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Anabolic Steroids

how to make transdermal testosterone?

Yea. I read several opinions here from you, who use aoenas dmso! they liked to know if it will dissolve without heating
 
@Goingstronger

This is the quote from the phlojel guy:

IMHO you will get a much higher delivery rate without all the alcohol. I agree, PJU is a bit of a bitch to compound. The traditional squirt bottle transdermals are much easier. Just add powder and shake. However, I believe if you give it a try you will find even better results with the batch being thicker.

My favorite TD batch is 150mg 4AD/ 50mg 4OHT per ml. You will need a 60ml syringe. Take 9g of 4AD and 3g of 4OHT in a concave bowl or mortar. Add 3 to 5 ml of ethyl and levigate with a pestal or spatula and be sure to break down the 4OHT as the 4AD will blend easily into the ethyl. Once you have a paste weigh out the balance of PJU to make up the 60ml. So if you used 4ml of ethyl and you have a total of 12g of powder, you will need 44ml of PJU. PJU is almost 1:1 ratio of volume to weight. 1ml of PJU weighs 1.01g, so weight out 43.5g of PJU and add it to your paste in equal portions. Blend well and thoroughly. Once completed, open a new 60ml syringe, pull the plunger out and load the batch into the back with a spatula. Let it sit overnight.

When you add more than 10% alcohol in an effort to make it more towards a liquid you are reducing the lecithins ability to suround the drug. The way a lecithin based organogel works is the lecithin encapsulates the drug in a circle of molecules. It disrupts the cells of the stratum korneum and carries the drug in along with itself sort of like a trojan horse. I realize it's a pain in the ass to compound, but I promise you get better results. Also, as Strateg0s has pointed out, shower, scrub the area and shave any hair. I also like to take a little niacin right before I go to train in an effort to get more of the drug into my system. The niacin flush open small blood pathways that scavange the drug deposited right beneath the skin by the transdermal. I call it my transdermal turbo charge.

I mix a batch of some type of TD very regularly. I can bang out a batch of TD starting with a raw powder in about 15 minutes real time. Once you have it down, its very quick. Having the right tools helps.
 
baxter0312 said:
@Goingstronger

This is the quote from the phlojel guy:

IMHO you will get a much higher delivery rate without all the alcohol. I agree, PJU is a bit of a bitch to compound. The traditional squirt bottle transdermals are much easier. Just add powder and shake. However, I believe if you give it a try you will find even better results with the batch being thicker.

My favorite TD batch is 150mg 4AD/ 50mg 4OHT per ml. You will need a 60ml syringe. Take 9g of 4AD and 3g of 4OHT in a concave bowl or mortar. Add 3 to 5 ml of ethyl and levigate with a pestal or spatula and be sure to break down the 4OHT as the 4AD will blend easily into the ethyl. Once you have a paste weigh out the balance of PJU to make up the 60ml. So if you used 4ml of ethyl and you have a total of 12g of powder, you will need 44ml of PJU. PJU is almost 1:1 ratio of volume to weight. 1ml of PJU weighs 1.01g, so weight out 43.5g of PJU and add it to your paste in equal portions. Blend well and thoroughly. Once completed, open a new 60ml syringe, pull the plunger out and load the batch into the back with a spatula. Let it sit overnight.

When you add more than 10% alcohol in an effort to make it more towards a liquid you are reducing the lecithins ability to suround the drug. The way a lecithin based organogel works is the lecithin encapsulates the drug in a circle of molecules. It disrupts the cells of the stratum korneum and carries the drug in along with itself sort of like a trojan horse. I realize it's a pain in the ass to compound, but I promise you get better results. Also, as Strateg0s has pointed out, shower, scrub the area and shave any hair. I also like to take a little niacin right before I go to train in an effort to get more of the drug into my system. The niacin flush open small blood pathways that scavange the drug deposited right beneath the skin by the transdermal. I call it my transdermal turbo charge.

I mix a batch of some type of TD very regularly. I can bang out a batch of TD starting with a raw powder in about 15 minutes real time. Once you have it down, its very quick. Having the right tools helps.
Click to expand...

