started with low testosterone (and then estradiol), so I am hoping that by correcting my root problem, everything else should fall into place. It has been over one year since I started tribulus. Clearly my HPTA is very sensitive and is not recovering very well on its own

I pray that i can tolerate clomid, otherwise it's looking like time for TRT.

 

[chemman]

And of course now I have my parents pushing antidepressants on me. Not what I'm trying to get into. Don't they lower testosterone? Or could my depression and anxiety be causing the low testosterone?

They seriously don't believe that a very low testosterone level could be causing my issues, even the physical ones. How does anxiety fuck up your joints and cause you to lose body hair?

 

[CubbieBlue]

And of course now I have my parents pushing antidepressants on me. Not what I'm trying to get into. Don't they lower testosterone? Or could my depression and anxiety be causing the low testosterone?

They seriously don't believe that a very low testosterone level could be causing my issues, even the physical ones. How does anxiety fuck up your joints and cause you to lose body hair?

Looking back on it, it looks like I might have had a panic attack. I was just sitting there completely fine and then bam.

Do you have a recent T level? (The one I can find at the beginning of this thread is ~280)

Your low t levels aren't helping anything, but I have a very strong suspicion there is a strong anxiety/depression component playing into how you feel.

Depression and anxiety can lower testosterone.

 

[chemman]

Most recent (as of a month ago) was 280ish at 8am. Just to give you an idea, my baseline when I was healthy was 590 at 1pm. We all know that T levels are higher in the morning, so my baseline is probably more like 700. So right now I'm at less than one half of where I need to be to feel right. It is clearly secondary hypogonadism. Check out my bioavailable tetosterone, it is so friggin low my gf probably has more juice floating around her system.

My cracking joints and musculoskeletal problems....clear indicators of low androgens. Loss of chest hair...low testosterone.

This all started with tribulus. I was more or less just fine before that shit. I had some depression and anxiety, so maybe I'm prone to it, but nothing that affected my life to a significant extent. And the anxiety occurred mainly when drinking loads of coffee. I had plenty of fun and hobbies, did very well in school, and was a social person. Now, it's just not the same.

Root cause...low testosterone in my books.

 

[CubbieBlue]

Most recent (as of a month ago) was 280ish at 8am. Just to give you an idea, my baseline when I was healthy was 590 at 1pm. We all know that T levels are higher in the morning, so my baseline is probably more like 700. So right now I'm at less than one half of where I need to be to feel right. It is clearly secondary hypogonadism. Check out my bioavailable tetosterone, it is so friggin low my gf probably has more juice floating around her system.

My cracking joints and musculoskeletal problems....clear indicators of low androgens. Loss of chest hair...low testosterone.

This all started with tribulus. I was more or less just fine before that shit. I had some depression and anxiety, so maybe I'm prone to it, but nothing that affected my life to a significant extent. And the anxiety occurred mainly when drinking loads of coffee. I had plenty of fun and hobbies, did very well in school, and was a social person. Now, it's just not the same.

Root cause...low testosterone in my books.

How long since the trib usage?

 

[chemman]

Started about this time last year and ended sometime in July, so about 9 months or so. I think it shut down my natural testosterone production.

 

[chemman]

Having some pretty intense anxiety, mainly upon awakening and lasting throughout the morning. I think the stress of being sick and trying to finish loads of work (multiple 20 page essays, senior thesis, tests, etc.) to graduate from college is really catching up to me. It's a bad situation, but it will be over in a few weeks, so that's the only thing maintaining my sanity right now.

Noticing even more body hair, especially on my upper chest. Joint cracking seems to be dissipating a bit. Haven't noticed it as much, but my joints do still feel yucky especially while sleeping. It feels like my bones are rubbing against each other in my shoulder joints and all in my upper back. My hips and knees do feel less "sticky," so that's an improvement.

I have read that the upper back and shoulder region has the highest androgen receptor (AR) density throughout the body. So I guess it makes sense that I am having some strange musculoskeletal issues in this area.

