Pharmasource EU pharmaceuticals

It's really intresting and weird. But even my pharmacist told me to use brand name drugs rather than generics ( he got more profit from generics) because brand name works 100% on all of people but generics dosent works on all of people

this is pure bullshit! 20 mg of cialis, are 20 mg of cialis, whether it is generic or branded. the powders are all from China! whether the drug is branded, generic or ugl. only the excipients can change, but these do not affect the effectiveness of the drug. Your pharmacist is a goat.

I tried Cialis Lilly from my local pharmacy, and cialis balkan (esculap) no differences on performance and same side effects. with both I had a headache and a feeling of exhaustion the next day. with Viagra I have far fewer problems, so from some years I only use Viagra.
 
this is pure bullshit! 20 mg of cialis, are 20 mg of cialis, whether it is generic or branded. the powders are all from China! whether the drug is branded, generic or ugl. only the excipients can change, but these do not affect the effectiveness of the drug. Your pharmacist is a goat.

I tried Cialis Lilly from my local pharmacy, and cialis balkan (esculap) no differences on performance and same side effects. with both I had a headache and a feeling of exhaustion the next day. with Viagra I have far fewer problems, so from some years I only use Viagra.
Yeah I haven't notice a difference either on various med. Anyway most pharmacist if not all they always recomened brand name rather than generics
 
It's not about what pharmacists recommend but the biochemical or pharmaceutical (not financial) reasons why exactly that we wonder about.
 
For those interested, here is the technical reason for the differences between generic and brand name drugs.

Long story short... the chemical structure is the same. It's the exact same drug. However, the added fillers and such can create a difference in rates of absorption.

In the bloodwork, the levels of the drug in your system will be biologically equivalent, however, they may not be therapeutically equivalent due to the different rate of absorption.

upload_2019-6-15_12-9-30.png

Looking at this example above as already analyzed by the FDA... you can see that the generic version of Wellbutrin, Budeprion, has a similar area under the curve. The FDA has deemed this biologically equivalent and the 300mg generic drug was placed on the market. However, after usage on the market and many complaints of not being effective, it was determined to not be therapeutically equivalent in a later study done by the FDA to confirm the validity of the complaints. Looking at the curve, you can see why it may not be therapeutically equivalent, despite being biologically equivalent and an equivalent dose of 150mg of each.

~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
"Citing difficulty recruiting subjects, the company never performed the tests. Then in 2010, the FDA took the unusual step of conducting its own independent trial of 24 subjects. It found that the maximum concentration of Budeprion XL 300 in the blood plasma reached only 75 percent of the amount Wellbutrin XL 300 released, and, in some volunteers, the level never reach 40%. This discrepancy in dosage could render the drug less effective in treating depression and could explain the side effects we were hearing about, Graedon said.

When results of the trials became available in 2012, FDA allowed the products to remain approved but reclassified them as not equivalent to Wellbutrin XL 300. However, the FDA sent both Teva and Impax communications asking them to voluntarily withdraw the drug from the market. Both companies complied with the request. It is unclear if any other national markets demanded a withdrawal of these products."
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Tricky subject we have here with PS because the core compound, tadalafil, will be exactly the same as name brand Cialis... however, the fillers and such added could create a different rate of absorption which create a different therapeutic effect.

Essentially, PS is not cheating anyone on the cialis or doing anything wrong. The compound is just not matching the absorption rate as name brand Cialis. You are still getting the correct amount of drug that you purchased, which his lab reports confirm.

I hope this helps you guys understand...

If anyone would like to read further into this, attached is a reference.
 

Attachments

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Hopefully, people understand that the differences between extended release products might be extremely pronounced compared to products, in which the rate of release is not intentionally modified.
 
this is pure bullshit! 20 mg of cialis, are 20 mg of cialis, whether it is generic or branded. the powders are all from China! whether the drug is branded, generic or ugl. only the excipients can change, but these do not affect the effectiveness of the drug. Your pharmacist is a goat.

I tried Cialis Lilly from my local pharmacy, and cialis balkan (esculap) no differences on performance and same side effects. with both I had a headache and a feeling of exhaustion the next day. with Viagra I have far fewer problems, so from some years I only use Viagra.

Note true.
 
As a pharmacist myself, some excipients in some generics definitely alter the response to a treatment.

Using an N=1 example on something like cialis which I’ve never heard not working (generic or princeps) isn’t going to discredit the pharmacist.

Big issue in Europe rn regarding levothyrox (synthroid) and its generics.

