Qingdao Sigma Chemical Co., Ltd (International, US, EU, Canada and Australia domestic

The number of times someone says "it's common knowledge" and what they're saying is horseshit is really high.

Test Cyp and Test E were both being administered both IM and Subq from the moment they were introduced in the 50's. Oils werent "designed to be deep in the muscle", good grief.

The pushback against anyone wanting to run their gear SubQ in this thread is just bonkers.
Then why does it say it on every injectable medication I buy? My RX deca, UGL testosterone, even water based birth control shots say for intramuscular use only?

Do whatever you want but stop pretending subq has been mainstream for 70 years. If the drug maker says use intramuscular, They designed it to be used that way and intend for it to be used that way.
 
I know you might be joking but it's true. Keeps your immune system strong. Every couple of months I'll finger my girlfriends ass and "accidentally" forget to wash my hands. I'll touch every door knob and remote in my house.

Don't confuse laziness with keeping your immune system strong though
That's my kind of disease prevention
 
I know you might be joking but it's true. Keeps your immune system strong. Every couple of months I'll finger my girlfriends ass and "accidentally" forget to wash my hands. I'll touch every door knob and remote in my house.

Don't confuse laziness with keeping your immune system strong though
Damn what a coincidence, every week I finger your girls ass & do the same
 
Then why does it say it on every injectable medication I buy? My RX deca, UGL testosterone, even water based birth control shots say for intramuscular use only?

Do whatever you want but stop pretending subq has been mainstream for 70 years. If the drug maker says use intramuscular, They designed it to be used that way and intend for it to be used that way.
It’s because that dude is full of shit. If it’s oil based, it is not meant to go subq. It’s for IM.
 
The number of times someone says "it's common knowledge" and what they're saying is horseshit is really high.

Test Cyp and Test E were both being administered both IM and Subq from the moment they were introduced in the 50's. Oils werent "designed to be deep in the muscle", good grief.

The pushback against anyone wanting to run their gear SubQ in this thread is just bonkers.

Care to post some literature?

All of the research development for injecting steroids has been focused on injecting less and less frequently. This is done by a pocket of oil being deposited in the muscle where it slowly releases over time. Injecting subq is the opposite of that. There’s certainly no research being done on how to make injections MORE frequent. Fringe TRT clinics don’t count as literature.
 
It’s because that dude is full of shit. If it’s oil based, it is not meant to go subq. It’s for IM.
I say just let him figure it out the hard way. When he gets an abscess from his oil based injection taking 3 weeks to absorb, While he continues to add more oil every 3 days...he'll learn something.

Some people you just have to sit back and let them put their hand on the stove. They don't learn any other way.
 
I know you might be joking but it's true. Keeps your immune system strong. Every couple of months I'll finger my girlfriends ass and "accidentally" forget to wash my hands. I'll touch every door knob and remote in my house.

Don't confuse laziness with keeping your immune system strong though
Just eat the ass
 
That's how you get pink eye
I never got pink eye from it lol but I do get a little sketched out when eating the pussy doggystyle or 69 and the asshole be on your nose right next to your eye lol. I'd be more likely to get pink eye from the remote after fingering the ass because I'd forget and itch my eye haha
 
I know you might be joking but it's true. Keeps your immune system strong. Every couple of months I'll finger my girlfriends ass and "accidentally" forget to wash my hands. I'll touch every door knob and remote in my house.

Don't confuse laziness with keeping your immune system strong though
While you're at it, don't confuse an obsession with ass play as the norm for a hetero man when it very well could be your true closeted self screaming "Guys! Wait for me!"

When I read guys in mental anguish asking for help because their libido is in the can I don't go off half cocked suggesting prostitutes or EDdrugs. They are searching for the magic elixir that will cure them and bring back the lust and long nights they believe they are missing out on. They blame it on hormones and long hours at the office.

