how to make transdermal testosterone?

[sinewave3]

Does anyone know what happens if you put nandrolone base in DMSO?

I assume it would absorb, but would there be any issue with conversion to something else?

If you have nan base should be good! Just like tren base or test base. If you try it post up how you like it.

 

[Deleted member 59947]

Yeah thanks man, pretty cool idea

I did 50mg/ml, and I apply 0.5ml twice a day = 350mg test a week

If I had to do it again, and after this one runs out, I'm going to make it more concentrated with less dmso for less of a hassle. What concentration did you do?

I make 75mg/ml and I apply a full droper twice a day

 

[Deleted member 59947]

Does anyone know what happens if you put nandrolone base in DMSO?

I assume it would absorb, but would there be any issue with conversion to something else?

Yes it will absorb just fine.
As long as there is no ester attached, everything mixes very well in DMSO

 

[kdq99]

Yes it will absorb just fine.
As long as there is no ester attached, everything mixes very well in DMSO

Is there anywhere in particular you would reccomend getting these ingredients?

 

[ripriot]

10%? A good cream compounded with Pentravan and a solvent is more like 30%.
Pure DMSO has 100% absorption, so the 50mg testosterone in DMSO I'm applying fully make it to my bloodstream

The skin is not a sponge. You do not get 100% of base product to perentrate the dermal layer with DMSO.

DMSO easily penetrates the skin (176 ± 42 g/m2/hr) compared to, for example, water (14.8 ± 0.1 g/m2/hr), but because of DMSO’s low toxicity (see previous section) and the fact that this same permeability test showed DMSO does not carry less-permeable substances with it through the skin, it can be concluded that DMSO does not pose a significant threat by skin absorption. The penetration rate of DMSO in solutions is a direct function of the mole fraction of DMSO. (Ursin, et. al. 1995)14. Although DMSO readily penetrates human skin in concentrations of 70-100%, at concentrations of 67% or less, DMSO molecules are hydrated, which greatly reduces dermal penetration (Sulzberger et. al., 1966; Brayton, 1986: Woodford and Barry, 1986).

 

[FlyGuy3232]

The skin is not a sponge. You do not get 100% of base product to perentrate the dermal layer with DMSO.

DMSO easily penetrates the skin (176 ± 42 g/m2/hr) compared to, for example, water (14.8 ± 0.1 g/m2/hr), but because of DMSO’s low toxicity (see previous section) and the fact that this same permeability test showed DMSO does not carry less-permeable substances with it through the skin, it can be concluded that DMSO does not pose a significant threat by skin absorption. The penetration rate of DMSO in solutions is a direct function of the mole fraction of DMSO. (Ursin, et. al. 1995)14. Although DMSO readily penetrates human skin in concentrations of 70-100%, at concentrations of 67% or less, DMSO molecules are hydrated, which greatly reduces dermal penetration (Sulzberger et. al., 1966; Brayton, 1986: Woodford and Barry, 1986).

Do you have evidence regarding how much penetration to expect with a base substance and pure DMSO?

 

[ripriot]

Do you have evidence regarding how much penetration to expect with a base substance and pure DMSO?

I don’t get into transdermals. Penetration will depend on % of solvent used (DMSO). 10%, 15%, 20%. Higher % the higher probability a skin reaction can occur. It will depend on the base compound your using. It will depend on the part of body applied to. I just know that that it’s not 100%. Look up Jay Campbell. He is an advocate for transdermal creams. He says highest absorption rate is the back of your nut sack.

 

[Dthcore]

4 times the top range when my T is twice the top range

Would using this eliminate something like Finasterides DHT inhibition since it’s such a fast acting test? Seems I’m allergic to about every carrier oil out there. Thinking about making transdermal. Last resort

 

[Dthcore]

Yeah but he followed that up immediately with how high the concentration can be.

Anyways, this thread is kind of fucked... But I made a batch this week and have to say, was pretty impressive compared to test base injectable. 100mg per ml of DMSO gel works great. Really hit hard... I don't know if I'll bother with the hassle of injectable test base anymore, this is easier by far and works faster.

