Primo:

[strangegenericguy]

i did most of my cycle at higher doses of primo, and found that 1.33 primo/test ratio is the sweet spot for me. with 250mg HCG daily i was able to take it even higher at over 2.1x test. adding mast hasn’t affected me negatively , ie i didn’t have to lower primo once i added mast into the mix. seems to just work independently


the one takeaway is that test gives me the most sides and my ideal test dose is lower than most guys would run. (200-300 on cycle and then stack non test on top )

Thanks for the answer!

 

[y777]

Thanks for the answer!

one thing to add to my original post. i started taking telmisartan , 40mg first week the. 80mg daily since. it took down my hematocrit from 53 to 42 in about a month.

 

[Millard]

I am fairly certain actually Primo doesnt effect lipids

This is not correct. Primo will have no effect on kidneys, liver, or Lipids. The study done on women at 1200mg EW proved this with no adverse health effects.

Anavar however may alter the lipid profile.

You can't make those conclusions from the study you are referencing. The authors certainly don't:

"The dose of methenolone enanthate (1200 mg per week) was massive and, since it is a long-acting compound, an enormous dose level should accumulate. The effect of the administration of huge amounts of potent androgenic hormones has not been evaluated completely."

The study is called “Effect of Methenolone Enanthate in Advanced Cancer of the Breast.”

Kennedy, B.J. and Yarbro, J.W. (1968), Effect of methenolone enanthate (NSC-64967) in advanced cancer of the breast. Cancer, 21: 197-201. https://doi.org/10.1002/1097-0142(196802)21:2<197::AID-CNCR2820210207>3.0.CO;2-R

Abstract
Methenolone enanthate, a synthetic long-acting anabolic steroid, was evaluated by a randomized study in the treatment of advanced carcinoma of the breast in postmenopausal women following the protocol established by the Cooperative Breast Cancer Group. Of 27 patients receiving methenolone enanthate, (48%) had objective improvement. There were no improvements in 13 patients receiving testosterone propionate. The median duration of therapy and the median period of survival from the onset of hormone therapy to death or present living time was greater for the responders to methenolone enanthate than the nonresponders. The unusual high incidence of regression from methenolone enanthate therapy may be due to the massive dose employed, a defect in the method of study being employed in clinical trials, a difference that could occur by chance alone or a difference in the biological nature of the disease in the two groups. Since the difference may indicate that methenolene enanthate is an effective hormone, further studies are warranted.

 

[Millard]

Cardiac and Metabolic Effects of Anabolic-Androgenic Steroid Abuse on Lipids, Blood Pressure, Left Ventricular Dimensions, and Rhythm - PMC

Recent surveys and reports suggest that many athletes and bodybuilders abuse anabolic-androgenic steroids (AAS). However, scientific data on the cardiac and metabolic complications of AAS abuse are divergent and often conflicting. A total of 49 ...

www.ncbi.nlm.nih.gov

Here is a paper looking at various studies with effects of various steroids, including primo, and includes abnormal plasma lipoproteins. Unfortunately, the original papers cited are mostly behind paywalls, so you are going to have to pay $ if you want to read them.

See table 1.

Thanks for this. That is a really useful table!

 

[malfeasance]

Thanks for this. That is a really useful table!

View attachment 269884

"Dickerman et al reported a 20-year-old male bodybuilder who self-administered AAS 700 mg/week and had sudden cardiac arrest. Autopsy indicated LVH with a cardiac mass >2 times the upper limit of normal."

Disturbing stuff. I wonder how long that 20 year old had been at it.

 

[malfeasance]

Ibid: "The patient presented with markedly elevated LDL (596 mg/dl) and depressed HDL (14 mg/dl) yet had no family history of premature atherosclerosis or cardiac events. Within a month of discontinuing AAS, his LDL decreased to 220 mg/dl and his HDL increased to 35 mg/dl." This was a 22 year old. I am quoting this only to show the importance of doing blood tests, and, more importantly, the importance of taking breaks rather than cruising on elevated hormone levels out of fear of losing size.

Note that the improvements still aren't so great, but this break was only for a month. Breaks should probably be quite a bit longer, or at least long enough to allow lipids to normalize and then let your body enjoy the benefits of sitting there with normal lipids for an extended period of time.

 

[poolshockguy]

Ibid: "The patient presented with markedly elevated LDL (596 mg/dl) and depressed HDL (14 mg/dl) yet had no family history of premature atherosclerosis or cardiac events. Within a month of discontinuing AAS, his LDL decreased to 220 mg/dl and his HDL increased to 35 mg/dl." This was a 22 year old. I am quoting this only to show the importance of doing blood tests, and, more importantly, the importance of taking breaks rather than cruising on elevated hormone levels out of fear of losing size.

Note that the improvements still aren't so great, but this break was only for a month. Breaks should probably be quite a bit longer, or at least long enough to allow lipids to normalize and then let your body enjoy the benefits of sitting there with normal lipids for an extended period of time.

Is this regarding primo? Does it harm HDL and LDL ?

 

[malfeasance]

Is this regarding primo? Does it harm HDL and LDL ?

No, just steroids in general. Here is that bodybuilder's case study.

46. McNutt RA, Ferenchick GS, Kirlin PC, Hamlin NJ. Acute myocardial infarction in a 22-year-old world class weight lifter using anabolic steroids. Am J Cardiol. 1988;62:164. [PubMed] [Google Scholar]

It does not appear to be accessible without paying for it.

 

[MindlessWork]

Dylan G, as in... "Dylan Gemelli" ? Are you on any of his forums or ever were in the past?

Umm, regarding your hair, or any steroid side effect, a difference of 200mg is a big difference... Would def start lower than higher.

Who trusts what that tweaker Dylan Gemelli thinks? He's pretty clueless on a lot of things.