PCT - Lets get it ironed out (Dr Scally?)

While I agree SERMs are the DOC for gynecomastia prophylaxis and treatment of existing disease, they reduce the possibility of developing gynecomastia yet do NOT eliminate that possibility.

The only means of eliminating that particular complication of AAS use may only be accomplished by surgical resection of the estrogen dependent ducal tissue.

I only mention this because some BB are quite surprised when gynecomastia develops in spite of SERM therapy.

Jim

That's interesting and new to me Doc! My understanding is that SERMs will block 100% of E receptors therefore no chance of gyno. If I'm not mistaken, Dr. Scally used this in his castle analogy that was mentioned in one of his posts.
 
Proper PCT Protocol

PCT should only begin when the body is in an environment to stimulate LH and FSH secretion. In the case of testosterone this environment is achieved once TT begins to dip below pre cycle TT levels. Therefore not only to judge when pct has been successful but also to determine when pct should begin Pre-cycle blood levels should be taken.

How do we determine when TT levels fall below baseline aside from experiencing side effects or getting blood drawn every week?

As we know TT is directly related with the amount of exogenous testosterone we administer. In TRT studies it is generally excepted that a 100mg shot of testosterone enanthate/cyp will put blood levels at around 800-900ng/dl.
We can thus use this conversion with decent accuracy to judge at what mg TT levels will fall below baseline. (The conversion ratio somewhat lessens as doses increase therefore we should air on the side of caution when determining the optimal test mg target)

For example if pre-cycle levels are 500ng/dl then PCT should only begin when exogenous test falls to roughly 50mg. This will put TT in the 400-500ng/dl range and thus in a state where HPTA stimulation of FSH and LH release begins to become possible.

Now that we understand how to determine optimal Mg range of ex Test for HPTA restoration we must now find the length of time required to reach said levels after the last injection. To do this we must first understand Half lives of the varying esters and the variation they can have with each individual's physiology. Some users metabolize AAS more quickly or more slowly than others therefore we can only identify an average. Ill give one practical example of the commonly used ester Enanthate.

Enanthate has a half life of 5 days +/- 2.5 days (I will use a 7 day calculation to air on the side of caution)

A 12wk cycle of test e at 500mg per week will put ex Test at around 1000mg
(500mg+250+125+62.5+31.25 etc = 1000mg)

This means it will take 5 half lives to reach ex test at or below 50mg therefore time between last injection and start of PCT is 35 days.

It would be worthwhile to determine your own metabolization rate by taking a blood test after the 4th AVERAGE half life has passed. (In this case it would be at 20 days) If TT levels are significantly above or below 400-500ng/dl you can determine YOUR half life.

Now that we understand how to accurately calculate a PCT start date based on our own physiology, what should an effective pct consist of?

Here is Dr. Scally's PCT protocol. (His experience and expertise speaks for itself)

Days
1-20 HCG 2000 IU EOD
1-35 Clomiphene 50mg morning and night
1-45 Tamoxifen 20 mg morning and night

This PCT will give you the best chance at achieving and maintaining pre cycle TT levels after cessation of treatment for any and all AAS cycles. This is a protocol he uses for his TRT patients.

( this is not part of the the post, Dr Jim do you believe this protocol is essentially overkill for the average AAS user considering this was designed for TRT patients? I have a feeling you could perform an equally effective pct with half those doses and slightly less time. Dr scaly actually mentioned that most AAS users would only need a 1000iu dose. I do not want to stray from this pct without your approval. What would you recommend for pct considering a max cycle length of 18 weeks? Ok back to the post!)

