Human Growth Hormone - QSC vs Meditrope Golden Tops. What the fuck?

[LSDPowerlifting]

no
theres a reason why serostim is for HIV patients, treating burns... and saizen is for growth issues

I disagree, it's more likely pharma-company payoffs and medical-politics causing regulations to have the standard set for their HGH only, like Serostim for AIDS. Generics work nearly just as good, there's no reason to pay 5 to 10 times the price for pharma, unless you have money to burn. I didn't find them to produce any better results, just a tiny bit less water-retention, and it really was just a tiny bit less.

 

[xeonmasters]

Somatrope is somatrope… no diffrence … all 191 Amino acids .
you are posting theses here that have no support and no evidence. if I have both HGH laboratory tested, comes on end the same result and so it is in the body. this only recognizes the 191a and processes it

is chemically synthetized somatropin is the same as recombinant dna somatropin (e.coli, mammalian cells)? it has the same biological activity on the human body? same as insulin, chemically synthetized insulin has no biological activity

Table 8, Description of Somatropin Products - Somatropin (Genotropin) for Subcutaneous Injection - NCBI Bookshelf

and I highly suggest you to take a look on pharmacology books. in the laboratory HGH is HGH, but at human body IS NOT

 

[xeonmasters]

I disagree, it's more likely pharma-company payoffs and medical-politics causing regulations to have the standard set for their HGH only, like Serostim for AIDS. Generics work nearly just as good, there's no reason to pay 5 to 10 times the price for pharma, unless you have money to burn. I didn't find them to produce any better results, just a tiny bit less water-retention, and it really was just a tiny bit less.

yes. some generics are very good, and in my opinion "only pharma hgh is good" is bullshit

but about medical-politics standarding, i will disagree. serostim stalls on igf/gh levels, while saizen does not (for example)

 

[LSDPowerlifting]

is chemically synthetized somatropin is the same as recombinant dna somatropin

I thought it all had to be grown. What would be the difference anyway?

serostim stalls on igf/gh levels, while saizen does not (for example)

According to who?

 

[xeonmasters]

I thought it all had to be grown. What would be the difference anyway?



According to who?

1) peptides like bpc-157, tb500 are chemically synthetized, for example. those peptides will work anyway. but, synthetic insulin/somatropin will produce antibodies, and wont bind correctly to the body. it needs to be grown from e.coli/yeast/mammalian cells (like Saizen) to look like "natural".

you have plenty of failed studies of chemically synthetized human insulin in 1950's

Insulin: A pacesetter for the shape of modern biomedical science and the Nobel Prize - PMC

The 100th anniversary of the discovery of insulin in Toronto in 1921 is an important moment in medical and scientific history. The demonstration that an extract of dog pancreas reproducibly lowered blood glucose, initially in diabetic dogs and then ...

www.ncbi.nlm.nih.gov

2)

There may be an association between GH antibodies (i.e., antigenicity) with mammalian cell-derived rhGH versus E. coli (e.g., Iranian Norditropin saw 8.5% antigenicity versus 1.2-2.8% for E. coli-produced Somatropin). Yet, there was no clinical relevance (no decrement in GH response [IGF-I increase] nor height velocity).

There may be some minor influence of excipients used (e.g., some rhGH formulations may use mannitol which is a diuretic) on body composition. Genotropin uses meta cresol primarily. Serono Serostim sucrose & phosphoric acid.

Anyway, with all rhGH formulations there is a "stalling" after some time (due to diminished GH response, likely due predominantly to GHBP/IGFBP dynamics, diminished phosphorylation of downstream elements to the GHR, etc.)

I think the perceived differences by formulation are largely modulated by time * dose and by nutritional and training influences, other drugs.

 

[Alibabaa]

Maybe @janoshik can say more … he Knows a lot about the chemical structure .

In my opinion there is no different between the HGH . Also for the Body ..

for everyone , hgh is hgh no matter what it is derived from . if it has 191 amino acids (and i don't know anything else), then it works the same.

