Hair Loss

Man, I f'd up my regimen. Tren maybe did something. Hair thinned to mf. I suffer from MPB though.

Start:-
2% Minox: 9th September 2019.
5% Minox: 12th January 2020.
Ketoconazole: 15th Sep.
Finasteride: 20th Sep.

Originally planed to start 5% in October. Well, I just started it now! Missed so many damn days in Nov/Dec!

Here is how Jan is going.

1= 1 application of minox.
Keto= Using Ketoconazole to shampoo.

January:-

1st: 1mg Fin.
2nd: 1mg Fin.
3rd: 1mg Fin.
4th: ----------
5th: 1mg Fin.
6th: 1mg Fin.
7th: 0.5mg Fin.
8th: 0.5mg Fin.
9th: 0.5mg Fin.
10th: 0.5mg Fin.
11th: 0.5mg Fin.
12th: 1. 0.5mg Fin.
13th: 1. 0.5mg Fin.
14th: Keto. 0.5mg Fin.
15th: 1. 0.5mg Fin.
16th: 0.5mg Fin.
17th: 1. 0.5mg Fin.

Guess what? I'm gonna add Hydrocort 1% e3d in my regimen. Yes. Yes, I'll so don't stop me.
 
Man, I f'd up my regimen. Tren maybe did something. Hair thinned to mf. I suffer from MPB though.

Start:-
2% Minox: 9th September 2019.
5% Minox: 12th January 2020.
Ketoconazole: 15th Sep.
Finasteride: 20th Sep.

Originally planed to start 5% in October. Well, I just started it now! Missed so many damn days in Nov/Dec!

Here is how Jan is going.

1= 1 application of minox.
Keto= Using Ketoconazole to shampoo.

January:-

1st: 1mg Fin.
2nd: 1mg Fin.
3rd: 1mg Fin.
4th: ----------
5th: 1mg Fin.
6th: 1mg Fin.
7th: 0.5mg Fin.
8th: 0.5mg Fin.
9th: 0.5mg Fin.
10th: 0.5mg Fin.
11th: 0.5mg Fin.
12th: 1. 0.5mg Fin.
13th: 1. 0.5mg Fin.
14th: Keto. 0.5mg Fin.
15th: 1. 0.5mg Fin.
16th: 0.5mg Fin.
17th: 1. 0.5mg Fin.

Guess what? I'm gonna add Hydrocort 1% e3d in my regimen. Yes. Yes, I'll so don't stop me.

My hair lost stack which ive been getting massive regrowth from. Hair looks better than it has in 4 years.


Every Day:
Minox 5% With 30mg Of RU58841 Suspended in it

Monday: Dutasteride .5
Tuesday: Finasteride 1mg
Wednesday: Dutasteride .5
Thursday: Finasteride 1mg
Friday:Dutasteride .5

Finasteride alone is not strong enough to combat my hair loss at all. Tried it for months. Wasnt until i added Dutasteride 3 Months ago that i started to Finally shed and since then My hair has Thicken like CRAZY!!!

Minox and RU i use 7 days a week.
Minox to as a growth agonist and RU to handle the Additional Androgens in the scalp.
Ive taken RU in the past plenty of times and it has worked. But this is my first with Minox which is also working. Been using Minox for a month now.

Im always getting complements on my hair and how much it has thickened up. Started to happen a bit after Addint Dutas but minox i know will take it to another level!
 
For me, Finasteride works. Thicker hair and shiny good looking.

I've dropped to .5 because it's 90%+ as good as 1mg.

Keeping an eye on my head for next 3 to 4 months now. Natty life results, I wanna see! Cycling f'd my hair. 2 cycles last year, bridged with PCT. Tren added and it thinned out my hair, specially during 80mg ed injections.

Now, stable natty test levels, stable, hopefully, hormones should improve hair density, maybe even regrowth on temples, which I'M LOOKING FOR!
 
but what happens when you stop taking these substances. Does hair growth/thickness decrease below the rate prior to taking them.
 
A few years ago I was totally going to start hair loss prevention stuff prior to cycling because of the MPB in the family. No clue why but for some reason I had assumed it shouldn't be too bad so I did nothing and cycled anyway. I'm not joking it reduced my hair down to around 30-40% left on the top lmao

It was to a point where I just gave up and said fuck it and that was it. Ended up buzzing it right down and never looked back

So if you want to keep your hair don't do like I did lolol
 
Been on fina for almost a year (TRT was accelerating MPB, but brought everything and some back within 9 months) and haven’t noticed anything as far as strength loss. I wasn’t aware of any correlation between the two.

I was on dutasteride for a while and after a while my strength tanked which is the reason I came off it.
 
A few years ago I was totally going to start hair loss prevention stuff prior to cycling because of the MPB in the family. No clue why but for some reason I had assumed it shouldn't be too bad so I did nothing and cycled anyway. I'm not joking it reduced my hair down to around 30-40% left on the top lmao

It was to a point where I just gave up and said fuck it and that was it. Ended up buzzing it right down and never looked back

So if you want to keep your hair don't do like I did lolol

Yeah I did the same. Trying to salvage what I got left. The thinned hair makes me look like 20 years older than I am, but I do not look good bald. Don't have the proper head shape for it imo
 
Yeah I did the same. Trying to salvage what I got left. The thinned hair makes me look like 20 years older than I am, but I do not look good bald. Don't have the proper head shape for it imo

I have the head shape for it but when i buzz down or shave it off i look like a complete peace of shit person. VS When i have hair i look more approachable and have better odds in the corporate world if i ever go that route.
 