 

[m_ob]

Here is my old post from when I joined the board:

https://thinksteroids.com/community/threads/134278783

For those who haven't seen any of my posts, I have been going through absolute hell since this past summer.

I am 22 years old, 6'5" and 220 lbs.

I finally have a comprehensive set of labs that I want to share with all of you. Thanks in advance for your opinions.


8AM blood results from quest diagnostics

Homocysteine: 5.9 [<11.4umol/L]

Comprehensive Metabolic Panel:

Glucose: 84 [65-99 mg/dL]
Urea Nitrogen: 21 [7-25 mg/dL]
Creatinine: .78 L [o.8 -1.30 mg/dL]
BUN/creatinine ratio: 27 H (6-22 calc)
sodium:143 (135-146)
potassium: 4.6 (3.5-5.3)
chloride: 106 (98-110)
carbon dioxide: 24 (21-33)
calcium: 9.5 (8.6 - 10.2)
protein (total): 6.8 (6.2 - 8.3)
albumin: 4.5 (3.6 - 5.1)
globulin: 2.3 (2.1-3.7)
albumin/globulin ratio: 2.0 (1.0-2.1)
bilirubin: 0.4 (0.2-1.2)
alkaline phosphatase: 62 [40-115]
AST: 15 [10-40]
ALT: 20 [9-60]

Thyroid Panel
TSH: 1.97 [.4-4.5 mIU/L]
Free t4: 1.3 [0.8 - 1.8]
Free t3: 333 [ 230-420]
T3 total: 101 [76-181]
Reverse T3: 31 [11-32]
TBG: 20.3 [12.7 - 25.1]
Thyroglobulin antibodies: <20
Thyroid peroxidase antibodies: <10

VAP Choloesterol test
Total LDL-C direct: 81 [<130]
Total HDL-C Direct: 50 [>=50]
Total VLDL-C direct: 13 [<30 mg/dL]
Total cholesterol: 144 [<200]
Triglycerides: 54 [<150 mg/dL]
Total non-HDL-C: 93 [<160 mg/dL]
Total APOB100 CALC: 75 [109 mg/dL]

Remnant Lipo [IDL + VLDL3]: 10 [<30 mg/dL]


Absolute monocytes: 383 [200-950]
Absolute eosinophils: 145 [15-500]
Absolute Basophils: 17 [0-200]
neutrophils: 62.1%
lymphocytes: 31.5%
monocytes: 4.5%
eosinophils: 1.7%
basophils: 0.2%


Ferritin: 38 [20-345]
ceruloplasmin: 28 [18-36]
C-reactive protein: 0.12 [<0.80]
Prealbumin: 26 [21-43]

DHEA-S: 259 [110-510]
FSH: 4.1 [1.6-8.0]
LH: 3.0 [1.5-9.3]
progesterone: 1.1 [<1.4}

Cortisol A.M: 21.7 [4.0-22.0]
ACTH: 22

Hormones
Dihydrotestosterone: 27 [25-75 ng/dL]
Testosterone, total: 283 [250-1100 ng/dL]
Free Testosterone; 46.3 [46.0 - 224 pg/mL]
Bioavailable testosterone: 99.3 L [110 - 575]
SHBG: 23 [7-49 nmol/L]
Albumin: 4.7 [ 3.6 -5.1 g/dL]

Aldosterone: 2 [<=28 ng/dL]

CBC
White blood cell count: 8.5 [3.8-10.8 thousand/uL]
Red blood cell count 5.11 [4.20 - 5.80]
Hemoglobin: 14.9 [ 13.2-17.1]
Hematocrit: 44.4 [38.5 - 50%]
MCV: 86.9 [80.0 -100.0]
MCH: 29.3 [27.0 -33.0]
MCHC: 33.7 [32.0 - 36.0]
RDW: 13.3 [11- 15 %]
Platelet count: 260 [14- 400]
Absolute neutrophils: 5279 [1500 -7800]
Absolute lymphocytes: 2678 [850 -3900]

