Multidose Vial Adapter

[Sampei]

These may actually be better than the Braun spikes, we'll see. I switched from Easy Touch insulin syring to BD and the difference is substantial... stronger pin and effortlessly pierces skin. The syringes are more expensive though, but these spikes are actually lower cost than Braun.

I'll buy a few and let you know guys

 

[bigMoJo]

I prefer Nipro needle but not like BD are not good, they are both in my opinion top brand.

I was looking at Nipro syringes for larger gauge needles—made in Japan—they look to be a high quality product at the fraction of the BD price. This time around, I went with CarePoint syringes—made in Korea—there was a sale price on those and I couldn't pass up the price.

 

[Sampei]

I was looking at Nipro syringes for larger gauge needles—made in Japan—they look to be a high quality product at the fraction of the BD price. This time around, I went with CarePoint syringes—made in Korea—there was a sale price on those and I couldn't pass up the price.

can't go wrong with both BD or Nipro. Excellent brand, Terumo is not bad either.

GUYS! are these the nokor need or similar to it?

Acquista Ago da trasferimento BD Blunt Filter con filtro da 5 micron - 18G x 1 1/2" - 1,2 x 40 mm, Doctor Shop

www.doctorshop.it

it's blunted 18g with a 5micron filter should be good for filtering coring of stopper or any other thing right? very similar as a spike use isn't it?

@Ghoul @egruberman

 

[krvuxn]

I always use Nipro as well. Both needles and syringes.

 

[Ghoul]

can't go wrong with both BD or Nipro. Excellent brand, Terumo is not bad either.

GUYS! are these the nokor need or similar to it?

Acquista Ago da trasferimento BD Blunt Filter con filtro da 5 micron - 18G x 1 1/2" - 1,2 x 40 mm, Doctor Shop

www.doctorshop.it

it's blunted 18g with a 5micron filter should be good for filtering coring of stopper or any other thing right? very similar as a spike use isn't it?

@Ghoul @egruberman

Yes, but without the benefit of filtered venting of the vial.

 

[Sampei]

Yes, but without the benefit of filtered venting of the vial.

You don't really need filtered venting tho, don't you? I mean I never vent my oil vials. Peptide sure because of the vacuum

 

[bigMoJo]

You don't really need filtered venting tho, don't you? I mean I never vent my oil vials. Peptide sure because of the vacuum

I equalize pressure for both. Am I doing it wrong?

 

[Ghoul]

You don't really need filtered venting tho, don't you? I mean I never vent my oil vials. Peptide sure because of the vacuum

When you draw oil you're creating negative pressure. It's going to equalize one way or another, usually when you're pulling out the needle or inserting another.

 

[Ghoul]

"But I refilter / brew my gear and put it into sterile vials, there's no need for a filtered spike!"

Sterile Does Not Necessarily Mean Clean

Pharmaceutical products and devices entering the blood stream must be sterile and particle free. Sterilization does not ensure products are clean. Forensic analysis for identification of particles when they appear is necessary to determine the source.

www.mccrone.com

 

[Sampei]

When you draw oil you're creating negative pressure. It's going to equalize one way or another, usually when you're pulling out the needle or inserting another.

Yeah that is true, sometime it happens even when you draw you can see the bubble getting inside the vial while the oil enter the needle.

Is that an hazard for sterility?

 

[Sampei]

"But I refilter / brew my gear and put it into sterile vials, there's no need for a filtered spike!"

View attachment 300235

Sterile Does Not Necessarily Mean Clean

Pharmaceutical products and devices entering the blood stream must be sterile and particle free. Sterilization does not ensure products are clean. Forensic analysis for identification of particles when they appear is necessary to determine the source.

www.mccrone.com

I'll use those needles for my 10ml vials and use the filtered spike for my bigger vials I believe.

As using a filtered spike on a 10ml vial is really unaesthetic and my OCD can't stand it : (

 

[Ghoul]

Yeah that is true, sometime it happens even when you draw you can see the bubble getting inside the vial while the oil enter the needle.

Is that an hazard for sterility?

Yes, that's why multi dose vials are supposed to be used within 28 days of first penetration. It's not a huge risk, but each time unsterile air enters the vial the level of bacteria increases. That's why they include air filters for the spike vents, even for the ones that don't have fluid filters.

It's more critical for peptides than oils, as small amounts of bacteria introduced into the vial is more likely to degrade your peptide than make you sick, but it could. The less the better. It's up to you how far you want to go towards "medical grade" standards.

 

[Sampei]

Yes, that's why multi dose vials are supposed to be used within 28 days of first penetration. It's not a huge risk, but each time unsterile air enters the vial the level of bacteria increases. That's why they include air filters for the spike vents, even for the ones that don't have fluid filters.

