MESO-Rx Sponsor Pharmacom Labs officials and our Basicstero.com store

[PHL Official]

Farestos: Toremifene from Pharmacom Labs

Analytic testing performed by Janoshik.

RESULTS:

1. Qualitative analysis: the sample contains the active ingredient: Toremifene Citrate.
2. Quantitative analysis showed the content of active ingredient: 19.92 mg.

Analysis conducted: 16 June 2023

 

[broilovesushi]

Anyone use their injectable Winstrol before? and do we also have any newer lab testing on it? Thank you.

 

[RThoads]

Anyone use their injectable Winstrol before? and do we also have any newer lab testing on it? Thank you.

I have not seen any lab analysis of it.
It may be difficult to get an analysis because it is a water suspension NOT an oil (it is micronized crystals suspended in water, a heterogeneous mixture, NOT a homogeneous solution dissolved in oil).
Therefore, there is no uniform solution concentration to test.
It is different than most intestable products and you cannot mix it is the same barrel with oils.
Also, keep the fact it is a suspension in mind when considering the product and be sure that you understand suspensions.

https://pharmacomlabs.com/product/21

Personally, unless there is some very specific reason a suspension is desired, I'd simply opt for the oral.

 

[RThoads]

Check the Facts for Yourself: Basicstero is the Direct from Pharmacom Labs Store.

You can check the authenticity of the Basicstero.ws store by entering “Basicstero.ws” in the "DEALERS" section on Pharmacom Labs official site.

Check it for yourself:
✔ Pharmacom Labs - Dealers Site

All products come directly from the manufacturer Pharmacom Labs!

https://basicstero.ws/

Important: This source does not take orders via email.
If anyone tries to get you to place a new order via email or a site/link other than the basicstero.ws official store, it may be a scam.
BEWARE OF SCAMMERS! ALL ORDERS SHOULD ONLY BE PLACED AND PROCESSED THROUGH THE CHECKOUT PROCESS IN THE OFFICIAL STORE!

 

[RAre]

Any idea when domestic warehouse will restock?

 

[RThoads]

Any idea when domestic warehouse will restock?

Hi, restocking usually happens every few months....

In the past it was stated that restocking usually happens every few months.
Usually there is an announcement posted when there is a significant restock.

 

[edjohn88]

Mine has been 15 days without tracking number. I'd appreciate a look.

 

[PHL Official]

Mine has been 15 days without tracking number. I'd appreciate a look.

Hello! I'd like to help you, but to do that you have to PM me your order number.

 

[RThoads]

Mine has been 15 days without tracking number. I'd appreciate a look.

There is nothing unusual here -- it can takes a couple weeks before tracking is uploaded.

When the source uploads the tracking numbers for your order, you will be able to see the tracking info on the order status/details page.

This usually takes from a few days to a few weeks depending upon the postal service situation and workload of the source's staff.
In my experience the source prefers to wait until packs have passed the country of origin before uploading tracking information so that the warehouse staff and shippers etc. may enjoy as much anonymity and safety as possible.

Most likely, the source simply has not yet uploaded the batch of tracking numbers that your shipment is in. It sounds like your order may have only very recently been shipped out in the past week or two (you mentioned it has only been 15 days).

Also, check the messenger in your Basicstero account for any updates.

 

[RThoads]

I checked this morning and both Warehouse Promos are still active.
See the post linked below for more details:
Reminder: Basicstero currently has Two PROMOS active

 

[RThoads]

How are things going?
Have any of you tried the new Pharmacom Labs fat-loss product TESOS yet?
What was your experience like with it?

TESOS – An Exciting NEW Fat-Loss Product from Pharmacom Labs! – is Now Available in the Basicstero Store.

https://basicstero.ws/fat-loss/tesos

This innovative Oral-Line Fat-Loss product is currently offered as a 50 count blister strip of 0.5 mg tablets (1 BLISTER, 50 PILLS).