Yeah I did the same. Trying to salvage what I got left. The thinned hair makes me look like 20 years older than I am, but I do not look good bald. Don't have the proper head shape for it imo

Oh I totally understand where you're coming from and don't blame you for trying to maintain or even improve what you have. Honestly, for me personally it just didn't seem worth the effort spending the time and $$

Some guys just become hat guys lol


I have the head shape for it but when i buzz down or shave it off i look like a complete peace of shit person. VS When i have hair i look more approachable and have better odds in the corporate world if i ever go that route.

I understand what you're saying and do feel I was more approachable with hair than without
 
Rub Ozzie (must be low-temp Australian) Emu oil into your scalp at night. Uniquely, it penetrates all the skin layers and is a strong 5-AR inhibitor, and it forms depots and dwells in the skin and hair follicles all day, even after a morning shampoo

It also grows hair in its own right, some say better than minoxidil. It also re-activates LONG miniaturized frontal hair follicles, something minoxidil cannot do (for unknown reasons)
 
Alopecia Areata Due to Isotretinoin Treatment

Isotretinoin is a safe and useful medication for acne management. Adverse effects are mostly related to cutaneous and mucous membranes. We present a case of a 24-year-old female patient who was on treatment with Isotretinoin for acne vulgaris grade 4. After 6 months of treatment, the patient presented with localized patch of hair loss. Beginning of alopecia areata (AA) in patients with acne vulgaris could be regarded as a side effect of retinoids due to anti-acne therapy. The exact mechanism by which retinoids cause hair loss is not known.

Gupta M, Lotti T, Goldust M. Alopecia areata Due to Isotretinoin Treatment [published online ahead of print, 2020 Feb 21]. Dermatol Ther. 2020;e13280. Error - Cookies Turned Off
 
[OA] Formononetin: Novel Deal for Androgenetic Alopecia

To the Editor

Androgenic alopecia is a common genetic condition that can affect both men and women. Men with this case, can begin suffering hair baldness overtime as early as their teens through gradually decrease the size of hair follicles. Food and Drug Administration (FDA) and the European Medicines Agency (EMA) were approved the only topical minoxidil and oral finasteride as treatment for androgenetic alopecia.

Finasteride is made to prohibit the conversion of testosterone to Dihydrotestosterone (DHT) through inhibition of the testosterone 5α-reductase enzyme. The DHT has been linked to hormonal hair loss in men and women. The main side effect of oral finasteride is sexual effects (3.4-15.8%) including erectile dysfunction and decreased libido and ejaculate of men (1). A recent systematic review showed preliminary results on the safety and promising application of topical finasteride for alopecia therapy.

Indeed, finasteride displayed significant decrease of scalp and plasma DHT without any changes in serum testosterone (2). Furthermore, the administration of finasteride 0.25% solution/once daily at the doses of 100 and 200 μL exhibited an appropriate abrogation of scalp DHT potentially minimizing the undesirable sexual side-effects related to a systemic DHT reduction (3).

Here, we would like to shed light on novel candidate as alternative therapy for finasteride. Formononetin is a naturally occurring O-methylated isoflavone that obtained from red clover (Rimostil). It is a polyphenolic non-steroidal compound with estrogen-like biological activity. In the last decade several evidence demonstrated that formononetin has antimicrobial, antiviral (4), antioxidant, antilipidemic (5), antidiabetic (6), neuroprotective (7) and anticancer activity (8).

In 2016, pioneer work by Kim et al, concluded that the topical treatment of formononetin has hair regrowth effect through cell death surface receptor Fas/Fas ligand (Fas/Fas L)-induced caspase activation. In this study, authors demonstrated that formononetin was upregulated the anti-apoptotic Bcl-2 and downregulated the pro-apoptotic Bax and p53 (9). Recently, formononetin is well known to target p53 in numerous models.

Practically, several studies deduced that the local pharmacological abrogation of p53 useful to halt chemotherapy-induced hair loss. Moreover, p53-deficient mice showed neither hair loss nor apoptosis in the hair follicles keratinocytes after chemotherapy treatment (10).

Importantly, mounting evidence from experimental studies confirmed the inhibitory effect of formononetin on testosterone 5α-reductase enzyme (11). Hence, we suggest that the topical administration of formononetin may represent important drug candidate for use against androgenetic alopecia for men and women.

Consequently, further studies are required to confirm the novel mechanistic pathway of formononetin for androgenetic alopecia treatment. In addition, to elucidate the complete picture of topical administration of formononetin several outstanding questions should be answered linked to its concentration, delivery, administration frequency and side effects.

El-Arabey AA, Abdalla M. Formononetin: Novel Deal for Androgenetic Alopecia [published online ahead of print, 2020 Feb 18]. Arch Med Res. 2020;51(1):30–31. https://www.sciencedirect.com/science/article/pii/S0188440919310021?via%3Dihub
 
Hello everyone
Last year I noticed my hair thinning and some shinny spots on top and figured I was loosing it with age and started using Minoxidil. After 4-5 months I noticed big dark circles under my eyes and that I was looking old. I spoke to my Dr and was told that in rare case's that minoxidil can cause premature skin aging and have seen cases on the internet. After discontinuing I started collegen, biotin, iron and selenium and things are back to about 75% normal after stopping 5 months ago.
Just something for you using minoxidil to look out for.
 
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