HOLY SHIIIIIIIIT!! 100mg per ml!? It didnt crash on you?

 

[Dthcore]

I make 75mg/ml and I apply a full droper twice a day

DAMN!!! Thats a little over a gram a week! Holy fuck this shit is amazing! xD

 

[sinewave3]

HOLY SHIIIIIIIIT!! 100mg per ml!? It didnt crash on you?

That’s a common concentration for pro hormones. I have same holding in the commercial carrier called Salvo no crashes.

 

[KingCahoot3627]

That’s a common concentration for pro hormones. I have same holding in the commercial carrier called Salvo no crashes.

Me too. I am dabbling with some 6oxo in the Salvo carrier and its working great. I can't imagine more than 3g of anything in 1 bottle of Salvo though.

 

[sinewave3]

Me too. I am dabbling with some 6oxo in the Salvo carrier and its working great. I can't imagine more than 3g of anything in 1 bottle of Salvo though.

Salvo with some added DMSO is where it’s at! Try that yet?

I agree that putting 3g of powder in a single 30 ml bottle is tough, got to take some out and put it in another bottle when adding the powder, then fill it back up once it’s all dissolved.

 

[KingCahoot3627]

Salvo with some added DMSO is where it’s at! Try that yet?

I agree that putting 3g of powder in a single 30 ml bottle is tough, got to take some out and put it in another bottle when adding the powder, then fill it back up once it’s all dissolved.

Not yet. But after reading this thread again a second time, I think I'm going to add some DMSO.

Does the DMSO help with absorption? Or does it help keep our concoctions stay in solution?

How much would u add to Salvo?

 

[ripriot]

Not yet. But after reading this thread again a second time, I think I'm going to add some DMSO.

Does the DMSO help with absorption? Or does it help keep our concoctions stay in solution?

How much would u add to Salvo?

DMSO is a penetration enhancer and solvent. It's used in conjuction with other chemicals to enhance penetration of the dermal layer.

I don't know what salvo is...

 

[ripriot]

Not yet. But after reading this thread again a second time, I think I'm going to add some DMSO.

Does the DMSO help with absorption? Or does it help keep our concoctions stay in solution?

How much would u add to Salvo?

This might help answer some of your questions...

Frequent Q&A

 

[sinewave3]

Not yet. But after reading this thread again a second time, I think I'm going to add some DMSO.

Does the DMSO help with absorption? Or does it help keep our concoctions stay in solution?

How much would u add to Salvo?

The DMSO helps penetrate the skin.

If your skin is sensitive start with 10% DMSO so roughly 3ml or droppers in a full bottle (or after you take some out). Personally I like double that, and if any skin gets irritated I will lay off that site for a couple days. Seems to help absorption.

Have also read that pre treating a site with DMSO, then applying the hormone solution to that spot works too, but I like the 1 step approach.

 

[KingCahoot3627]

The DMSO helps penetrate the skin.

If your skin is sensitive start with 10% DMSO so roughly 3ml or droppers in a full bottle (or after you take some out). Personally I like double that, and if any skin gets irritated I will lay off that site for a couple days. Seems to help absorption.

Have also read that pre treating a site with DMSO, then applying the hormone solution to that spot works too, but I like the 1 step approach.

Great info! 3ml sounds like a good starting point. Unfortunately, I had to stop the 6oxo. Im pretty sure I crashed estrogen. I used to be able enjoy trione however I wanted but I guess I'm getting old now and have follow the common sense shared on boards like meso.

 

[ripriot]

Once again being a condescending dick. Have you read the rest of this forum?? Have you seen how many fucking recipes people give? Do you know what a recipe is? Are you scared to give a recipe because you have a misguided view of legal liability? what if I don't want apply 1ml what if I only want to apply .3ml. do you know what the maximum amount of powder that will hold in solution?

He doesn't know shit. Thinks you just put some base with DMSO and you get 100% absorption rate. He doesn't love the details!

 

[ripriot]

Of course not. But he seems confused on how to go from 50/1 ml to 50/.3 ml. That's basic math.

Lets see you expain it in detail please?