Tesofensine Information:
Tesofensine is a unique new generation Triple Serotonin Norepinephrine Dopamine Reuptake Inhibitor (SNDRI).
SNDRI belong to the class of psychoactive antidepressants. They affect neurotransmitters in the brain, exactly serotonin, norepinephrine and dopamine. Tesofensin affects the brain qualitatively, helping a person to feel maximum saturation during eating, and reduce appetite significantly.
Tesofensin was originally developed and patented by NeuroSearch A/S (Denmark) to cure Parkinson's and Alzheimer's diseases.
• acts centrally, suppress appetite, regulate the availability of dopamine receptors and stimulate α1-adrenergic receptors.
• appetite decreases within 14 days, there is a higher level of satiety and less desire to eat.
• increases significantly fat oxidation and reduces adipose tissue.
• improves the level of insulin sensitivity, which leads to higher glucose metabolism.
• alters the expression of dopaminergic receptors in the striatum of the brain, as well as their binding.
• the energy consumption increases greatly within 14 days.
• The drug has a long half-life, which is 8-9 days, and metabolized mainly in the liver by CYP3A4 to the disalkyl metabolite M1 (NS-2360), which is the only metabolite found in human blood plasma.

Chemical name: (1R,2R,3S,5S)-3-(3,4-dichlorophenyl)-2-(ethoxymethyl)-8-methyl-8-azabicyclo[3.2.1]octane
Formula: C17H23Cl2NO
Anabolic activity index: not a steroid
Androgenic activity index: not a steroid
ACTIVE HALF-LIFE: 9 days
CLASSIFICATION: psychoactive antidepressants.
DOSAGE: 0.25 mg -1 mg
ACNE: no
WATER RETENTION: no
HBR: Perhaps
HEPATOXITY: Low
AROMATIZATION: no

The Basicstero Team hopes this NEW Pharmacom Labs Fat-Loss product will help you reach your goals!

 

[Pharmacom Support]

For your convenience, Basicstero has added a "messages" section on the store website where you can contact customer support for any questions or help you need (such as with payment, ordering, account, etc.).​

​

Now you can contact Basicstero’s customer support directly via internal messenger in your account instead of filling out a form on the “Contact Us” page.​

​

Basicstero has also added a “consultations” section to the store website for customers that may have questions about pharma plan/protocol, health, and any other questions for our sports medical professional support!​

​

You can find these new options on the top bar when logged into your Basicstero account.​

 

[RThoads]

Toremifene (Fareston) – A More Modern SERM – is Available in the Basicstero Store

Toremifene Citrate is a selective estrogen receptor modulator (SERM) derived from triphenylethylene. It was patented and approved in Europe in the mid 1990's to treat metastatic ER+ breast cancer in postmenopausal women. Toremifene (Fareston) is an analogue of Tamoxifen and Clomid which can be used to replace these older compounds.

In bodybuilding toremifene citrate is used by men as a drug for post-cycle therapy (PCT) to counteract and/or block some of the effects of excessive estradiol in the body as a result of aromatization of various androgens used. In particular, toremifene is used to restore levels of endogenous testosterone in blood as well as to prevent the estrogen-related side effect of gynecomastia.
In its chemical structure toremifene is very similar to tamoxifen and clomiphene. However, toremifene is a new generation drug and has less toxic side effects than tamoxifen.

For a more effective boost in testosterone production toremifene dosage should be in the range of up to 120 mg per day. This dose can be maintained for a first week of PCT; then, 100mg/day for the second week of PCT; and, finally 60mg/day for the remaining 3 – 4 weeks of PCT. Of course, exact dosages should be determined individually based on blood work results.

This innovative SERM is currently available as a 50 count blister strip of 20 mg tablets at the link in the "code" box below:

https://basicstero.ws/pct/farestos-pills-20mg

Toremifene Information:

Toremifene Description (credit: Llewellyn, William. “ANABOLICS” 11th ed. 2017.):
Toremifene citrate is an anti-estrogenic drug, specifically classified as a Selective Estrogen-Receptor Modulator (SERM) with mixed agonist and antagonist properties. It is a non-steroidal triphenylethylene derivative, similar in structure and action to both Nolvadex (tamoxifen citrate) and Clomid (clomiphene citrate). Toremifene citrate is used for the treatment of breast cancer in postmenopausal women with estrogen-receptor positive or estrogen-receptor unknown (unsure if the cancer is estrogen responsive) tumors. It works by attaching to the estrogen receptor in various tissues in a competitive manner, blocking endogenous estrogen from exerting biological activity. As an anti-estrogen in many tissues, male bodybuilders and athletes may use toremifene citrate to counter some of the side effects associated with the use of aromatizable or estrogenic anabolic/androgenic steroids. This may include gynecomastia, body fat gain, and increased water retention.

