vorcellian
New Member
Where can we get peptides and bacteriostatic water in the EU?
MESO-Rx
Anabolic Steroids
EU domestic source talk
- Thread starter Sampei
- Start date
Plenty of places, I'll give you few website I tried lately, when I get off work. Can't say much for the quality of peptides, I only use pt141 but the bacteriostatic works well.
BK2THEFUTURE
Member
It is not carcinogenic. Its actually the opposite. Dont spread lies
BK2THEFUTURE
Member
No no no. It doesn't cause cancer from the oxidative stress. especially considering it helps reduces the oxidative stress on the mitochondria
M. Tugboat
Well-known Member
Because people who take AAS only use testosterone, right?
Is there a TRT version of Tren? MENT maybe? How about the toxic as shit Superdrol? Or "your lipids will crush harder than the economy" Anavar?
Get off your high horse with that bullshit.
M. Tugboat
Well-known Member
A time-released version of DNP is under development as a cure for liver disease and diabetes. The Shulman group at Yale is currently developing a low toxicity time-released version of radical fat burner and mitochondrial decoupler DNP as a means of altogether reversing Type II diabetes and liver disease.
Science Magazine, Yale University https://blogs.sciencemag.org/pipeline/archives/2015/03/03/dinitrophenol_a_possible_comeback
"Metabolic uncoupling is a promising diabetes therapy. The idea is that your mitochondria will plow though large amounts of lipids under these conditions, and there’s plenty of evidence that knocking down free fatty acids and tissue lipid stores would be of great benefit for Type II patients. The problem is that this therapy has a well-deserved reputation for having a low therapeutic index."
"2,4-dinitrophenol is a pretty unlikely-looking drug, but it most certainly has metabolic effects. It was on the market for a while many decades ago as a weight-loss therapy, and no one can say that it won’t make you lose weight. The danger is that you lose it all the way down to your dry bone mass, because it doesn’t take much extra DNP to give you dangerous amounts of overheating and perhaps even a critical shortage of ATP, which frivolous organs like your heart and brain seem to have become dependent on."
"This formulation does a dramatic job of reversing diabetes symptoms in rodent models, and fatty liver disease as well. Shulman is working on taking this toward human clinical trials, and the animal results make a good case."
Banned weight-loss drug could combat liver disease, diabetes
Controlled-release mitochondrial protonophore reverses diabetes and steatohepatitis in rats
Contra widespread misconception, DNP decreases oxidative stress, rather than increased ROX, and increased maximum lifespan in rats.
Mitochondrial uncoupling evolved as a protective mechanism against the excessive production of damaging reactive oxygen species (ROS).
The mitochondrial uncoupler 2,4‐dinitrophenol attenuates tissue damage and improves mitochondrial homeostasis following transient focal cerebral ischemia
DNP as Powerful Antioxidant
DNP decreases oxidative stress, as demonstrated in the following study.
Mild mitochondrial uncoupling in mice affects energy metabolism, redox balance and longevity
"Treatment of mice with low doses of the protonophore 2,4‐dinitrophenol promotes enhanced tissue respiratory rates, improved serological glucose, triglyceride and insulin levels, decrease of reactive oxygen species levels and tissue DNA and protein oxidation as well as reduced body weight."
Uncoupling protects against ROS
Mitochondrial uncoupling as a regulator of life-history trajectories in birds: an experimental study in the zebra finch
"Mitochondria have a fundamental role in the transduction of energy from food into ATP. The coupling between food oxidation and ATP production is never perfect, but may nevertheless be of evolutionary significance. The ‘uncoupling to survive’ hypothesis suggests that ‘mild’ mitochondrial uncoupling evolved as a protective mechanism against the excessive production of damaging reactive oxygen species (ROS)."
2,4 Dinitrophenol as Medicine
"DNP appears to mimic in part the neuroprotective and neurorestorative effects of exercise and fasting by increasing BDNF, lowering cellular stress and building cellular resiliency by mild increases in mitochondrial bioenergetics."
"If ROS production were managed, could disease onset due to aging be delayed or prevented? Is it possible that most, if not all neurodegenerative diseases are manifested through mitochondrial dysfunction?"
"It is known that mitochondrial uncouplers specifically target the entire organelle’s physiology non-genomically. Unexpected drug findings will be discussed, such as DNP’s induction of neurotrophic growth factors involved in neuronal health, learning and cognition."
Neuroprotective actions of 2,4-dinitrophenol
Cancer Treatment
2,4-Dinitrophenol raises body temperature by forcing the cells of the human body to create ATP less efficiently from glucose. Cancer cells have almost 200× output of ATP and work overtime in doing so. When stimulated by the DNP their mitochondria will act like a little furnace creating the demise of the cancer cell well before the healthy cells die from the DNP.
Effects of 2,4-Dinitrophenol and Other Metabolic Inhibitors on the Bidirectional Carrier Fluxes, Net Transport, and Intracellular Binding of Methotrexate in Ehrlich Ascites Tumor Cells
Effect of DNP on wild type and chemoresistant colorectal cancer cells
2,4-dinitrophenol induces G1 phase arrest and apoptosis in human pulmonary adenocarcinoma Calu-6 cells
The Metabolism of Neoplastic Tissues: The Effect of 2:4-Dinitrophenol on the Respiration of Ascites Tumour Cells
Science Magazine, Yale University https://blogs.sciencemag.org/pipeline/archives/2015/03/03/dinitrophenol_a_possible_comeback
"Metabolic uncoupling is a promising diabetes therapy. The idea is that your mitochondria will plow though large amounts of lipids under these conditions, and there’s plenty of evidence that knocking down free fatty acids and tissue lipid stores would be of great benefit for Type II patients. The problem is that this therapy has a well-deserved reputation for having a low therapeutic index."