Post pct bloods should be taken approximately 2 weeks after cessation of treatment. (not part of the post, I'm not entirely sure on this what would you recommend Dr. ?) to ensure restoration has been achieved without further aid from SERM's. If restoration has not been achieved extend Clomiphene and Tamoxifen treatment another 30 days. (This is just a suggestion I'm not exactly sure on this either)

A largely overlooked factor that can greatly aid in maintaining gains, reducing HPTA shutdown length or extending a cycle without lengthening HPTA shutdown is switching from Long ester AAS to short ester AAS toward the end of the cycle. When done correctly this reduces the amount of time that users must wait to start PCT and increases the amount of time TT levels stay supra-physiological.

Here is a practical example of how to perform a switch to Test P from Test E
for a 12 week cycle.

First we must calculate our pct start date. For this example we will be using 750mg test e a week. With Ex test at about 1500 5 half lives have to pass to reach below 50mg. A PCT start date of 35 days is again warranted. Therefore we will start test p injections 35 days or 5 weeks before the end of the cycle.

Week 1-7 Test e 750mg
Week 8 Test p 400mg
Week 9 Test p 600mg
Week 10-12 Test p 700mg

Test p half life 2 days +/- 18hours (I will use a 2.5 day calculation)

PCT start 7 days (28 days shorter!!!)

Tapering the test p injections upward in this fashion will ensure that TT levels do not spike dramatically when the shorter more quickly metabolized half life is introduced.

One compound that should be taken into extreme consideration for pct start dates is Deca-Durabolin. Deca is somewhat unique in the fact that a normal half life calculation cannot be used.

Deca has a half life of 10 days +/- 5days BUT studies have shown that Deca's suppressive metabolites will impair HPTA function long after the parent hormone has cleared.

The Study: Two hypogonadal former anabolic steroid users were studied. Normal levels of LH are >3.6 IU/L and Testosterone are 300-1000 ng/dl. Former anabolic steroid users often have suppressed levels of both.

The Results: Subject #1 is a 6', 206lb former user of 500-2000+ Milligrams per week of anabolics. His baseline numbers were: LH<1IU/L, Test=191ng/dl. This suject underwent a 32 day treatment of 2500 IU of HCG every 4 days, 50 mg of clomid 2 times per day, and 10 mg nolvadex per day. 15 days after treatment his numbers were: LH=5.2IU/L, Test=1072 ng/dl.

Subject #2 is a 5'10", 184lb male who used 400 mg per week of nandrolone . His baseline numbers were: LH<1IU/L, Test=45ng/dl. This subject's 32 day treatment consisted of 2500 IU of HCG every 4 days, 50 mg of clomid 2 times per day, and 10 mg nolvadex per day. There was no change. He underwent another treatment consisting of 60 days of 5000 IU of HCG every 4 days for 4 injections, then 2500 IU every 4 days for 4 injections, 50 mg of clomid 2 times per day, and 10 mg nolvadex per day. Still, no change. For the next 32 days, this subject received 5000 IU of HCG every other day for 6 injections, then 2500 IU every other day for 6 injections given with 150 IU of menotropins, 50 mg of clomid 2 times per day, and 10 mg nolvadex 2 times per day. 15 days after treatment his numbers were: LH=9.8IU/L, Test=507 ng/dl.(20)

Over 150 days of aggressive pct and TT levels barely surpass 500ng/dl with an LH value that is 3x higher than normal?

This is indicative of continued suppression even after such extreme treatment over an incredible length of time.

If you must include deca in your cycle and I cannot convince you otherwise a period of at least 12 weeks should pass between last injection and PCT even at minimal doses such as 250mg per week.

Ok so what do you guys think? What am I missing?
Keep in mind I cannot spoon feed every little detail because I will not let the post exceed 1 page length.
 
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Proper PCT Protocol

PCT should only begin when the body is in an environment to stimulate LH and FSH secretion. In the case of testosterone this environment is achieved once TT begins to dip below pre cycle TT levels. Therefore not only to judge when pct has been successful but also to determine when pct should begin Pre-cycle blood levels should be taken.

How do we determine when TT levels fall below baseline aside from experiencing side effects or getting blood drawn every week?

