VenomYo
Banned
Awesome
MESO-Rx
Anabolic Steroids
HCG degradation testing after 30, 45, 60 days
- Thread starter Liska
- Start date
Wasn’t there a recent test with Pregnyl testing pretty good? Or was that IBSA?
Liska
Subscriber
Haven't seen that, link please if you can find it!
janoshik
Subscriber
Semaglutide we already know for 2 weeks UNrefrigerated. Client permitted sharing the result, so I'll make a thread in a little while.Unfounded for TB500. Semaglutide we will know in a while
Sterkekoffie1
Member
It has always been kept refrigerated and only mixed in the week I will be using the vials .. it seems to me that if it is not mixed and it is stored at the right temperature it will not affect the function ... I kept getting my hcg and hmg from the hospital every six months ... they would not do this if the effect was less, it seems to me .. my VCM results also indicated a progression as the trajectory lasted longer .. so if I talk about your point degradation understand well this only applies to hcg that is already mixed .. correct me if i'm wrong
Stronglift
Member
Fair enough, looking forward to hearing more about the rest of the process. I guess it’s probably better to have a small fridge that keeps constant temperature and that you don’t open several times a day.
Liska
Subscriber
Everything in this thread is indeed about mixed/reconstituted HCG, not lyophilized in powder form still.
Sterkekoffie1
Member
Clear thanks
Liska
Subscriber
Day 45 post reconstitution update!
I will post the updated test report at the very end because I want the focus to be on this graph and its meaning, which makes the day 45 number irrelevant.
Black: day 0, Pink: day 31, Blue: day 45
While it doesn't look that much worse on paper, at this level of degradation there's a 50% margin of error and the testing method required to reduce that would take 'a shitload' of money & time. There's no point testing it after 60 days anymore because here's the takeaway:
Don't use generic HCG for longer than a month after reconstitution even when storing in the fridge at 2-8 degrees celsius. It will have degraded to the point where dosing it accurately is no longer possible, nor should you inject something with this level of degradation.
I'll perform this test again with pharmaceutical HCG once a correctly dosed product is available to the majority of the community, meanwhile I'll try whether additional stabilizers can remedy the degradation. I've added a disclaimer to my product page for harm reduction purposes right away.
I will post the updated test report at the very end because I want the focus to be on this graph and its meaning, which makes the day 45 number irrelevant.
Black: day 0, Pink: day 31, Blue: day 45
While it doesn't look that much worse on paper, at this level of degradation there's a 50% margin of error and the testing method required to reduce that would take 'a shitload' of money & time. There's no point testing it after 60 days anymore because here's the takeaway:
Don't use generic HCG for longer than a month after reconstitution even when storing in the fridge at 2-8 degrees celsius. It will have degraded to the point where dosing it accurately is no longer possible, nor should you inject something with this level of degradation.
I'll perform this test again with pharmaceutical HCG once a correctly dosed product is available to the majority of the community, meanwhile I'll try whether additional stabilizers can remedy the degradation. I've added a disclaimer to my product page for harm reduction purposes right away.
Stronglift
Member
This level of transparency is what this community needs for harm reduction. Thank you for the testing and for being open about your findings.
I freeze HCG inside slin pins and pull them out of freezer as needed. I’ve been under the impression that if frozen after reconstitution it will last significantly longer. Any idea how freezing affects longevity and potency?
HB_22
Well-known Member
Yes, freezing will destroy the Peptide in a reconstituted state.
First post, lurker here.
I think it's important you specify what concentrations you are reconstituting to as well as what solvents are you using (water for injections, sodium chloride 0.9%, bacteriostatic water) so as to eliminate the possibility that this may affect the results.
Higher concentration solutions (0.1ml/250IU) should degrade less quickly than Lower concentrations (0.1ml/100IU).
Peptides are also usually recommended to be reconstituted in either bacteriostatic water or water for injections (not sodium chloride 0.9%).
Sodium chloride is not recommended for peptide reconstitution due to its tendency to cause precipitates with acetate salts, afaik it may be used for immediate injection after reconstitution but not storage as it theoretically should degrade the peptide faster.
I think it's important you specify what concentrations you are reconstituting to as well as what solvents are you using (water for injections, sodium chloride 0.9%, bacteriostatic water) so as to eliminate the possibility that this may affect the results.
Higher concentration solutions (0.1ml/250IU) should degrade less quickly than Lower concentrations (0.1ml/100IU).
Peptides are also usually recommended to be reconstituted in either bacteriostatic water or water for injections (not sodium chloride 0.9%).
Sodium chloride is not recommended for peptide reconstitution due to its tendency to cause precipitates with acetate salts, afaik it may be used for immediate injection after reconstitution but not storage as it theoretically should degrade the peptide faster.
janoshik
Subscriber
We use 2 ml of HPLC grade water, so pretty much nothing written in the post applies.
Stronglift
Member
This is already for HCG. No need to do with HGH as most use doses where a single vial doesn’t last too long.
That’s impossible good sir. Because those frozen HCG syringes will bring my balls back from the dead In no time. So it definitely doesn’t destroy it.
janoshik
Subscriber
Pictures. For science.
cyclist5000
New Member
Was this tested on your/ or different HCG? Or Pregnyl? I am wondering why the Jano results show only around 7,000iu if the Pregnyl are supposed to have 10,000iu?
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