 

[Alibabaa]

1) peptides like bpc-157, tb500 are chemically synthetized, for example. those peptides will work anyway. but, synthetic insulin/somatropin will produce antibodies, and wont bind correctly to the body. it needs to be grown from e.coli/yeast/mammalian cells (like Saizen) to look like "natural".

you have plenty of failed studies of chemically synthetized human insulin in 1950's

Insulin: A pacesetter for the shape of modern biomedical science and the Nobel Prize - PMC

The 100th anniversary of the discovery of insulin in Toronto in 1921 is an important moment in medical and scientific history. The demonstration that an extract of dog pancreas reproducibly lowered blood glucose, initially in diabetic dogs and then ...

www.ncbi.nlm.nih.gov

2)

don't you see what the person writes there? there is no clinical evidence of this. everything was the same GH in the body and IGf1 increase. Connections would be possible due to nutrition and training. HGH is HGH...

 

[janoshik]

In my opinion there is no different between the HGH . Also for the Body ..

I hold the same opinion

 

[xeonmasters]

Maybe @janoshik can say more … he Knows a lot about the chemical structure .

In my opinion there is no different between the HGH . Also for the Body ..

for everyone , hgh is hgh no matter what it is derived from . if it has 191 amino acids (and i don't know anything else), then it works the same.

okay
your opinion changed my mind
thats why Olympias PRO are using HGH Blue Tops right 100 usd/kit now

 

[Alibabaa]

okay
your opinion changed my mind
thats why Olympias PRO are using HGH Blue Tops right 100 usd/kit now

yes they do …believe me they do . and the Price is 50 USD/kit
Same
Quality like Pharma hgh

 

[LSDPowerlifting]

I've recently come under the belief that some pros are using several hundred iu's per day, which would make pharma out of the question unless you were a billionaire.

 

[janoshik]

1) peptides like bpc-157, tb500 are chemically synthetized, for example. those peptides will work anyway. but, synthetic insulin/somatropin will produce antibodies, and wont bind correctly to the body. it needs to be grown from e.coli/yeast/mammalian cells (like Saizen) to look like "natural".

'Chemical synthesis' of peptides gets more expensive with length of peptide. The reason for recombinant technology here are economical.

 

[Alibabaa]

I've recently come under the belief that some pros are using several hundred iu's per day, which would make pharma out of the question unless you were a billionaire.

Yes thats Right . More as 50 i.u per day . Only generic hgh is possible for this

 

[MrHowie]

no
theres a reason why serostim is for HIV patients, treating burns... and saizen is for growth issues

The reason is one got a patent and the other company didn’t. Dave goes over it briefly in this video…


View: https://www.youtube.com/live/ztdUEZ7GA9Q?feature=share

 

[MrHowie]

I've recently come under the belief that some pros are using several hundred iu's per day, which would make pharma out of the question unless you were a billionaire.

Then they are misinformed because there is actually a limit when it doesn’t really adds anymore IGF so you would only be getting possible other benefits oh HGH outside of increased IGF if any…

Reference


View: https://youtu.be/ssVp1pTH9ak

 

[Gigantic]

Stop derailing my thread with anti scientific garbage, Xeon.

 

[xeonmasters]

Stop derailing my thread with anti scientific garbage, Xeon.

sorry, bro. I know every HGH is equal now and Big Ramy is using QSC kits right now

 

[xeonmasters]

'Chemical synthesis' of peptides gets more expensive with length of peptide. The reason for recombinant technology here are economical.

i wish biosynthesis was basic. and not even HGH are prescribed equal here for kids, i just can imagine this for bodybuilders

but as alibabaa has told, every PRO is using blue tops. The China man killed Pfizer and Senoro at same time

rest my case here. god bless u all, iron friends

 

[LSDPowerlifting]

Then they are misinformed because there is actually a limit when it doesn’t really adds anymore IGF so you would only be getting possible other benefits oh HGH outside of increased IGF if any…

Reference


View: https://youtu.be/ssVp1pTH9ak

In my recent experience, the igf doesn't matter, in practice I'm seeing linear gains from hgh as the dose goes up

 

[AlexDavis43]

I hold the same opinion

Yeah, probably. But I could also see how modifications (eg, glycation, lipidation, oxidation, etc.) (maybe different for microbial vs mammalian sources) or additives could influence bioactivity, stability, etc.