Celiac Disease panel
Tissue transglutaminase antibody IGA: <3 [<5 negative]
Immunoglobulin A: 252 [81 -463]
Gliadin antibody: <3 [<11 negative]
Hemoglobin A1c: 5.3 [% of total Hgb] [ <6 non-diabetic]

Vitamin D, 25-OH, total: 40 [20-100]

Gliadin antibody:4 [<11 negative]

Lyme disease c6 antibody: 0.66 [<=0.90 negative]......warrants further investigation IMO

iodine [random urine]: 198 [34-523]
Lipoprotein: 10 [<75 nmol/L]

Vitamin b12: 266 [200-1100 pg/mL]
Folate, serum: 6.4 [normal .5.4]

IGF-1: 374 [126-382]
Plasma renin activity: 0.81 [0.25 - 5.82]
c-peptide: 1.6 [0.8 -3.1]

Pending tests (quest diagnostics sucks, IMO. It's been two weeks since the blood draw)
Estradiol, ultrasensitive (they are going to perform the wrong test....we specified sensitive 13-54 on the slip)
Estrone
cortisol [free and total]
cortisol binding globulin

Current symptoms
Joint cracking and clicking and popping
Acute swelling and pain in right ankle (to the point of not being able to walk] with no trigger incident
knee pain
sciatica
lower back pain
eye floaters
anxiety {improving IMO, and mainly related to my health]
depression {same as above]
NO libido
Complete ED without cialis
muscle weakness and strength loss
numb sensations [ could be related to all the advil I take to kill the pain]
loss [ and recent return ] of chest hair
cognitive dysfunction [improving]
hypoglycemia [improving]

Current medications and supplements
vitamin D 4,000 iu/ day (after loading 12,00o iu/ day for 5 days in response to above test result)
vitamin b12 2,000 mcg/ day (started this after seeing the above test)
Fortified soy protein (started feeling better after eating this)
15 mg liquid iron/day (started after seeing above ferritin result)

you were not kidding on the shocking similarities between our biochemistry.

 

[chemman]

Yes I do believe that we have the same affliction. The parallels in thyroid function are quite shocking. Do you have a TSH from when you were healthy?

 

[hardasnails1973]

and again I can sum these cases up very easilty bilary stasis ...You do not have enough cholesterol to make hormones. Majority of your cholesterol is being used to repair your intestinal tract that is being sprayed by toxic bile, The later of cholesterol left is used to make bile it self. With all these toxins not being excreted your bile is like motor oil and your recirculatiing aound biotoxins from your gut which are just causing a huge vicous cycle. Your cholesterol is not being released from the liver probably due to your insufficent bilary flow potentially causing gall stones. Its not your gall bladder is the issue but excessive biotins from bad bacteria, enviroment toxins that resulting bile being thicken. When this happens this releases PLA2 which will release phospholipids from the cell membranes resulting in you body not having essential buiilding blocks to make hormones. Your gut will never get healed even from allergies are removed because you keep reciruclating toxic bile because it like motor oil. You needs an oil change so to speak. I have been researching this stuff for over 6 years and the bilary tree is a huge factor in this as I have consulted with one of the best ND I have came across about issues dealing with epidemic low cholesterol levels which are likely not genetic but more so environmental induced, or from pathogenic bacteria in the system. NO matter how much probiotics you take it will not sticked to an inflammed intestinal tract that is keep getting infected by rancid bile acids not being recycled properly. Bile gets recycles and if that bile is filled with endo or exto biotins that never get released you are going to end up in a vicious cycle never getting better. One needs to break this cycle. This may explain why people with low cholesterol are most likely suspected of allergies, gut inflammtion, small bacteria overgrowths, heavy metals because they can not unload the toxins.