It's more critical for peptides than oils, as small amounts of bacteria introduced into the vial is more likely to degrade your peptide than make you sick, but it could. The less the better. It's up to you how far you want to go towards "medical grade" standards.

Luckily I transfer all my peptide vials into a cartridge so not much air keep entering, I guess.

I wouldn't be able to use a cartridge with a spike tho I guess I have to make some compromises.

Yeah air into oils is not the biggest deal, as oil have BA and oil is not the greatest environment to have bacteria growing, water is instead.

What I'm more worried is coring of stopper etc so a drawing needle with a filter is definitely something I feel necessary if one is not using a spike

 

[bigMoJo]

Yes, that's why multi dose vials are supposed to be used within 28 days of first penetration. It's not a huge risk, but each time unsterile air enters the vial the level of bacteria increases. That's why they include air filters for the spike vents, even for the ones that don't have fluid filters.

It's more critical for peptides than oils, as small amounts of bacteria introduced into the vial is more likely to degrade your peptide than make you sick, but it could. The less the better. It's up to you how far you want to go towards "medical grade" standards.

The way I see it, it's worth the expense to keep everything as "sterile" as possible. Spikes, filters, whatever if it can "prevent" a serious health problem. The flip side is—at the least, going to the doctor and paying a years supply in co-pays, or—potentially, more if I'm hospitalized or need a "procedure." Not to mention the pain and downtime with all that.

 

[Sampei]

The way I see it, it's worth the expense to keep everything as "sterile" as possible. Spikes, filters, whatever if it can "prevent" a serious health problem. The flip side is—at the least, going to the doctor and paying a years supply in co-pays, or—potentially, more if I'm hospitalized or need a "procedure." Not to mention the pain and downtime with all that.

I never got an infection for ten years of injecting oils without a vented filter but I probably injected a shit load of rubber in the mean time. So if I have to compromise I believe a particle filter is 1000% more important than an air filter.

My personal opinion of course

 

[Ghoul]

I never got an infection for ten years of injecting oils without a vented filter but I probably injected a shit load of rubber in the mean time. So if I have to compromise I believe a particle filter is 1000% more important than an air filter.

My personal opinion of course

Most bacterial infections are asymptomatic.

It's very unlikely any of us using UGL gear aren't routinely injecting bacteria. It's certain we're injecting endotoxin.

They contribute to things like the accelerated development of arthritis ("reactive arthritis") and destruction of cartilage.

"In about 25% of patients, the infection can be asymptomatic. Diagnosis of the triggering infection is very helpful for the diagnosis of reactive arthritis. This is mainly achieved by isolating the triggering infection (stools, urogenital tract) by cultures (stool cultures for enteric microbes) or ligase reaction (Chlamydia trachomatis). However, after the onset of arthritis, this is less likely to be possible. "

Reactive arthritis or post-infectious arthritis? - PubMed

The term 'reactive arthritis' was first used in 1969 to describe the development of sterile inflammatory arthritis as a sequel to remote infection, often in the gastrointestinal or urogenital tract. The demonstration of antigenic material (e.g. Salmonella and Yersinia lipopolysaccharide), DNA...

pubmed.ncbi.nlm.nih.gov

 

[Ghoul]

PWID=people who inject drugs

"Infective bone and joint complications in PWID may originate from direct extension of infection from injection sites in adjacent soft tissues or, more commonly, due to bacteraemia and haematogenous seeding [16]."

The needle and the damage done: musculoskeletal and vascular complications associated with injected drug use - Insights into Imaging

Injected drug use is associated with a wide range of medical complications which are predominantly musculoskeletal and vascular in nature. Illicit drug use is increasing worldwide. Patients with complications of injected drug use often present in a non-specific manner without a reliable clinical...

insightsimaging.springeropen.com

 

[bigMoJo]

I never got an infection for ten years of injecting oils without a vented filter but I probably injected a shit load of rubber in the mean time. So if I have to compromise I believe a particle filter is 1000% more important than an air filter.

My personal opinion of course

I'm with you on the premise. I wouldn't have given it a thought if not for our discussions here. I think spending a couple hundred dollars for extra safety, even if its not a big issue, is worth it. Filter particles, great... plus air, even better.

Also, there is a big convenience with the spikes. Even the cartridges you previously mentioned.

 

[Justaguy99]

Any Canadians interested in spikes?
Wouldn't mind ordering but shipping sucks.

While we dont see eye to eye Ghoul this is good information.

 

[mknodc13]

Is it just me or are the sources for these filtered spikes mainly shipping from Europe?