As we know TT is directly related with the amount of exogenous testosterone we administer. In TRT studies it is generally excepted that a 100mg shot of testosterone enanthate/cyp will put blood levels at around 800-900ng/dl.
We can thus use this conversion with decent accuracy to judge at what mg TT levels will fall below baseline. (The conversion ratio somewhat lessens as doses increase therefore we should air on the side of caution when determining the optimal test mg target)

For example if pre-cycle levels are 500ng/dl then PCT should only begin when exogenous test falls to roughly 50mg. This will put TT in the 400-500ng/dl range and thus in a state where HPTA stimulation of FSH and LH release begins to become possible.

Now that we understand how to determine optimal Mg range of ex Test for HPTA restoration we must now find the length of time required to reach said levels after the last injection. To do this we must first understand Half lives of the varying esters and the variation they can have with each individual's physiology. Some users metabolize AAS more quickly or more slowly than others therefore we can only identify an average. Ill give one practical example of the commonly used ester Enanthate.

Enanthate has a half life of 5 days +/- 2.5 days (I will use a 7 day calculation to air on the side of caution)

A 12wk cycle of test e at 500mg per week will put ex Test at around 1000mg
(500mg+250+125+62.5+31.25 etc = 1000mg)

This means it will take 5 half lives to reach ex test at or below 50mg therefore time between last injection and start of PCT is 35 days.

It would be worthwhile to determine your own metabolization rate by taking a blood test after the 4th AVERAGE half life has passed. (In this case it would be at 20 days) If TT levels are significantly above or below 400-500ng/dl you can determine YOUR half life.

Now that we understand how to accurately calculate a PCT start date based on our own physiology, what should an effective pct consist of?

Here is Dr. Scally's PCT protocol. (His experience and expertise speaks for itself)

Days
1-20 HCG 2000 IU EOD
1-35 Clomiphene 50mg morning and night
1-45 Tamoxifen 20 mg morning and night

This PCT will give you the best chance at achieving and maintaining pre cycle TT levels after cessation of treatment for any and all AAS cycles. This is a protocol he uses for his TRT patients.

( this is not part of the the post, Dr Jim do you believe this protocol is essentially overkill for the average AAS user considering this was designed for TRT patients? I have a feeling you could perform an equally effective pct with half those doses and slightly less time. Dr scaly actually mentioned that most AAS users would only need a 1000iu dose. I do not want to stray from this pct without your approval. What would you recommend for pct considering a max cycle length of 18 weeks? Ok back to the post!)

Post pct bloods should be taken approximately 2 weeks after cessation of treatment. (not part of the post, I'm not entirely sure on this what would you recommend Dr. ?) to ensure restoration has been achieved without further aid from SERM's. If restoration has not been achieved extend Clomiphene and Tamoxifen treatment another 30 days. (This is just a suggestion I'm not exactly sure on this either)

A largely overlooked factor that can greatly aid in maintaining gains, reducing HPTA shutdown length or extending a cycle without lengthening HPTA shutdown is switching from Long ester AAS to short ester AAS toward the end of the cycle. When done correctly this reduces the amount of time that users must wait to start PCT and increases the amount of time TT levels stay supra-physiological.

Here is a practical example of how to perform a switch to Test P from Test E
for a 12 week cycle.

First we must calculate our pct start date. For this example we will be using 750mg test e a week. With Ex test at about 1500 5 half lives have to pass to reach below 50mg. A PCT start date of 35 days is again warranted. Therefore we will start test p injections 35 days or 5 weeks before the end of the cycle.

Week 1-7 Test e 750mg
Week 8 Test p 400mg
Week 9 Test p 600mg
Week 10-12 Test p 700mg

Test p half life 2 days +/- 18hours (I will use a 2.5 day calculation)

PCT start 7 days (28 days shorter!!!)

Tapering the test p injections upward in this fashion will ensure that TT levels do not spike dramatically when the shorter more quickly metabolized half life is introduced.

