Joints/Tendons/Bone

[Open Access] Davies JF, et al. Bilateral Patella Tendon Ruptures Associated With Anabolic Steroid Abuse. EC Orthopaedics 2015;2.1:43-6. https://www.ecronicon.com/ecor/orthopaedics-ECOR-02-00009.php

Bilateral patella tendon ruptures are rare and typically seen in patients with systemic disease or long term corticosteroid therapy.

There are no previous documented cases of bilateral patella tendon ruptures in association with anabolic steroid abuse.

Bilateral quadriceps ruptures associated with anabolic steroids have been previously reported in two cases.

A patient with bilateral, simultaneous mid-substance patella tendon ruptures who had been using anabolic steroids during a training regime for a competitive weight lifting event is presented with a discussion of the literature.
 
[Open Access] Davies JF, et al. Bilateral Patella Tendon Ruptures Associated With Anabolic Steroid Abuse. EC Orthopaedics 2015;2.1:43-6. https://www.ecronicon.com/ecor/orthopaedics-ECOR-02-00009.php

Bilateral patella tendon ruptures are rare and typically seen in patients with systemic disease or long term corticosteroid therapy.

There are no previous documented cases of bilateral patella tendon ruptures in association with anabolic steroid abuse.

Bilateral quadriceps ruptures associated with anabolic steroids have been previously reported in two cases.

A patient with bilateral, simultaneous mid-substance patella tendon ruptures who had been using anabolic steroids during a training regime for a competitive weight lifting event is presented with a discussion of the literature.

.....and these results should not be extrapolated to sheep :)
 
After reading all this i still feel we haven't got the bottom of whether AAS use can help heal ligament/tendon injuries. I recently severely injured my ankle whilst i was using NPP, Tren and test and am due for some surgery to put things back together. I feel that the injury was more of a freak injury rather than me being more prone to it because of AAS use but the thought still comes to my head about what if I wasn't using anything and had the same accident. Although I do not want to pressure my ligaments and tendons to much but I would like to prevent muscle wasting. Another issue is the fact that during this time i would like to give my body a rest from 19 nor steroids due to the fact that I just Don't see the point of putting up with all the side effects while I can not train at my full potential at the gym. Now while saying this I have access to legit primo and eq. Would it be worthwhile adding these things into the mix? or just some gh? I would like to know everyones thoughts. I am also thinking that instead of test I will do HCG 250iuX3 Weekly just to avoid further Collagen issues. Another issue I can think of is the kicking time for EQ any suggestions here as well? Help would be much appreciated. All bloods are in check so no issues there and I'm allowed to start doing upper body work in the gym the week after surgery.

Oh I think it relatively clear AAS do NOT selectively enhance collagen synthesis that is destined for articular or periarticular structures such as ligaments or tendons.

This becomes even more obvious when the remarkable influence AAS have on SKM is compared to their PALTRY effects on purely collagenous structures.
 
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Kanayama G, DeLuca J, Meehan WP, 3rd, Hudson JI, Isaacs S, et al. Ruptured Tendons in Anabolic-Androgenic Steroid Users: A Cross-Sectional Cohort Study. Am J Sports Med. http://ajs.sagepub.com/content/early/2015/09/11/0363546515602010.abstract

BACKGROUND: Accumulating case reports have described tendon rupture in men who use anabolic-androgenic steroids (AAS). However, no controlled study has assessed the history of tendon rupture in a large cohort of AAS users and comparison nonusers.

HYPOTHESIS: Men reporting long-term AAS abuse would report an elevated lifetime incidence of tendon rupture compared with non-AAS-using bodybuilders.

STUDY DESIGN: Cohort study; Level of evidence, 3.

METHODS: Medical histories were obtained from 142 experienced male bodybuilders aged 35 to 55 years recruited in the course of 2 studies. Of these men, 88 reported at least 2 years of cumulative lifetime AAS use, and 54 reported no history of AAS use. In men reporting a history of tendon rupture, the circumstances of the injury, prodromal symptoms, concomitant drug or alcohol use, and details of current and lifetime AAS use (if applicable) were recorded. Surgical records were obtained for most participants.

RESULTS: Nineteen (22%) of the AAS users, but only 3 (6%) of the nonusers, reported at least 1 lifetime tendon rupture. The hazard ratio for a first ruptured tendon in AAS users versus nonusers was 9.0 (95% CI, 2.5-32.3; P < .001). Several men reported 2 or more independent lifetime tendon ruptures. Interestingly, upper-body tendon ruptures occurred exclusively in the AAS group (15 [17%] AAS users vs 0 nonusers; risk difference, 0.17 [95% CI, 0.09-0.25]; P < .001 [hazard ratio not estimable]), whereas there was no significant difference between users and nonusers in risk for lower-body ruptures (6 [7%] AAS users, 3 [6%] nonusers; hazard ratio, 3.1 [95% CI, 0.7-13.8]; P = .13). Of 31 individual tendon ruptures assessed, only 6 (19%) occurred while weightlifting, with the majority occurring during other sports activities. Eight (26%) ruptures followed prodromal symptoms of nonspecific pain in the region. Virtually all ruptures were treated surgically, with complete or near-complete ultimate restoration of function.

CONCLUSION: AAS abusers, compared with otherwise similar bodybuilders, showed a markedly increased risk of tendon ruptures, particularly upper-body tendon rupture.
 
I suspect a major contributor to the higher frequency of upper vs lower extremity tendon disruptions is the much higher incidence of impingement syndrome in those patient under study (age 35-55).