The triphenylethylene compounds (toremifene citrate, tamoxifen citrate, clomiphene citrate) tend to be somewhat intrinsically estrogenic in the liver. This means that while they can block estrogenic activity in some areas of the body, they can actually act as estrogens in this other key area. Estrogenic action in the liver is important in the regulation of serum cholesterol (it tends to support HDL synthesis and LDL reductions). Since steroid-using bodybuilders are already dealing with the negative cardiovascular effects of these drugs, compounding the issue with aromatase inhibitors (which will lower total serum estrogen levels) may not always be the best option. Using a drug that blocks gynecomastia, for example, while at the same time supporting improved cholesterol values, might be much more ideal. In terms of which triphenylethylene agent is most effective in this regard, evidence suggests that the positive lipid altering benefits of toremifene are significantly stronger than those of tamoxifen, a drug normally favored for this purpose. Toremifene citrate may, therefore, be the preferred antiestrogen among those concerned about their lipid profiles.

History (credit: Llewellyn, William. “ANABOLICS” 11th ed. 2017.):
Toremifene citrate was approved by the FDA as a prescription drug in 1997. It is sold in the U.S. under the Fareston brand name, which is made by GTx, Inc. Fareston is also available in over two dozen other countries including Australia, Austria, Belgium, Czech Republic, Finland, France, Germany, Greece, Hungary, Ireland, Italy, Mexico, Netherlands, New Zealand, Portugal, Russia, South Africa, Spain, Sweden, Switzerland, Thailand, Turkey, and the United Kingdom.

Structural Characteristics (credit: Llewellyn, William. “ANABOLICS” 11th ed. 2017.):
Toremifene citrate is classified as a selective estrogen receptor modulator, with both agonist and antagonist properties. It has the chemical designation 2-{p-[(Z)-4-chloro-1,2-diphenyl-1-butenyl]phenoxy}-N,N-dimethylethylamine citrate (1:1).

Side Effects (credit: Llewellyn, William. “ANABOLICS” 11th ed. 2017.):
Toremifene citrate appears to be well tolerated, with a low incidence of serious side effects. In clinical trials, common side effects associated with its use included hot flashes (35%), sweating (20%), elevated liver enzymes (19%), nausea (14%), vaginal discharge (13%), dizziness (95%), edema (5%), vomiting (4%), and vaginal bleeding (2%). Other observed rare adverse events that may or may not be linked to toremifene citrate administration include low white blood cell and platelet counts, skin discoloration or dermatitis, constipation, difficulty breathing, partial motor paralysis, tremor, vertigo, itching, anorexia, visual disturbances, loss of strength, hair loss, depression, jaundice, and rigors (stiffening of the muscles). Antiestrogens may harm the developing fetus and should never be used during pregnancy.

Administration (credit: Llewellyn, William. “ANABOLICS” 11th ed. 2017.):
Toremifene citrate is FDA approved for the treatment of metastatic breast cancer in postmenopausal women with estrogen-receptor positive or unknown tumors. The recommended dose is one 60 mg tablet administered once per day. When used (off-label) to mitigate the estrogenic side effects of anabolic/androgenic steroid use, male athletes and bodybuilders may use 30 mg to 60 mg per day during steroid treatment.

Availability (credit: Llewellyn, William. “ANABOLICS” 11th ed. 2017.):
Toremifene citrate is widely available under the Fareston brand name. It is not commonly sold on the black market, nor is it a high-profile item for counterfeiters.

 

[RThoads]

Addendum: structural considerations and an explanation of toremifene’s decreased carcinogenicity.

Why is Tamoxifen Carcinogenic? What Makes Toremifene Less Toxic?

