Sorry if I've missed this in the thread but whats the difference between say Modaheal 200mg and Modavigil 200mg? Both say they are 200mg of modafinil but I believe Ive felt different on each and others in the thread seem to have said similar? I had a quick look online for ingredients but again just see 200mg modafinal?
@Ghoul any thoughts please?
The difference is in pharmacokinetics. How much, and how quickly the active ingredient is absorbed.
This is dependent on the formulation of the other non-active ingredients (excipients), and the physical manufacturing process of the tablet.
Let me preface this by saying I've never seen evidence of "bunk" Moda. The active ingredient is very cheap. About a penny per tablet. The "bunk" paranoia goes back to the days when it was closer to $5 per tablet. Every lab test I've seen shows around 200mg of Modafinil is present.
The primary difference between Moda tabs comes from whether or not, and how well, one step of the manufacturing process is performed.
The grinding and sifting of the active ingredient into relatively uniform, microscopic particles.
This is not like grinding and sifting flour, but a very complex process working at a level that can only be checked by electron microscope.
When the pharma manufacturer receives the active ingredient (which I believe is mostly made in Korea and Japan), the particles vary widely in size. Larger particles are not absorbed as quickly, or at all.
In this chart, you can see one sample of Moda absorbs quickly, hits maximum blood concentration early, and stays there. .
The other samples absorb more slowly, never reach the same peak, and drop off sooner.
So despite all being the same dosage, each of the tablet formulations are experienced differently by the user.
Sun is part of a multibillion dollar pharma conglomerate, and has access to the equipment and expertise to ensure consistency from batch to batch, regardless of how the active ingredient comes in. It's processed into a uniform size.
HAB is next best.
The rest of the manufacturers will produce different results based on how the raw material comes in. Some batches have lots of poorly absorbed large particles, others have. high proportion of small particles, so its luck of the draw and lots of variation from one tab to another.