"2,4-dinitrophenol is a pretty unlikely-looking drug, but it most certainly has metabolic effects. It was on the market for a while many decades ago as a weight-loss therapy, and no one can say that it won’t make you lose weight. The danger is that you lose it all the way down to your dry bone mass, because it doesn’t take much extra DNP to give you dangerous amounts of overheating and perhaps even a critical shortage of ATP, which frivolous organs like your heart and brain seem to have become dependent on."
"This formulation does a dramatic job of reversing diabetes symptoms in rodent models, and fatty liver disease as well. Shulman is working on taking this toward human clinical trials, and the animal results make a good case."
Banned weight-loss drug could combat liver disease, diabetes
Controlled-release mitochondrial protonophore reverses diabetes and steatohepatitis in rats
Contra widespread misconception, DNP decreases oxidative stress, rather than increased ROX, and increased maximum lifespan in rats.
Mitochondrial uncoupling evolved as a protective mechanism against the excessive production of damaging reactive oxygen species (ROS).
The mitochondrial uncoupler 2,4‐dinitrophenol attenuates tissue damage and improves mitochondrial homeostasis following transient focal cerebral ischemia
DNP as Powerful Antioxidant
DNP decreases oxidative stress, as demonstrated in the following study.
Mild mitochondrial uncoupling in mice affects energy metabolism, redox balance and longevity
"Treatment of mice with low doses of the protonophore 2,4‐dinitrophenol promotes enhanced tissue respiratory rates, improved serological glucose, triglyceride and insulin levels, decrease of reactive oxygen species levels and tissue DNA and protein oxidation as well as reduced body weight."
Uncoupling protects against ROS
Mitochondrial uncoupling as a regulator of life-history trajectories in birds: an experimental study in the zebra finch
"Mitochondria have a fundamental role in the transduction of energy from food into ATP. The coupling between food oxidation and ATP production is never perfect, but may nevertheless be of evolutionary significance. The ‘uncoupling to survive’ hypothesis suggests that ‘mild’ mitochondrial uncoupling evolved as a protective mechanism against the excessive production of damaging reactive oxygen species (ROS)."
2,4 Dinitrophenol as Medicine
"DNP appears to mimic in part the neuroprotective and neurorestorative effects of exercise and fasting by increasing BDNF, lowering cellular stress and building cellular resiliency by mild increases in mitochondrial bioenergetics."
"If ROS production were managed, could disease onset due to aging be delayed or prevented? Is it possible that most, if not all neurodegenerative diseases are manifested through mitochondrial dysfunction?"
"It is known that mitochondrial uncouplers specifically target the entire organelle’s physiology non-genomically. Unexpected drug findings will be discussed, such as DNP’s induction of neurotrophic growth factors involved in neuronal health, learning and cognition."
Neuroprotective actions of 2,4-dinitrophenol
Cancer Treatment
2,4-Dinitrophenol raises body temperature by forcing the cells of the human body to create ATP less efficiently from glucose. Cancer cells have almost 200× output of ATP and work overtime in doing so. When stimulated by the DNP their mitochondria will act like a little furnace creating the demise of the cancer cell well before the healthy cells die from the DNP.
Effects of 2,4-Dinitrophenol and Other Metabolic Inhibitors on the Bidirectional Carrier Fluxes, Net Transport, and Intracellular Binding of Methotrexate in Ehrlich Ascites Tumor Cells
Effect of DNP on wild type and chemoresistant colorectal cancer cells
2,4-dinitrophenol induces G1 phase arrest and apoptosis in human pulmonary adenocarcinoma Calu-6 cells
The Metabolism of Neoplastic Tissues: The Effect of 2:4-Dinitrophenol on the Respiration of Ascites Tumour Cells
M. Tugboat
Well-known Member
There's also a "light" version of DNP called BAM15 if anyone is interested, but I dont know how available it is.
M. Tugboat
Well-known Member
I am sorry if I came too strong, I didn't want to offend you, make you feel bad or anything, it's just that we're all injecting Chinese chemicals into our bodies, there no need to judge and look down on each other.
M. Tugboat
Well-known Member
@scientifik as M@NU (who I can't tag for some reason) you still haven't posted any links/sources at all.
Until you do post something, your words hold as much weight as the feelz reports when it comes to AAS purity.
Until you do post something, your words hold as much weight as the feelz reports when it comes to AAS purity.
M. Tugboat
Well-known Member
Would you mind posting them here too? I want some bpc 157 and healing peptides in general, but seems trickier than finding a steroids source.
scientifik
Member
Lol u posted one study 50 years old and other in VITRO. I told you don't post every study you find on Google if you don't know what they say and how extrapolate data. Have a nice Sunday to everyone.
scientifik
Member
You need to post me study on human, not that bullshit in VITRO. You know if I pee on some cancer cells in a glass vial they die wow now urine is anticancer ahahahahah geez man u
ItsDaBoii
Well-known Member
Liska has bpc 157
scientifik
Member
Lol they are useless unless you use human peptides analogue. Hard to find and pricey, u need permission and paper statements. It's like the igf diatriba. The only one that works is Recombinant Human IGF-1 which costs lot of money and really hard to get unless as I said you have a laboratory, or you work/study in the bio sector. Gg
GuerillaPete
Well-known Member
Yeah those studies bug me out !Every day in see them orange kills cancer , grapefruit kills cancer every fucking thing kills cancer and when you click on the article it said in vitro. Fucking click bait shit .
scientifik
Member
Yes, that's why I said you need to extrapolate data and read carefully. Internet is a good place if you know how to filter things.
M. Tugboat
Well-known Member
And you still haven't posted anything at all
M. Tugboat
Well-known Member
Has anyone tested it?
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