Moreover lower extremity tendon tears (Quadriceps and Achilles) almost always involve a mobile rather than stationary mechanism, and is almost exclusively associated which rapid muscular contraction and relation.

This is not the case in upper exit tendon tears!

Since "aerobic" exercise is not the primary means thru which "muscles are built" a reduction of lower extremity tendon injuries is not surprising, IMO.

However considering how frequently the shoulders are either directly or indirectly involved in any Bb exercise routine higher freuebcy if upper extremity tendon tears should also be expected.
 
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Keener JD, Sethi PM. Distal Triceps Tendon Injuries. Hand Clin 2015;31(4):641-50. http://www.hand.theclinics.com/article/S0749-0712(15)00076-1/abstract

Acute triceps ruptures are an uncommon entity, occurring mainly in athletes, weight lifters (especially those taking anabolic steroids), and following elbow trauma. Accurate diagnosis is made clinically, although MRI may aid in confirmation and surgical planning. Acute ruptures are classified on an anatomic basis based on tear location and the degree of tendon involvement. Most complete tears are treated surgically in medically fit patients. Partial-thickness tears are managed according to the tear severity, functional demands, and response to conservative treatment. We favor an anatomic footprint repair of the triceps to provide optimal tendon to bone healing and, ultimately, functional outcome.
 
Why are tendon tears more common in AAS users?

In part because the drastic improvement of muscular strength that often accompanies AAS use, far exceeds the tensile capabilities of their tendonious attachments. The reason for the latter, as collagenous structures such as ligaments, tendons and cartilage possess a relatively avascular, they require considerably more time to equal the hypertrophic changes of SKM.

It's analogous to placing a 454 engine in a Volkswagen, the structural support is simply unable to tolerate the forces generated by the engine, and eventually something is "gonna give"!
 
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Need some help guys. I'm experiencing tendinitis in my right elbow. I strained it playing basketball which I haven't played in years. The week after I did back and bi workout. And man I was in pain for a couple days after that. It's been effecting me work. And have taken a full week off from the gym feels much better. But I can still feel it and if I train hard or move it wrong at work I feel it will be back again. Did back and biceps the other day back portion was fine. But couldn't do bb curls. Or hammer curls really felt it in the elbow. Was planing on starting a cycle in two weeks test deca dbol. Was thinking it be better to wait til it heals more so I don't hurt it pushing weight. Any ideas??
 
2009 Feb;129(2):281-6. doi: 10.1007/s00402-008-0603-0
High-dose vitamin C supplementation accelerates the Achilles tendon healing in healthy rats.
Omeroğlu S1, Peker T, Türközkan N, Omeroğlu H

High-dose vitamin C supplementation accelerates the Achilles tendon healing in healthy rats. - PubMed - NCBI



INTRODUCTION:
This experimental study was performed to assess, whether or not, vitamin C, required during the collagen synthesis, would influence the Achilles tendon healing in a healthy rat model.

MATERIALS AND METHODS:
The right Achilles tendons of 42 healthy female Wistar Albino rats were completely ruptured. The rats were randomly divided into the vitamin C and control groups and both groups included third, tenth and twenty-first day subgroups. One hundred and fifty milligrams (1.5 cc) of vitamin C and 1.5 cc % 0.9 NaCl were injected once for every 2 days for the vitamin C and control groups, respectively. Qualitative and quantitative microscopic comparisons of the repair tissues of both groups were made on the mentioned days.

RESULTS:
Angiogenesis was more evident on the third day in the vitamin C group. There was a significant difference between the control and vitamin C groups regarding the type I collagen production on the tenth day. The structure of the repair tissue was almost in the form of regular dense connective tissue at the end of twenty-first day in the vitamin C group. Mean collagen fiber diameter was considerably higher, and the number of active fibroblasts in the repair tissue was slightly elevated in the vitamin C group during the entire healing process.

CONCLUSION:
High-dose vitamin C supplementation once for every 2 days has stimulating effects on the Achilles tendon healing because of early angiogenesis and increased collagen synthesis in a healthy rat model. Further studies are needed to make clear the mentioned encouraging effects of the vitamin C on the Achilles tendon healing.
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Purely anecdotal, but I strongly feel that vitamin C (4g ED) had kept away any injuries when I was lifting twice the amounts I currently do, and recently has helped me recover from tendon aches in my hamstrings, triceps and biceps tendons. I realised I had stopped supplementing vitamin C for over a year, started again (2g ED) and felt improvement within a fortnight.
 
If I recall correctly Vitamin C also cured the common cold, shrunk the prostate, and exhibited aphrodisiac effects, etc, etc, etc and ALL were eventually proven BOGUS.
 
If I recall correctly Vitamin C also cured the common cold, shrunk the prostate, and exhibited aphrodisiac effects, etc, etc, etc and ALL were eventually proven BOGUS.
Its good for erections too, just sprinkle a little on your junk and then watch some porn. Works 50% of the time apparently.

I thought vitamin C was required for the body to form collagen?
 
Although i realise increased vitamin C intake doesnt necessarily mean increased collagen synthesis.
 
It is, and in fact a SEVERE deficiency of vitamin C can lead to scurvy. (Never seen ONE CASE) but the vitamin C is an enzymatic -cofactors and its absence weakens the collagen lattice.

But the primary components of collagen includes 3 amino acids Glycine, Lycine and ...? Should you eat only those three AA to promote collagen synthesis,not.

It follows exceeding the RDA to enhance the synthesis of naturally produced compounds just doesn't fly fella.

How about this fine example, since the PRECURSOR for TT is cholesterol, those with low TT need only to INCREASE the amount of cholesterol in their diet? NOT A GOOD IDEA, :)
 
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