Most of these compounds may lead to long-term toxic effects. For instance, tamoxifen induces liver cancer in rats after prolonged administration, which has been attributed to the generation of DNA-alkylating species from the metabolism of the stilbene framework. It has been proposed that cytochrome P450 hydroxylates tamoxifen at the allylic position of the ethyl side chain, leading to an alcohol, which can generate a highly delocalized allylic cation 3.6 and therefore alkylate DNA to give product 3.7 through an SN1 mechanism (Fig. 3.6 below).
(Reference: Triphenylethylene - an overview | ScienceDirect Topics)

This proposal also explains the lack of carcinogenicity of toremifene, which can be attributed to destabilization of the positive charge in 3.8 by the inductive effect of the chlorine substituent at the position adjacent to the allylic carbon (Fig. 3.7 below).
(Reference: Triphenylethylene - an overview | ScienceDirect Topics)

Toremifene (Fareston) – A More Modern SERM – is Available in the Basicstero Store

Toremifene Citrate is a selective estrogen receptor modulator (SERM) derived from triphenylethylene. It was patented and approved in Europe in the mid 1990's to treat metastatic ER+ breast cancer in postmenopausal women. Toremifene (Fareston) is an analogue of Tamoxifen and Clomid which can be used to replace these older compounds.

In bodybuilding toremifene citrate is used by men as a drug for post-cycle therapy (PCT) to counteract and/or block some of the effects of excessive estradiol in the body as a result of aromatization of various androgens used. In particular, toremifene is used to restore levels of endogenous testosterone in blood as well as to prevent the estrogen-related side effect of gynecomastia.
In its chemical structure toremifene is very similar to tamoxifen and clomiphene. However, toremifene is a new generation drug and has less toxic side effects than tamoxifen.

For a more effective boost in testosterone production toremifene dosage should be in the range of up to 120 mg per day. This dose can be maintained for a first week of PCT; then, 100mg/day for the second week of PCT; and, finally 60mg/day for the remaining 3 – 4 weeks of PCT. Of course, exact dosages should be determined individually based on blood work results.

This innovative SERM is currently available as a 50 count blister strip of 20 mg tablets at the link in the "code" box below:

https://basicstero.ws/pct/farestos-pills-20mg

Toremifene Information:

Toremifene Description (credit: Llewellyn, William. “ANABOLICS” 11th ed. 2017.):
Toremifene citrate is an anti-estrogenic drug, specifically classified as a Selective Estrogen-Receptor Modulator (SERM) with mixed agonist and antagonist properties. It is a non-steroidal triphenylethylene derivative, similar in structure and action to both Nolvadex (tamoxifen citrate) and Clomid (clomiphene citrate). Toremifene citrate is used for the treatment of breast cancer in postmenopausal women with estrogen-receptor positive or estrogen-receptor unknown (unsure if the cancer is estrogen responsive) tumors. It works by attaching to the estrogen receptor in various tissues in a competitive manner, blocking endogenous estrogen from exerting biological activity. As an anti-estrogen in many tissues, male bodybuilders and athletes may use toremifene citrate to counter some of the side effects associated with the use of aromatizable or estrogenic anabolic/androgenic steroids. This may include gynecomastia, body fat gain, and increased water retention.

The triphenylethylene compounds (toremifene citrate, tamoxifen citrate, clomiphene citrate) tend to be somewhat intrinsically estrogenic in the liver. This means that while they can block estrogenic activity in some areas of the body, they can actually act as estrogens in this other key area. Estrogenic action in the liver is important in the regulation of serum cholesterol (it tends to support HDL synthesis and LDL reductions). Since steroid-using bodybuilders are already dealing with the negative cardiovascular effects of these drugs, compounding the issue with aromatase inhibitors (which will lower total serum estrogen levels) may not always be the best option. Using a drug that blocks gynecomastia, for example, while at the same time supporting improved cholesterol values, might be much more ideal. In terms of which triphenylethylene agent is most effective in this regard, evidence suggests that the positive lipid altering benefits of toremifene are significantly stronger than those of tamoxifen, a drug normally favored for this purpose. Toremifene citrate may, therefore, be the preferred antiestrogen among those concerned about their lipid profiles.

