Experienced gh users question.

In my estimation from user feedback here, no clear correlation between GH side effects and two things: 1) pharma vs UGL; and 2) dimer content.

But these are the first things everyone turns to.

In my opinion and experience, more reasonable explanations are: 1) dose; and 2) lifestyle (diet, hydration, cardio, & sleep).
So I have no experience with pharma but with the UGL gh, Im not sure if I’m allowed to name a UGL source on this board but they carry gray tops and black tops. I used the black tops which were cheaper for a while and got horrible cts, bloating, exhausted, etc. Switched to gray tops and most of that went away. I ran out of gray tops recently and went right back to the black tops and all the horrible sides came back, went to the grays and they went away again. Both lines tested with relatively no dimer and very pure. Im not sure what causes the difference but there was a pretty big one

Edit: I did go back and check labs on the black tops and they were tested in 2023, before jano updated his gh testing to be more sensitive to dimer so they could definitely contain some. The gray tops were tested april 2024 with 0 dimer so I guess that could be the key, but then again I’ve been told pharma gh is allowed to have a specific amount of dimer as well
 
Take extended releases tablet and start from 1000mg a day.

To me Metformin didn't keep BG low enough, GLP1 instead did the job.

Tried only semaglutide for now and at 1mg a week I had perfect BG on 4IU of HGH.

I'm increasing to 10IU soon and switched to tirz probably gonna use 5mg a week, we will see how it goes with the BG
 
Take extended releases tablet and start from 1000mg a day.

To me Metformin didn't keep BG low enough, GLP1 instead did the job.

Tried only semaglutide for now and at 1mg a week I had perfect BG on 4IU of HGH.

I'm increasing to 10IU soon and switched to tirz probably gonna use 5mg a week, we will see how it goes with the BG
what were your fasting BG numbers? Are you still doing cardio, and what is your diet?
Curious to this as I am on 4iu and just use berberine and other GDA's and do daily fasted cardio (30min LISS) and lower carb diet. My BG and A1c are good, but it would be nice to eat more carbs and do less cardio (3 times a week) and not have negative impact to BG numbers.
If sema or tirz made it easier for me with just one or two shots a week id switch
 
what were your fasting BG numbers? Are you still doing cardio, and what is your diet?
Curious to this as I am on 4iu and just use berberine and other GDA's and do daily fasted cardio (30min LISS) and lower carb diet. My BG and A1c are good, but it would be nice to eat more carbs and do less cardio (3 times a week) and not have negative impact to BG numbers.
If sema or tirz made it easier for me with just one or two shots a week id switch
Fasting BG number on Metformin 95-100 depends on the day and I had to not take the GH the night before drawing blood.
On 1500-2000 ER Metformin.

On semaglutide 1mg a week
I got 76-80 maximum fasting BG.

I don't do cardio (yes I know...)
My diet is a fairly normal high protein, medium fat and carbs.

I don't eat more then 200gr of carb on average, on many days even lower than that.

I switched to tirz now and just started it, so we will see if at 5mg a week it will work the same, I'm increasing HGH dosage tho... So who knows.
 
Fasting BG number on Metformin 95-100 depends on the day and I had to not take the GH the night before drawing blood.
On 1500-2000 ER Metformin.

On semaglutide 1mg a week
I got 76-80 maximum fasting BG.

I don't do cardio (yes I know...)
My diet is a fairly normal high protein, medium fat and carbs.

I don't eat more then 200gr of carb on average, on many days even lower than that.

I switched to tirz now and just started it, so we will see if at 5mg a week it will work the same, I'm increasing HGH dosage tho... So who knows.
good to know. I am just looking at bg management from the GLP so I would probably stick with cheaper sema over tirz. I really dont want appetite suppresion or any other benefits that may come from tirz.
 
good to know. I am just looking at bg management from the GLP so I would probably stick with cheaper sema over tirz. I really dont want appetite suppresion or any other benefits that may come from tirz.
sema has stronger and worse appetite suppression than tirz.

2.5mg of tirz a week for BG control may be sufficient, however I do not think many of us truly need additional BG control for the amount of GH we do. getting an A1C may be a good test
 
I
I second this notion. Can anybody share their Metformin protocol?
I take 500mg xr right before bed. Currently on 4iu, will bump it up to six if bloods look good at the beginning of the month. On the 27th of last month fbg was 92 and a1c was 5.2.
 
sema has stronger and worse appetite suppression than tirz.

2.5mg of tirz a week for BG control may be sufficient, however I do not think many of us truly need additional BG control for the amount of GH we do. getting an A1C may be a good test
My A1c is 4.6 so I am good and thats on 4iu of GH. Just would be nice to eat more carbs and not do daily cardio. I dont feel like I will go over 4iu, but if that is the case I may try Tirz instead of sema, was hoping for sema as it is cheaper.
 
good to know. I am just looking at bg management from the GLP so I would probably stick with cheaper sema over tirz. I really dont want appetite suppresion or any other benefits that may come from tirz.
Appetite suppression from sema is stronger than tirz, but the effect will wear down with time easily if you don't increase the dosage; and as you just need it for BG control there will no problem with either of them.

Sema Is cheaper so yeah I would stick with it, even so many ppl report tiredness with it so maybe if you get that tirz can be a good alternative.
 
sema has stronger and worse appetite suppression than tirz.

2.5mg of tirz a week for BG control may be sufficient, however I do not think many of us truly need additional BG control for the amount of GH we do. getting an A1C may be a good test

Another member reported A1c creep from 5.1 to 5.6 on 2-3 IU hGH/d. Not particularly worrying except they also had a family history of type 2 diabetes.

GH-induced insulin resistance may be readily reversible upon cessation of GH but if it isn't absolutely necessary to reach your goals, I'd consider discontinuing GH or other blood glucose management options.

Personally, I'm not worried about GH-induced IR. I don't have a sense that it's like diabetic pathological IR. We're not walking around with blood glucose in the 300's or worse.
 
It's none of my business but you should still do cardio anyway. Benefits go far beyond blood glucose control.
correct, but from medical perspective I thought it was recommended like 2 hours a week of zone 2 Liss. Id be cool with 3 to 4 times a week 30 minute zone 2 liss vs everday which I am doing now.
 
I do not understand all of that "zone" stuff. It seems like going harder would be better from a health perspective, but that is just me. I tend to push way harder than zone 2.

Zone 2 is 60-70% of max heart rate.

max heart rate, 220-age (57) = 163

163 x .6 = 97.8
163 x .7 = 114.1

That is laughable.

I try to spend an extended time over 140, although it takes a while to get there. I am usually over 150 by the end, and I am closer to 60 than 50. My cardio is 30-45 minutes, usually toward the shorter end because I am a busy guy,
 
I do not understand all of that "zone" stuff. It seems like going harder would be better from a health perspective, but that is just me. I tend to push way harder than zone 2.

Zone 2 is 60-70% of max heart rate.

max heart rate, 220-age (57) = 163

163 x .6 = 97.8
163 x .7 = 114.1

That is laughable.

I try to spend an extended time over 140, although it takes a while to get there. I am usually over 150 by the end, and I am closer to 60 than 50. My cardio is 30-45 minutes, usually toward the shorter end because I am a busy guy,
Me doing zero cardio and envying you guys that are so disciplined in doing it :(
 
Metformin lowers IGF-1 significantly. So does Berberine. I'm looking for other ways to increase insulin-sensitivity while on GH. Perhaps some retatrutide. Dont know if that also lowers IGF-1 though, but I highly doubt it. Will be doing more research in the next couple weeks.
 
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