One compound that should be taken into extreme consideration for pct start dates is Deca-Durabolin. Deca is somewhat unique in the fact that a normal half life calculation cannot be used.

Deca has a half life of 10 days +/- 5days BUT studies have shown that Deca's suppressive metabolites will impair HPTA function long after the parent hormone has cleared.

The Study: Two hypogonadal former anabolic steroid users were studied. Normal levels of LH are >3.6 IU/L and Testosterone are 300-1000 ng/dl. Former anabolic steroid users often have suppressed levels of both.

The Results: Subject #1 is a 6', 206lb former user of 500-2000+ Milligrams per week of anabolics. His baseline numbers were: LH<1IU/L, Test=191ng/dl. This suject underwent a 32 day treatment of 2500 IU of HCG every 4 days, 50 mg of clomid 2 times per day, and 10 mg nolvadex per day. 15 days after treatment his numbers were: LH=5.2IU/L, Test=1072 ng/dl.

Subject #2 is a 5'10", 184lb male who used 400 mg per week of nandrolone . His baseline numbers were: LH<1IU/L, Test=45ng/dl. This subject's 32 day treatment consisted of 2500 IU of HCG every 4 days, 50 mg of clomid 2 times per day, and 10 mg nolvadex per day. There was no change. He underwent another treatment consisting of 60 days of 5000 IU of HCG every 4 days for 4 injections, then 2500 IU every 4 days for 4 injections, 50 mg of clomid 2 times per day, and 10 mg nolvadex per day. Still, no change. For the next 32 days, this subject received 5000 IU of HCG every other day for 6 injections, then 2500 IU every other day for 6 injections given with 150 IU of menotropins, 50 mg of clomid 2 times per day, and 10 mg nolvadex 2 times per day. 15 days after treatment his numbers were: LH=9.8IU/L, Test=507 ng/dl.(20)

Over 150 days of aggressive pct and TT levels barely surpass 500ng/dl with an LH value that is 3x higher than normal?

This is indicative of continued suppression even after such extreme treatment over an incredible length of time.

If you must include deca in your cycle and I cannot convince you otherwise a period of at least 12 weeks should pass between last injection and PCT even at minimal doses such as 250mg per week.

Ok so what do you guys think? What am I missing?

this is great man...but we're still gonna get lazy assholes who won't read it :mad:
 
this is great man...but we're still gonna get lazy assholes who won't read it :mad:

I know its the sad truth...but every time someone asks a question all of the senior members should just post a link to this page.

It's only 1 fucking page of reading for a comprehensive guide to pct.
 
I know its the sad truth...but every time someone asks a question all of the senior members should just post a link to this page.

It's only 1 fucking page of reading for a comprehensive guide to pct.

i think that you should have made a new thread so it can be stickied
 
i think that you should have made a new thread so it can be stickied

That's what I intend to do but I would like to get the communities input and mainly the Dr.'s before I create the thread and ask Millard to sticky it.

This is basically my rough draft.

I know it looks pretty good for a rough draft ;) :cool:
 
IQR
The castle analogy your referring to was used by DOC to compare the efficacy of SERMS (the gates) to that of AI (soliders attempting to gain access).

The thread arose because some BB believe AIs are first line for gyneco (in spite of limited data) rather than SERMs.

His point was, and I certainly agree, is that if you can "block the gates" of the estrogen receptor the need for an AI becomes a form of second line treatment SHOULD SERMS FAIL,

Thus when SERMSs fail as adequate therapy for gynecomastia an AI should be added, providing the SERM therapy has been optimized.

Jim
 
Ape, you are the man Bro! Having to also mentioned Deca's effects makes this post the best PCT read I have EVER come across. It's detailed yet to the point and easy to read. However, Scally's PCT is just an overkill and I hope that Dr. Jim can provide his thoughts on this. The protocol suggested, as you had mentioned, is for TRT patients... it will deter people from following such regime given the costs associated with such dosages and length of administration. If this is the way to go, I have absolutely no problem following this protocol hence my obsession with PCT. However, another look would be of great value for others! Dr. Jim?

