Masteron, Nolvadex, Letrozole, Cabergoline, Anastrozole, Aromasin, ...

[caffeinatedlogic]

etc.

What is the most effecient and/or effective combination for controlling (not crushing) E2 and avoiding gyno? Say if you had to pick just one or two.

 

[bighunanballs]

As much test as you can handle side effect free without an AI then load up the masteron. For me I'm at 500 test, 500 mast.

 

[xrayphoton13]

Well masteron can help prevent gyno but it won't control your e2. I would pick aromasin for that. Anastrozole is known for weakening bones and causing fractures whereas aromasin is bone anabolic. Nolvadex has its uses but raloxifene would be the better choice for avoiding gyno as it's more site specific to the breast. I haven't used letro or caber. I see no reason to use them with the way I cycle

 

[SenorSuperdrol]

Caber has nothing to do with e2, so that’s out.

If we are talking most gains possible and decent reduction in chance of gyno. Than primo, mast & EQ, would win depending on individual response.

Obviously nolva or ralox would be the “most effective at controlling without crushing e2 and avoiding gyno” not something I’d take every cycle forever tho.

 

[Nidus]

Caber has nothing to do with e2, so that’s out.

If we are talking most gains possible and decent reduction in chance of gyno. Than primo, mast & EQ, would win depending on individual response.

Obviously nolva or ralox would be the “most effective at controlling without crushing e2 and avoiding gyno” not something I’d take every cycle forever tho.

E2 can cause High Prolactine and vice versa, not saying it will majorly increase but usually when one is elevated the other one can also be elevated and should be taken into account regardless

 

[SenorSuperdrol]

E2 can cause High Prolactine and vice versa, not saying it will majorly increase but usually when one is elevated the other one can also be elevated and should be taken into account regardless

That wasn’t the question. It was E2 and gyno.

There is no vice versa prolactin does not raise e2.

E2 can raise prolactin, it’s solely a one way street.

 

[Nidus]

That wasn’t the question. It was E2 and gyno.

There is no vice versa prolactin does not raise e2.

E2 can raise prolactin, it’s solely a one way street.

You are right, that was not OPs question thats why i wanted to directly reply to you.

There is breast cancer studies suggesting the opposite.
Prolactin and Estrogen Enhance the Activity of Activating Protein 1 in Breast Cancer Cells: Role of Extracellularly Regulated Kinase 1/2-Mediated Signals to c-fos - PMC (activation through the ERK1/2 and c-Fos pathways)

Prolactin and estrogen both activate MAPK/ERK pathways, which regulate cell proliferation and AP-1 activity which in return can amplify estrogen signaling and aromatization.
Given both activate and work through joint pathways, it is not just a one-way street, so gotta be cautious in the future.

I have seen that myself with higher/lower E levels and Prolactin levels on my own.

 

[SenorSuperdrol]

You are right, that was not OPs question thats why i wanted to directly reply to you.

There is breast cancer studies suggesting the opposite.
Prolactin and Estrogen Enhance the Activity of Activating Protein 1 in Breast Cancer Cells: Role of Extracellularly Regulated Kinase 1/2-Mediated Signals to c-fos - PMC (activation through the ERK1/2 and c-Fos pathways)

Prolactin and estrogen both activate MAPK/ERK pathways, which regulate cell proliferation and AP-1 activity which in return can amplify estrogen signaling and aromatization.
Given both activate and work through joint pathways, it is not just a one-way street, so gotta be cautious in the future.

I have seen that myself with higher/lower E levels and Prolactin levels on my own.

Noone cares about your one study “suggesting” or your anecdotal experience. Your argument is invalid. We know how prolactin works it’s not a mystery. A simple good search will correct you endlessly. Google “does prolactin raise estrogen”

 

[BigTomJ]

etc.

What is the most effecient and/or effective combination for controlling (not crushing) E2 and avoiding gyno? Say if you had to pick just one or two.

Aromasin and thats it

 

[Nidus]

Noone cares about your one study “suggesting” or your anecdotal experience. Your argument is invalid. We know how prolactin works it’s not a mystery. A simple good search will correct you endlessly. Google “does prolactin raise estrogen”

For someone who doesn't cares you seem very invested. So maybe you can provide me with medical papers or other scientifically proven information so that i can learn and understand more? By all means, correct me, i am here to gather more information and keen to learn new things!
Thank you!