 

[m_ob]

and again I can sum these cases up very easilty bilary stasis ...You do not have enough cholesterol to make hormones. Majority of your cholesterol is being used to repair your intestinal tract that is being sprayed by toxic bile, The later of cholesterol left is used to make bile it self. With all these toxins not being excreted your bile is like motor oil and your recirculatiing aound biotoxins from your gut which are just causing a huge vicous cycle. Your cholesterol is not being released from the liver probably due to your insufficent bilary flow potentially causing gall stones. Its not your gall bladder is the issue but excessive biotins from bad bacteria, enviroment toxins that resulting bile being thicken. When this happens this releases PLA2 which will release phospholipids from the cell membranes resulting in you body not having essential buiilding blocks to make hormones. Your gut will never get healed even from allergies are removed because you keep reciruclating toxic bile because it like motor oil. You needs an oil change so to speak. I have been researching this stuff for over 6 years and the bilary tree is a huge factor in this as I have consulted with one of the best ND I have came across about issues dealing with epidemic low cholesterol levels which are likely not genetic but more so environmental induced, or from pathogenic bacteria in the system. NO matter how much probiotics you take it will not sticked to an inflammed intestinal tract that is keep getting infected by rancid bile acids not being recycled properly. Bile gets recycles and if that bile is filled with endo or exto biotins that never get released you are going to end up in a vicious cycle never getting better. One needs to break this cycle. This may explain why people with low cholesterol are most likely suspected of allergies, gut inflammtion, small bacteria overgrowths, heavy metals because they can not unload the toxins.

Hans.. one problem with this theory. Our LH and FSH are low, not just testosterone. Cholesterol has no effect at all on the gonadtropins, just the production of the actual hormone testosterone. Thanks for trying, but I think the answer is far simpler than, toxins, pathogenic bacteria, and gut inflammation, as easy as that is to pin it as.

 

[hardasnails1973]

Hans.. one problem with this theory. Our LH and FSH are low, not just testosterone. Cholesterol has no effect at all on the gonadtropins, just the production of the actual hormone testosterone. Thanks for trying, but I think the answer is far simpler than, toxins, pathogenic bacteria, and gut inflammation, as easy as that is to pin it as.

Nope it is all interlinked. The substance that is released from saffects the LH..
You like to research ..I know the answer and if I would have known this 6 years ago I would not be on HRT today. I have seen this trend occur in many young guys with low LH and low cholesterol. Bigpete757 had the same thing, but since he was premature to jump to other conclusions which this was evident in his profile, mine , and other young guys profile as well. I think after about 6 months - year you might be able to find connection. I had client that had the same exact profile of you and I jumped his levels up to 700 in less then 8 weeks. He was one of my greatest accomplishments. He was actually on TRT for 2 years from crisler and he came off 8 weeks retested at 200 then 8 weeks with out clomid I got him restarted by manpulating his food combination and very little supplementation. This is medical documented in his medical records which legal documents..I am now actually using this approach as first wave to stimulate people that fall into this profile with low cholesterol. I am pushing nutritent intervention to a whole new level.

 

[chemman]

Since my testosterone is wicked low, but my pituitary is not asking for more testosterone via LH and FSH, I am concluding that the problem lies in the HPTA.

 

[m_ob]

Many dubious practitioners claim that food allergies may be responsible for virtually any symptom a person can have. In support of this claim—which is false—they administer various tests purported to identify offending foods. Claims of this type may seem credible because about 25% of people think they are allergic to foods. However, scientific studies have found that only about 6% of children and 1-2% of adults actually have a food allergy, and most people with food allergies are allergic to less than four foods .
When we think of allergies, we immediately think of an allergy whose symptoms occur within minutes of ingesting a food or chemical. The symptoms include hives and itching. . . .

Although the ELISA/ACT test can assess the levels of certain immune responses, these are not necessarily related to allergy and have nothing whatsoever to do with a person's need for supplements. Moreover, many of the symptoms listed in SPL's brochure are unrelated to allergy and are not appropriately treated with supplement products.

