Show me a study for year round tren usage? That is some of the most mentally mind altering shit when on. I don't care what your estrogen levels are at.I'm aware of that study. The neurodegeneration in rats only occurred when they didn't have sufficient estrogen. AKA when they gave the rats Tren with no Test. I never crash my estrogen and I don't use AI'S. I keep my test at TRT levels and add other compounds. Also, I take supplements that help heal the brain and prevent Alzheimers/Dementia. Tren is life