The study for Deca was conducted using only two subjects...do you see the problem? Any other studies? In addition, the study also mentioned that "Former anabolic steroid users often have suppressed levels of both". What kind of "former anobolic steroid users" are we talking about here? Abusers or those that might go on a max of two cycles per year and won't exceed 1g of anabolic with a proper PCT?

Once again, a great post and if this doesn't deserve a sticky once Jim provides his thoughts, I don't know what will...

IRQ
 
IQR
The castle analogy your referring to was used by DOC to compare the efficacy of SERMS (the gates) to that of AI (soliders attempting to gain access).

The thread arose because some BB believe AIs are first line for gyneco (in spite of limited data) rather than SERMs.

His point was, and I certainly agree, is that if you can "block the gates" of the estrogen receptor the need for an AI becomes a form of second line treatment SHOULD SERMS FAIL,

Thus when SERMSs fail as adequate therapy for gynecomastia an AI should be added, providing the SERM therapy has been optimized.

Jim

He dr could you answer the new questions I had regarding the pct protocol post..I would like to post it tonight but would appreciate your input once more.
 
i think that you should have made a new thread so it can be stickied

This post is worth 979726597893764172364 Hrs at the gym (based on a scientific calculation [:o)]). Start reading folks otherwise you have no business using AAS. with the use of AAS comes great responsibility.

IRQ
 
IQR
The castle analogy your referring to was used by DOC to compare the efficacy of SERMS (the gates) to that of AI (soliders attempting to gain access).

The thread arose because some BB believe AIs are first line for gyneco (in spite of limited data) rather than SERMs.

His point was, and I certainly agree, is that if you can "block the gates" of the estrogen receptor the need for an AI becomes a form of second line treatment SHOULD SERMS FAIL,

Thus when SERMSs fail as adequate therapy for gynecomastia an AI should be added, providing the SERM therapy has been optimized.

Jim

who's IQR? :cool: :p

Thanks Jim, however, blocking the gates means no intruders. Is there a study that shows users suffering from gyno while using SERMs on cycle? If so, I stand corrected...
 
Ape, you are the man Bro! Having to also mentioned Deca's effects makes this post the best PCT read I have EVER come across. It's detailed yet to the point and easy to read. However, Scally's PCT is just an overkill and I hope that Dr. Jim can provide his thoughts on this. The protocol suggested, as you had mentioned, is for TRT patients... it will deter people from following such regime given the costs associated with such dosages and length of administration. If this is the way to go, I have absolutely no problem following this protocol hence my obsession with PCT. However, another look would be of great value for others! Dr. Jim?

The study for Deca was conducted using only two subjects...do you see the problem? Any other studies? In addition, the study also mentioned that "Former anabolic steroid users often have suppressed levels of both". What kind of "former anobolic steroid users" are we talking about here? Abusers or those that might go on a max of two cycles per year and won't exceed 1g of anabolic with a proper PCT?

Once again, a great post and if this doesn't deserve a sticky once Jim provides his thoughts, I don't know what will...

IRQ

way to kiss that ass newb! good man, apeshit put in some work for ya
 
way to kiss that ass newb! good man, apeshit put in some work for ya

Don't get too comfortable with your language with me please. I don't know you and don't call me newb as I have been in the field of BB for a long time but relatively new to AAS. Ape is not only putting in the work for me but is doing so for the whole community. His post will help a lot of people with this crucial part of a cycle. Thanking him is the appropriate thing to do and for those that have followed this thread should also be thankful for his time and experience in this field.

Got it? Good!
 
