Night sweats from HGH

[Kralteramon]

For sure, low bg can cause sweating and the increased adrenaline which releases when bg is low, increases fragmented sleep, can cause nightmares and vivid dreams. Increasing norepinephrine usually does this to sleep. It's partly why SNRI's and stuff like mirtazapine, cause vivid dreams.

Your response to tirz is rather strong so it is possible that this is the reason to your night sweats. And if you started tirz and GH at the same time, then you could have mistakenly attributed the effect to GH.

But maybe it's a combination of both. GH causing insulin resistance, without an immediate hyperglycemic response, lowering glucose availability, and tirz at the same time increasing insulin and decreasing hepatic glucose release ...

I've used Tirz before when I was not on AAS and in higher dosages and did not get the same effects, however my sleep did become more fragmented because of it. Maybe it's the stacked effect of the AAS (perticularely Nandrolone) and the Tirz. But the thing is, when I take out the HGH, my sleep improves masively (still on Tirz and AAS) as per last week's experiment.

But maybe it's a combination of both. GH causing insulin resistance, without an immediate hyperglycemic response, lowering glucose availability, and tirz at the same time increasing insulin and decreasing hepatic glucose release ...

This sounds like a reasonable theory to me as well. Might be that my cells are not getting enough glucose because of this double whammy effect. However I'm still not sure if this would really be it. I'm going to keep experimenting to see if I can find more evidence of the culprit.

 

[Jin23]

I've used Tirz before when I was not on AAS and in higher dosages and did not get the same effects, however my sleep did become more fragmented because of it. Maybe it's the stacked effect of the AAS (perticularely Nandrolone) and the Tirz. But the thing is, when I take out the HGH, my sleep improves masively (still on Tirz and AAS) as per last week's experiment.

But maybe it's a combination of both. GH causing insulin resistance, without an immediate hyperglycemic response, lowering glucose availability, and tirz at the same time increasing insulin and decreasing hepatic glucose release ...

This sounds like a reasonable theory to me as well. Might be that my cells are not getting enough glucose because of this double whammy effect. However I'm still not sure if this would really be it. I'm going to keep experimenting to see if I can find more evidence of the culprit.

GH fragments sleep as is, no matter your BG management. So if you want to sleep normally, stop using it before bed. I was talking only about the night sweats ...

 

[lilhawk]

I can attest to the fragmented sleep with HGH. I do have sleep apnea and wear a CPAP every night and have been for years. I've been taking 6iu of Serostim every night before bed and I have no problem falling asleep, but I wake up after about 3-4 hours of sleep then struggle to go back to sleep the rest of the night. I am going to switch back to injecting the GH in the morning and pre workout or post workout as when I was doing this I had no trouble sleeping through the night. However it does still make me sleepy during the day doing it this way. I am also using test and primo. My twin brother takes the same dose of GH nightly and says he sleeps like a rock. He has not been diagnosed with sleep apnea.

 

[AlexDavis43]

If sleep quality deteriorates on GH, you can try different dose timing, but if that doesn't work, it's fine to drop GH.

Good sleep quality is more of a game changer than using GH.

 

[Kralteramon]

Morning and afternoon split worked. No more sweating during the night and frequent waking up! I'm doing the full 3iu dose in the morning now see how that feels. Snoring does seem to be up so I'm going to get a sleep study done. Also because I need to gain 10kg to hit contest weight and some more on top because I'm not going to bulk with 6% fat .

 

[Kralteramon]

I have some added information about what I think is going on. I have a gene variation of the COMT gene (worrier met/met) which causes a slower breakdown of catecholamines in my body (adrenaline & noradrenaline included). So my theory is that because HGH enhances beta-adrenergic receptor activity, making my body more responsive to adrenaline & noradrenaline, I get a greater effect from them, hence why the increase in my RHR is so pronounced with lower doses of HGH. I also have a gene that causes a stronger response to IGF-1 (rs35767 (C;C)). Hence this combination makes me much more susceptible to negative side effects (and I also probably need less HGH to reach good IGF1 levels). I'm going to add SAMe and L theanine to my supplement protocol to improve catecholamine removal and see if that helps. Also have blood work coming up, if E2 is on the high side, I will see if toning it down will help as well since estrogen also makes my COMT type symptoms worse. Also testing IGF-1.

