Jin23
Well-known Member
Tradeoff. Neither 325 mg/day nor 81 mg/day seem to exacerbate symptoms but I'll get a better look inside soon.
So far I've weighted the potential cardiovascular benefit more heavily than any gut hit for my personal objective function.
Actual net negative for low dose aspirin with IBD is murky from my understanding. What are your thoughts?
Daily Aspirin Use Does Not Impact Clinical Outcomes in Patients With Inflammatory Bowel Disease
AbstractBackground. Although several studies have associated the use of nonsteroidal anti-inflammatory drugs with disease flares in patients with inflammatacademic.oup.com
The impact of aspirin use on outcomes in patients with inflammatory bowel disease: Insights from a national database - PMC
Inflammatory bowel disease (IBD) is an inflammatory disorder that can increase the risk of mortality. Aspirin is an anti-inflammatory drug used for primary prevention of cardiovascular events. A single center analysis previously reported that ...www.ncbi.nlm.nih.gov
Aspirin, Nonsteroidal Anti-inflammatory Drug Use, and Risk for Crohn Disease Ulcerative Colitis: A Cohort Study - PMC
Aspirin and nonsteroidal anti-inflammatory drugs (NSAIDs) are anti-inflammatory but have been linked in some studies to Crohn disease (CD) and ulcerative colitis (UC). To assess the association between aspirin and NSAID use and incident CD and UC. ...www.ncbi.nlm.nih.gov
International consensus on the prevention of venous and arterial thrombotic events in patients with inflammatory bowel disease - Nature Reviews Gastroenterology & Hepatology
Patients with inflammatory bowel disease (IBD) are at increased risk of thrombotic events. This Evidence-Based Guideline presents an international consensus on the prevention of venous and arterial thrombotic events in patients with IBD, and includes 19 recommendations for clinical practice.www.nature.com
Yes, I see. I haven't ever looked up aspirin and IBD. My reasoning was simply NSAIDs = bad gut health; GI bleeding, stomach ulcers, h. pylori, gi perforation, increased intestinal permability, etc. We all know NSAIDs have a poor reputation in regards to gut health. However the links you provided seem to point to some sort of a net neutral or possibly even a positive effect on IBD. I'll have to take a deeper look in to it, but I'm not that interested tbh, so that may or may not happen : )
The thought of causing gut microbleeds just sounds like blasphemy to me. GI health is sacred to me, as it should be to everybody.