Yes so you still need to use a solvent at the beginning, no matter what.
I think you need to let the solvent + powder mix sit overnight before incorporating the cream/phlojel. Otherwise you still have grits when compounding.

I found an amazing compounding cream on Amazon that I'm going to try out.
It's an organogel based on lecithins, just like phlojel, for a fraction of the price:

Vanicream moisturizing skin cream jar with regular cap - 1 lb​

 
Goingstronger said:
Yes so you still need to use a solvent at the beginning, no matter what.
I think you need to let the solvent + powder mix sit overnight before incorporating the cream/phlojel. Otherwise you still have grits when compounding.

I found an amazing compounding cream on Amazon that I'm going to try out.
It's an organogel based on lecithins, just like phlojel, for a fraction of the price:

Vanicream moisturizing skin cream jar with regular cap - 1 lb​

Click to expand...

So vanicream has a transdermal action itself? I've looked at other creams and they all only sell to pharmacists.

And good point about letting it sit. If you let the alcohol evaporate it will get messy though
 
polarbear said:
If you get DMSO make sure to get it in glass bottles.
Click to expand...

No that's irrelevant for DMSO, Jensen stores them in a type of plastic that doesn't leach.

The only relevant point for DMSO is to get a purity higher than 99.99% and sterile-filtered.

The only company that combines these two pre-requesites is Jensen, and stores the DMSO in a plastic that doesn't leach.
You shouldn't get DMSO from anyone else unless you plan on smelling like oyster and absorbing toxins.
 
baxter0312 said:
So vanicream has a transdermal action itself? I've looked at other creams and they all only sell to pharmacists.

And good point about letting it sit. If you let the alcohol evaporate it will get messy though
Click to expand...

Yes it has a transdermal action of itself.
 
Goingstronger said:
Why would you bother with glass and spatula?

I use a portable milk frother to mix the cream, the alcohol and the powder. It's very efficient at mixing everything.
Click to expand...

Because that's what a compound pharmacy would do for a made to order cream, it's how you get the grits out. For huge batches there's a special machine they have, but it's not a milk frother. I think you are using way too much alcohol to dissolve the powder so you don't have any grit to worry about in the first place.
 
Goingstronger said:
So now the DMSO is shooting the PEG400 right into his bloodstream at an unknown rate.
I wouldn't do that if you are concerned about health.
Click to expand...
Time for the second attenpt.
Was thinking about 50% dmso, some isopropyl alcohol and peg-400. will lower the peg this time for health concerns
 
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baxter0312 said:
Just got my DHT blood results back. I applied cream 3 hours before the test.

Dihydrotestosterone 265 High ng/dL
Reference Range:
Adult Male: 30 - 85

Previous test was 32 ng/dL
Click to expand...
With what cream base?
At what test concentration?
 
baxter0312 said:
Phlojel, no dmso. 10% dht

To be honest i have given up on the experiment for now, the DHT wasn't giving me any benefits and too much was going systemic.
Click to expand...
I'm trying DHT in DMSO from times to times, it's very underwhelming.
It's mostly calming and focus-giving at the same time, but that's it.
Testosterone in DMSO has so much more "feelz" to it: libido, anabolism, energy.
 
I am also interested in taking testosterone in dmso for TRT because i find it extremely simple and easy to integrate in a daily routine

The problem with testosterone base in dmso is it hits you very hard and very fast but the effects do not last long. So you need to apply it 2-3 times per day. This method also has a major problem: it loses some power over time, likely because of repeating extreme stimulation of the dopamine system caused by sudden and brief sky high testosterone levels. This probably cause some dopamine desensitization over time.

remember guys, men only produces a total of around 3-9mg of test through an entire day.

with testosterone in dmso, it's dozens of mg absorbed in a matter of minutes ! I dont think it's very natural. Testosterone TNE and suspension are also pure testosterone but the absorption is slower because of the oil and crystals. With dmso its straight to the blood in minutes.

we are interested in trying testosterone acetate in dmso for a steady level of test through the day. It seems acetate ester is soluble in dmso, a lot of guys used trenbolone acetate from implant pellets (Finaplix) in dmso back in the days. I just hope the ester can pass the skin because it will be live changing for TRT
 
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