Other food immune complex and IgG tests, which assess immune reactions that are common but not necessarily related to allergy

Nambudripad's Allergy Elimination Technique (NAET), based on the notion that allergies are caused by "energy blockage" that can be diagnosed with muscle-testing and permanently cured with acupressure and/or acupuncture treatments.

The correct way to assess a suspected food allergy or intolerance is to begin with a careful record of food intake and symptoms over a period of several weeks. Symptoms such as swollen lips or eyes, hives, or skin rash may be allergy-related, particularly if they occur within a few minutes (up to two hours) after eating. Diarrhea may be related to a food intolerance. Vague symptoms such as dizziness, weakness, or fatigue are not food-related. The history-taking procedure should note the suspected foods, the amounts consumed, the length of time between ingestion and symptoms, whether there is a consistent pattern of symptoms after the food is consumed, and several other factors. Although nearly any food can cause an allergic reaction, a few foods account for about 90% of reactions. Among adults these foods are peanuts, nuts, fish, and shellfish. Among children, they are egg, milk, peanuts, soy, and wheat .

If significant symptoms occur, the next step should be to see whether avoiding suspected foods for several weeks prevents possible allergy-related symptoms from recurring. If so, the suspected foods could be reintroduced one at a time to see whether symptoms can be reproduced. However, if the symptoms include hives, vomiting, swollen throat, wheezing, or other difficulty in breathing, continued self-testing could be dangerous, so an allergist should be consulted.

Proper medical evaluation—done best by an allergist—will include careful review of your history and skin testing with food extracts (using a prick or puncture technique) to see whether an allergic mechanism is involved in your symptoms. In cases where skin testing might be dangerous, a radioactive allergy sensitivity test (RAST) may be appropriate. The RAST is a laboratory test in which the technician mixes a sample of the patient's blood with various food extracts to see whether antibodies to food proteins are present in the blood. It is not as reliable as skin testing and is more expensive. A negative prick or RAST test indicates a low probability of allergy to the test substance. Positive tests, however, have much less predictive value .

The only sure way to diagnose an allergy to a suspected food, food coloring, or other additive is challenge testing in which the patient ingests either the suspected food or a placebo . This may be appropriate if the patient's history suggests a food allergy but the skin or RAST tests are negative. Because dangerous reactions can occur, challenge testing should be done in a hospital or office that is specially equipped for that purpose.

Aetna Policy Coverage Policy Bulletin 0038. Allergy Testing and Allergy Immunotherapy

BlueCross BlueShield of Tennessee Medical Policy Manual

University of Iowa Virtual Hospital: Food allergy basics

Sicherer SH. Manifestations of food allergy: Evaluation and management. American Family Physician 59:415-424, 1999.

American Academy of Allergy: Position statements—Controversial techniques. Journal of Allergy and Clinical Immunology 67:333-338, 1980. Reaffirmed in 1984.

Chambers VV and others. A study of the reactions of human polymorphonuclear leukocytes to various antigens. Journal of Allergy 29:93-102, 1958.

Benson TE, Arkins JA. Cytotoxic testing for food allergy: Evaluations of reproducibility and correlation. Journal of Allergy and Clinical Immunology 58:471-476, 1976.

Lehman CW. The leukocytic food allergy test: A study of its reliability and reproducibility. Effect of diet and sublingual food drops on this test. A double-blind study of sublingual provocative food testing: A study of its efficacy. Annals of Allergy 45:150-158, 1980.

Proposed notice: Medicare program; Exclusion from Medicare coverage of certain food allergy tests and treatments. Federal Register 48(162):37716-37718, 1983.

British Advertising Standards Organization. Adjudication: Allergy Testing Service, May 1999.

Sampson HA. Food allergy. JAMA 278:1888-1894, 1997.


Latex Allergy, 9/2/2001
Latex Allergy
The Latex Allergy Epidemic

Some have even been forced to terminate their careers for this reason. Medical and dental procedures on sensitized individuals may be complicated by anaphylactic events, as may the use of latex pacifiers by infants. The FDA has received more than 2000 reports of injury and several reports of death associated with latex allergy.