Drug specific, excipient specific, patient specific... never assume everyone is the same
 
For those interested, here is the technical reason for the differences between generic and brand name drugs.

Long story short... the chemical structure is the same. It's the exact same drug. However, the added fillers and such can create a difference in rates of absorption.

In the bloodwork, the levels of the drug in your system will be biologically equivalent, however, they may not be therapeutically equivalent due to the different rate of absorption.

View attachment 113847

Looking at this example above as already analyzed by the FDA... you can see that the generic version of Wellbutrin, Budeprion, has a similar area under the curve. The FDA has deemed this biologically equivalent and the 300mg generic drug was placed on the market. However, after usage on the market and many complaints of not being effective, it was determined to not be therapeutically equivalent in a later study done by the FDA to confirm the validity of the complaints. Looking at the curve, you can see why it may not be therapeutically equivalent, despite being biologically equivalent and an equivalent dose of 150mg of each.

~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
"Citing difficulty recruiting subjects, the company never performed the tests. Then in 2010, the FDA took the unusual step of conducting its own independent trial of 24 subjects. It found that the maximum concentration of Budeprion XL 300 in the blood plasma reached only 75 percent of the amount Wellbutrin XL 300 released, and, in some volunteers, the level never reach 40%. This discrepancy in dosage could render the drug less effective in treating depression and could explain the side effects we were hearing about, Graedon said.

When results of the trials became available in 2012, FDA allowed the products to remain approved but reclassified them as not equivalent to Wellbutrin XL 300. However, the FDA sent both Teva and Impax communications asking them to voluntarily withdraw the drug from the market. Both companies complied with the request. It is unclear if any other national markets demanded a withdrawal of these products."
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

Tricky subject we have here with PS because the core compound, tadalafil, will be exactly the same as name brand Cialis... however, the fillers and such added could create a different rate of absorption which create a different therapeutic effect.

Essentially, PS is not cheating anyone on the cialis or doing anything wrong. The compound is just not matching the absorption rate as name brand Cialis. You are still getting the correct amount of drug that you purchased, which his lab reports confirm.

I hope this helps you guys understand...

If anyone would like to read further into this, attached is a reference.

Thanks for posting this.

I have been on script opioids every day for going on 26 years now. Your post is 100% correct strictly based on my personal empirical experience. I was early 20s when I started using opioids and after being on them just a few months one day after a refill without even looking at the bottle I called the pharmacist to tell her she gave me the wrong pills. She said no I didn't by why do you say that; I replied; these aren't working like they have in the past. She said; Oh this is the first time I gave you generic instead of brand name. Going forward its always been the same game; both effectiveness and side effects varies not only between name brand and generic but btw generic manufacturers as well. Some are great some decent some just ineffective with additional side effects - With brand name always being superior. If one drug by a particular pharma manufacturer is crap it doesn's mean all drugs by that pharma is crap it just depends on the carrier agents and binding agents used in each drug which determines how effective it works despite all having the same active ingredients. In the study you post it mentions Teva which make a narcotic patch it is crap supposed to last 7 days many people only get 2-5 days out of it including myself 36 hours then it is spent. Try to get insurance to cover name brand - they do but wack me a 200$ "penalty" for not using the generic which doesn't work and Teva is the only generic every pharmacy around me carries. I blame this on the corruption btw big pharma and the FDA whose sole purpose is to protect big pharma profits by allowing inferior products on the market. These drug discrepancies are well known in the chronic pain community.
 
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Good morning all.

Any feedback on a combo Testo mix 300 + Primo 200 from this source?

I consider starting this stack with 3 inj/week with 250 of testo mix + 270 primo/inj.

The price of the testo mix is so low I cant believe it's true.
 
Good morning all.

Any feedback on a combo Testo mix 300 + Primo 200 from this source?

I consider starting this stack with 3 inj/week with 250 of testo mix + 270 primo/inj.

The price of the testo mix is so low I cant believe it's true.
I had bad pip with test e 350 I assume won't he much different cause it has prop in it etc. Maybe I'm wrong you should try it I haven't had any problems with other testosterone from PS all legit and smooth
 
I just want to review the Pip of his DHB. Injected 1ml DHB subQ to get a feel of what I'm dealing with since all those horror stories say DHB is brutal. Day 3 (Today) and the pain has been the same since injected. Nothing crippling, just sore when touched like a normal subQ shot. Day 2 I injected 3ml DHB into my right glute and it was pretty sore for the first day. Now on the second day (Today) the pain is pretty much gone.
 
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