DugPrime
New Member
Like I said earlier, it’s up to you—if you prefer a 2-3 hour spike instead of a consistent high level that lasts 24 hours, that’s your choice. But just know, you can still use HGH alongside MK-677.At first, I’d want to compare the total increase in GH/IGF-1 over 24 hrs by calculating the area under the respective curves then pick the one which produces more total GH/IGF-1
On the other hand, the body produces spikes naturally so in theory it would make sense to use something which replicates natural spikes, albeit larger spikes.
Also, supposedly MK677 has a higher potential to reduce insulin sensitivity than synthetic HGH does.
Yeah, MK-677 induces insulin resistance, but who cares? You’d be surprised how easily you can mitigate that with a GLP-1 agonist or metformin. MK-677 is super cheap and isn’t harsh on the body. It’s not meant for long-term use, but running 10-25 mg for 3-4 months during a bulk, especially with insulin, is totally worth it.