The surge of latex allergy among health-care workers is primarily attributable to greater use of disposable gloves to prevent the spread of AIDS and hepatitis B. Increased demand and cost pressures for gloves has led some manufacturers to shorten the manufacturing time by reducing the number of washing and purifying steps, which increases the amount of sensitizing protein that the gloves will transmit.

The American College of Allergy, Asthma, and Immunology has published guidelines and recommends that people who have been diagnosed as allergic wear an identification card (or bracelet) and a self-injectable adrenalin device. Sensitive individuals should be sure that their health-care providers are aware of their condition so that they are not exposed to latex during medical procedures or surgery. A few states have introduced bills to ban the use of powdered latex gloves in medical facilities.

American College of Allergy, Asthma, and Immunology Latex Allergy Home Page

The Education for Latex Allergy / Support Team & Information Coalition (Elastic) maintains a comprehensive list of Internet sites with information related to latex allergy.

Latex Allergy Links

Occupational Safety & Health Administration (OSHA) Latex Allergy Page

Potential for allergy to natural rubber latex gloves and other natural rubber products. OSHA Technical Information Bulletin, April 1999.

 

[m_ob]

Nope it is all interlinked. The substance that is released from PLA2 stimulates affects the LH..
You like to research ..I know the answer and if I would have known this 6 years ago I would not be on HRT today. I have seen this trend occur in many young guys with low LH and low cholesterol. Bigpete757 had the same thing, but since he was premature to jump to other conclusions which this was evident in his profile, mine , and other young guys profile as well

Phospholipases A2 (PLA2s) EC 3.1.1.4 are enzymes that release fatty acids from the second carbon group of glycerol. This particular phospholipase specifically recognizes the sn-2 acyl bond of phospholipids and catalytically hydrolyzes the bond releasing arachidonic acid and lysophospholipids. Upon downstream modification by cyclooxygenases, arachidonic acid is modified into active compounds called eicosanoids. Eicosanoids include prostaglandins and leukotrienes, which are categorized as inflammatory mediators.[1]

PLA2 are commonly found in mammalian tissues as well as insect and snake venom.[2] Venom from both snakes and insects is largely composed of melittin, which is a stimulant of PLA2. Due to the increased presence and activity of PLA2 resulting from a snake or insect bite, arachidonic acid is released from the phospholipid membrane disproportionately. As a result, inflammation and pain occur at the site.[3] There are also prokaryotic A2 phospholipases.

Additional types of phospholipases include phospholipase A1, phospholipase B, phospholipase C, and phospholipase D.

It doesn't add up, how is snake venom poisoning my LH levels?

 

[hardasnails1973]

The answer is staring right at you right under neath your nose...So close yet so far...

i'm actually going to try to come off cortef again once i back fill metabolic gaps and dig into the gut deeper to remove the inflammation. I suspect most adrenal insufficent people have hidden inflammation with in the gut once this is removed adrenals should fire back up.. I talked to an ND at gret extense of this and she agrees 100% the body will kick back in.

 

[CubbieBlue]

The answer is staring right at you right under neath your nose...So close yet so far...

i'm actually going to try to come off cortef again once i back fill metabolic gaps and dig into the gut deeper to remove the inflammation. I suspect most adrenal insufficent people have hidden inflammation with in the gut once this is removed adrenals should fire back up.. I talked to an ND at gret extense of this and she agrees 100% the body will kick back in.

So how do you change the "engine oil" so to speak?

 

[hardasnails1973]

Thin the bile...botanicals can be used as so can sam-e, TMG.

Let me put it this way

If you have all this shit ( drugs, environmental toxins, deactivated hormone,endo toxins from the bowels, carcinagens ) is being processed by the liver and it can not get out because the door is partially shut what do you think would be the reprocussion?

When your car runs oil gets dirty your car runs like shit because the oil is dirty and thick,,Same thing happens to your body with bile