Don't get too comfortable with your language with me please. I don't know you and don't call me newb as I have been in the field of BB for a long time but relatively new to AAS. Ape is not only putting in the work for me but is doing so for the whole community. His post will help a lot of people with this crucial part of a cycle. Thanking him is the appropriate thing to do and for those that have followed this thread should also be thankful for his time and experience in this field.

Got it? Good!

anyone who doesn't know basic PCT protocol is a noob. got it? good.
 
WHAT??? ARE YOU SERIOUS???!!! there is a BASIC PCT PROTOCOL??? WHERE??!!! :confused:

what a waste of time this thread is (being sarcastic) ...

I'm very sure you came to this world knowing everything. I'm an example of how people should educate themselves to ensure the safest way to use AAS...and you are an example of yet another loser behind a screen demotivating those wanting to learn and help others.

In any case, I will not pollute this thread or waste my time with you as I have come across your other posts in other threads (what a great contributor you are).

I hope that you use proper language with others.
 
WHAT??? ARE YOU SERIOUS???!!! there is a BASIC PCT PROTOCOL??? WHERE??!!! :confused:

what a waste of time this thread is (being sarcastic) ...

I'm very sure you came to this world knowing everything. I'm an example of how people should educate themselves to ensure the safest way to use AAS...and you are an example of yet another loser behind a screen demotivating those wanting to learn and help others.

In any case, I will not pollute this thread or waste my time with you as I have come across your other posts in other threads (what a great contributor you are).

I hope that you use proper language with others.

no i didnt know shit when i came here...but when i came here they were a lot harder on me than they were you and i knew my place...my point being don't get all tied up in a knot and tell me how i should approach you when no harm was done.
 
WHAT??? ARE YOU SERIOUS???!!! there is a BASIC PCT PROTOCOL??? WHERE??!!! :confused:

what a waste of time this thread is (being sarcastic) ...

I'm very sure you came to this world knowing everything. I'm an example of how people should educate themselves to ensure the safest way to use AAS...and you are an example of yet another loser behind a screen demotivating those wanting to learn and help others.

In any case, I will not pollute this thread or waste my time with you as I have come across your other posts in other threads (what a great contributor you are).

I hope that you use proper language with others.

yeh if you would have looked at some of my threads like you said you did maybe you would have gotten an idea for a PCT instead of making apeshit do all the work for you.
 
APE,
The answer to your question (before I took you on a 3 day tour of what I believe to be true, I think, lol) is yes, for those reasons I expounded upon earlier in this thread, a SEVEN DAY HALF LIFE for BOTH T-c AND T-e are more appropriate.

BEST :)
JIMMY
 
APE,
The answer to your question (before I took you on a 3 day tour of what I believe to be true, I think, lol) is yes, for those reasons I expounded upon earlier in this thread, a SEVEN DAY HALF LIFE for BOTH T-c AND T-e are more appropriate.

BEST :)
JIMMY

I appreciate that answer and have already adjusted per your recommendations in the new post. There are new questions in the new full rough draft, specifically the dosages of SERM's and HCG during pct. I thought dr scallys recommendations were a bit overkill for AAS users considering his pct is designed for TRT patients. What are your thoughts on

HCG 2000iu EOD 1-20
Clomid 50mg morning and night 1-35
Nolva 20mg morning and night. 1-45

I was thinking

HCG 2000 IU EOD 1-14
Clomid 25mg morning and night 1-28
Nolva 10mg morning and night 1-35

I feel there are many more users who would find this acceptable and doable in terms of cost and time while still being effective. (I understand these should not be factors but they are)

Would you agree with this PCT if not would you use dr scallys or something else?
 
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yeh if you would have looked at some of my threads like you said you did maybe you would have gotten an idea for a PCT instead of making apeshit do all the work for you.

Haha he is definitely out of line coming back at you in that manner for just calling him a newb (which you are Irq) shit I'm still a newb. But I did not do this just for him but for the whole community. That being said lets not clutter the thread anymore regardless of who is out of line or not.
 
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