History (credit: Llewellyn, William. “ANABOLICS” 11th ed. 2017.):
Toremifene citrate was approved by the FDA as a prescription drug in 1997. It is sold in the U.S. under the Fareston brand name, which is made by GTx, Inc. Fareston is also available in over two dozen other countries including Australia, Austria, Belgium, Czech Republic, Finland, France, Germany, Greece, Hungary, Ireland, Italy, Mexico, Netherlands, New Zealand, Portugal, Russia, South Africa, Spain, Sweden, Switzerland, Thailand, Turkey, and the United Kingdom.

Structural Characteristics (credit: Llewellyn, William. “ANABOLICS” 11th ed. 2017.):
Toremifene citrate is classified as a selective estrogen receptor modulator, with both agonist and antagonist properties. It has the chemical designation 2-{p-[(Z)-4-chloro-1,2-diphenyl-1-butenyl]phenoxy}-N,N-dimethylethylamine citrate (1:1).

Side Effects (credit: Llewellyn, William. “ANABOLICS” 11th ed. 2017.):
Toremifene citrate appears to be well tolerated, with a low incidence of serious side effects. In clinical trials, common side effects associated with its use included hot flashes (35%), sweating (20%), elevated liver enzymes (19%), nausea (14%), vaginal discharge (13%), dizziness (95%), edema (5%), vomiting (4%), and vaginal bleeding (2%). Other observed rare adverse events that may or may not be linked to toremifene citrate administration include low white blood cell and platelet counts, skin discoloration or dermatitis, constipation, difficulty breathing, partial motor paralysis, tremor, vertigo, itching, anorexia, visual disturbances, loss of strength, hair loss, depression, jaundice, and rigors (stiffening of the muscles). Antiestrogens may harm the developing fetus and should never be used during pregnancy.

Administration (credit: Llewellyn, William. “ANABOLICS” 11th ed. 2017.):
Toremifene citrate is FDA approved for the treatment of metastatic breast cancer in postmenopausal women with estrogen-receptor positive or unknown tumors. The recommended dose is one 60 mg tablet administered once per day. When used (off-label) to mitigate the estrogenic side effects of anabolic/androgenic steroid use, male athletes and bodybuilders may use 30 mg to 60 mg per day during steroid treatment.

Availability (credit: Llewellyn, William. “ANABOLICS” 11th ed. 2017.):
Toremifene citrate is widely available under the Fareston brand name. It is not commonly sold on the black market, nor is it a high-profile item for counterfeiters.

 

[edjohn88]

Well I just got a package in and nothing is marked correct so i have no idea whats what. My order was 2 injectable anadrol, 2 test cyp, and 5 test suspension…

 

[RThoads]

@edjohn88 if you need any help figuring out what each are, send me a private message.
And, yes, the suspension will be opaque because it is not a solution. Suspension is very fine solid particle just floating in water, NOT a dissolved solution. So it sound like the 5 white ones are your suspension.

 

[broilovesushi]

Well I just got a package in and nothing is marked correct so i have no idea whats what. My order was 2 injectable anadrol, 2 test cyp, and 5 test suspension…

Damn what you need all that test suspension for? I’m assuming pre workout?

 

[RThoads]

Damn what you need all that test suspension for? I’m assuming pre workout?

I never used suspensions myself. I always wonder what guys do with it.
There is Test-base in oil (solution) that I think would be easier to use than a suspension (product I'm talking about is linked to in "code" box below).

https://basicstero.ws/testosterones/pharmatest-100-oil-base

What is special about the water suspension that makes guys prefer it over a Test-base in oil?

 

[edjohn88]

Damn what you need all that test suspension for? I’m assuming pre workout?

Oh they had a bonus or something I just bought 2. So far I've felt nothing from it at 25mg. Next time I'll try 50mg.

 

[Pharmacom Support]

Well I just got a package in and nothing is marked correct so i have no idea whats what. My order was 2 injectable anadrol, 2 test cyp, and 5 test suspension…

Hi, you can contact the store support team, on our website, through the message section, they will tell you how to distinguish between products in discreet shipping.