 

[Ateam2023]

I have some added information about what I think is going on. I have a gene variation of the COMT gene (worrier met/met) which causes a slower breakdown of catecholamines in my body (adrenaline & noradrenaline included). So my theory is that because HGH enhances beta-adrenergic receptor activity, making my body more responsive to adrenaline & noradrenaline, I get a greater effect from them, hence why the increase in my RHR is so pronounced with lower doses of HGH. I also have a gene that causes a stronger response to IGF-1 (rs35767 (C;C)). Hence this combination makes me much more susceptible to negative side effects (and I also probably need less HGH to reach good IGF1 levels). I'm going to add SAMe and L theanine to my supplement protocol to improve catecholamine removal and see if that helps. Also have blood work coming up, if E2 is on the high side, I will see if toning it down will help as well since estrogen also makes my COMT type symptoms worse. Also testing IGF-1.

You are hell bent on using hgh , kudos for the effort,,

 

[krusty28]

I have some added information about what I think is going on. I have a gene variation of the COMT gene (worrier met/met) which causes a slower breakdown of catecholamines in my body (adrenaline & noradrenaline included). So my theory is that because HGH enhances beta-adrenergic receptor activity, making my body more responsive to adrenaline & noradrenaline, I get a greater effect from them, hence why the increase in my RHR is so pronounced with lower doses of HGH. I also have a gene that causes a stronger response to IGF-1 (rs35767 (C;C)). Hence this combination makes me much more susceptible to negative side effects (and I also probably need less HGH to reach good IGF1 levels). I'm going to add SAMe and L theanine to my supplement protocol to improve catecholamine removal and see if that helps. Also have blood work coming up, if E2 is on the high side, I will see if toning it down will help as well since estrogen also makes my COMT type symptoms worse. Also testing IGF-1.

if you decide your done 'll take your GH if you wanna get rid of it lol just pm me lol

 

[Kralteramon]

It's nice to have a sounding board to project my ideas. Thanks for tuning in, appreciate it. When I go for something, I go all the way even if turns out to be a dead end. I plan on starting/keeping a log of my journey to my first show on this forum soon. You guys make this place feel like home!

 

[Jin23]

I have some added information about what I think is going on. I have a gene variation of the COMT gene (worrier met/met) which causes a slower breakdown of catecholamines in my body (adrenaline & noradrenaline included). So my theory is that because HGH enhances beta-adrenergic receptor activity, making my body more responsive to adrenaline & noradrenaline, I get a greater effect from them, hence why the increase in my RHR is so pronounced with lower doses of HGH. I also have a gene that causes a stronger response to IGF-1 (rs35767 (C;C)). Hence this combination makes me much more susceptible to negative side effects (and I also probably need less HGH to reach good IGF1 levels). I'm going to add SAMe and L theanine to my supplement protocol to improve catecholamine removal and see if that helps. Also have blood work coming up, if E2 is on the high side, I will see if toning it down will help as well since estrogen also makes my COMT type symptoms worse. Also testing IGF-1.

You are probably going to be disappointed with SAMe as it increases neurotransmitter synthesis. It feels very similar to an MAOI like moclobemide, ie. serotonin + norepinephrine. In research, for instance, it was shown to have same effectives for depression as antidepressants.

 

[Kralteramon]

You are probably going to be disappointed with SAMe as it increases neurotransmitter synthesis. It feels very similar to an MAOI like moclobemide, ie. serotonin + norepinephrine. In research, for instance, it was shown to have same effectives for depression as antidepressants.

Let's see. I'm happy to experiment. It's supposed to increase COMT activity which I lack with my gene. So catecholamines stay in my system longer before they get broken down through COMT enzymes. Let's see i don't think it's a miracle cure anyway.