HGH sleep issues

[400degrees]

About a month in on ugl GH, 4iu every night before bed, 2hrs after dinner. First couple weeks it knocked me out all night. Past couple weeks I've been wide awake at 3am every night. Almost feels like a cortisol spike. Wondering if I should ride it out, switch to am, or if anyone has had the same experience or knows the possible science behind this regarding the gh interactions with prolactin, progesterone or adrenals.

 

[iris]

that 1.5 IU GH daily is the mean (average) secretion for a normal BMI, height, 75 kg (165 lb) adult male in his twenties (22 - 28 years).

 

[Benf15harp]

Do you have refs for any of this? GH production per day by age bracket.

Don’t be lazy. Look it up

 

[songsofpyramids]

Don’t be lazy. Look it up

So, no, you don’t have the info. Thanks for sharing such useful information as always…

 

[Benf15harp]

So, no, you don’t have the info. Thanks for sharing such useful information as always…

 

[Liter O' Test]

sleep apnea? water retention?

 

[Ateam2023]

I don't understand how people get such harsh side effects from hgh , if water intake, diet, and cardio are in place people would have less severe sides imho , from experience when I wasn't on point with those three factors of course i had edema aggravated cts etc i think people take hgh in hopes of something profound to happen overnight which isn't the case at all

 

[Benf15harp]

I don't understand how people get such harsh side effects from hgh , if water intake, diet, and cardio are in place people would have less severe sides imho , from experience when I wasn't on point with those three factors of course i had edema aggravated cts etc i think people take hgh in hopes of something profound to happen overnight which isn't the case at all

This is an interesting take. As someone that stays dialed in 365. I cannot handle over 2.5ius of any HGH(including multiple UGL and pharmacy). I’ve tried every possible combination of timing and splitting doses to no avail. There’s definitely more to it.

 

[ksm2]

I also don't have any sleep inducing effect from it. Tried different doses, doesn't change anything. But when i sleep, the sleep is much better for sure.

 

[Ateam2023]

This is an interesting take. As someone that stays dialed in 365. I cannot handle over 2.5ius of any HGH(including multiple UGL and pharmacy). I’ve tried every possible combination of timing and splitting doses to no avail.

Then maybe hgh isn't for you , some people can't deal with hgh , there's plenty of other peds to use

 

[iris]

I also don't have any sleep inducing effect from it. Tried different doses, doesn't change anything. But when i sleep, the sleep is much better for sure.

Do you take it am/pm or just once, like OP?
I see most people do split the dose.

 

[ksm2]

Do you take it am/pm or just once, like OP?
I see most people do split the dose.

Only pm, like 8 pm. Never tried to split the dose, i've heard it's nonsense. Had pretty bad lethargy in the beginning, but i'm good now at 3.3 iu.

 

[iris]

Only pm, like 8 pm. Never tried to split the dose, i've heard it's nonsense. Had pretty bad lethargy in the beginning, but i'm good now at 3.3 iu.

Thanks.

BTW, your reply here

Listen to the haters and don't waste your time.

deserves to be turned into a t-shirt.
I gave you thumbs up for it because i love it.
I wanted to give you the love emoji but the combination of me + love + primo sounds a bit too weird...

So now you now.
Lol

 

[Benf15harp]

Then maybe hgh isn't for you , some people can't deal with hgh , there's plenty of other peds to use

Why? My levels are perfect on 2-2.5ius.

 

[Ateam2023]

Why? My levels are perfect on 2-2.5ius.

Then carry on

 

[Benf15harp]

Dosing should be split as you naturally produce 3+ pulses per day. 50-70% during sleep and the rest is distributed during the day. Ideally, 2 doses split 12 hours apart ie 11pm and 11am. So, if taking 4ius take 2.5-3 at night and the rest at daytime pin. Half life is 3 hours which means it’s completely eliminated after 18hours but 85% of that dose is gone in 9 hours. If doing one pin you’re pretty much at near zero for 15 hours and imo that’s suboptimal. But, do I as you wish.

 

[Type-IIx]

About a month in on ugl GH, 4iu every night before bed, 2hrs after dinner. First couple weeks it knocked me out all night. Past couple weeks I've been wide awake at 3am every night. Almost feels like a cortisol spike. Wondering if I should ride it out, switch to am, or if anyone has had the same experience or knows the possible science behind this regarding the gh interactions with prolactin, progesterone or adrenals.

The effect of GH on nighttime awakenings (currently) and lethargy (initially) has, in the former case, to do with direct GH effects on stage 3/4 sleep; and in the latter one, with effects on 11β-HSD1, decreasing it (thereby ↓conversion of inactive cortisone ⇒ active cortisol).

 

[songsofpyramids]

Never tried to split the dose, i've heard it's nonsense

I would try splitting dose am and pm and see if that helps the sleep issues. IMO split dosing feels the best and produces the best benefits for me personally. It also absolutely helped with my insomnia from hgh.

 

[ksm2]

I would try splitting dose am and pm and see if that helps the sleep issues. IMO split dosing feels the best and produces the best benefits for me personally. It also absolutely helped with my insomnia from hgh.

I will give it a try.

 

[Jin23]

The effect of GH on nighttime awakenings (currently) and lethargy (initially) has, in the former case, to do with direct GH effects on stage 3/4 sleep; and in the latter one, with effects on 11β-HSD1, decreasing it (thereby ↓conversion of inactive cortisone ⇒ active cortisol).

Yes, exactly as I've alluded too previously in this thread. I gotta start using me these \ | ≠ < ↑→, to get more likes! : D

We also forgot to mention the ↑fT3 due to rhGH ↓TBG which = ↑↑metabolic activity (increased BMR, cardiac output, etc.) alongside with heightened mood (due to ↑neurotransmitters, most notably increased excitatory neurotransmission) which feels particularly adrenergic, presumably due to T3's effects on increasing the expression of beta receptors, or in other words ↑β1/β2 expression, to be more clear.

 

[IronHouse]

I've always thought that it is one of its main good things that HGH promotes. Aparently it still comes down to an individual aspects. Same as everything else, you have to find your own way to adjust it