I've suggested a relaxing evening with the "other" kind of porn on several occasions over the years. I don't suggest it in every case. But the ones I do, and who believed themselves to be 100% straight(so they claim), I have close to a 75% rate of being correct. You didn't ask for help so I won't suggest anything one way or the other. I will say I won't be surprised if the seed was planted. Buckle up Nuvo6, this could be the first day of the rest of your life.
 
While you're at it, don't confuse an obsession with ass play as the norm for a hetero man when it very well could be your true closeted self screaming "Guys! Wait for me!"

When I read guys in mental anguish asking for help because their libido is in the can I don't go off half cocked suggesting prostitutes or EDdrugs. They are searching for the magic elixir that will cure them and bring back the lust and long nights they believe they are missing out on. They blame it on hormones and long hours at the office.

I've suggested a relaxing evening with the "other" kind of porn on several occasions over the years. I don't suggest it in every case. But the ones I do, and who believed themselves to be 100% straight(so they claim), I have close to a 75% rate of being correct. You didn't ask for help so I won't suggest anything one way or the other. I will say I won't be surprised if the seed was planted. Buckle up Nuvo6, this could be the first day of the rest of your life.
I sounds like you think and fantasize about this quite often. I'm sorry you feel such shame for wanting to engage in anal sex with a female. Perhaps that's something that can be addressed with therapy. It's 2023, you don't need to hide your desires.
 
Care to post some literature?

All of the research development for injecting steroids has been focused on injecting less and less frequently. This is done by a pocket of oil being deposited in the muscle where it slowly releases over time. Injecting subq is the opposite of that. There’s certainly no research being done on how to make injections MORE frequent. Fringe TRT clinics don’t count as literature.
Wait, I can't just say "It's common knowledge"? :)

Anyway, no I'm not basing that off of what "fringe TRT clinics" say. There's actually quite a bit of literature on this, particularly recently (and I'm not just talking about all of the recent literature studying it for replacement therapy):


Per your assertion that "subq is the opposite of that", that's contradicted in virtually all literature I've seen,

As the blood perfusion in the s.c. tissue is lower than in the muscles, a s.c. injection will result in a delayed absorption of the drug with respect to an i.m. injection [17].

Interestingly, while the consensus in this thread is that SubQ is only viable for "TRT amounts", there are numerous references in literature about much larger volumes of oil-based compounds:

S.c. injections are the most-often used parenteral administration route due the possibility of self-injection by the patients, but the administered volume is limited. The administration of volumes larger than 1.5 to 2 mL usually requires multiple injections to minimize the risk of considerably high pain upon injection.

I've never gone higher, but I've personally had no issues running up to 1.1ml per injection.

wrt my assertion that oil-based on compounds weren't necessarily designed for IM per se, when Test Prop was introduced it was used exclusively IM, but with the introduction of Test Cyp and Test E in the late 1950s.

Primary sources for this are buried in very old literature I haven't seen in ages, but plenty of references exist for this in recent literature.


That last study has a pretty neat infographic showing the timeline of various testosterone formulations from 1889 to present.

Interestingly, while Test Prop (and later) Test Undecanoate were designed for IM injection, Test Cyp and Test E were used both IM and SubQ from the beginning.

IM was certainly more popular in the beginning, but the decision was never based on "these are designed for IM and aren't designed for SubQ".

Regardless, the is study after study coming out proving the viability of SubQ injections, I'm not going to dig up/post all of the links but from the references at the above links you could pull a dozen+ easily.

FWIW, there's some evidence that SubQ may be preferable for athletes, because the distribution of depot-based injections is heavily influenced by lymphatic drainage. In SubQ tissue, this is relatively stable, but is increased by physical activity IM:

Therefore, the pharmacokinetics of testosterone esters administered via IM vs SC route will vary according to the lymphatic circulation of the tissue. Lymphatic drainage is dependent on intrinsic and extrinsic pumping. Intrinsic pumping is dependent on the contraction of lymphangions (muscular unit of the lymphatics with unidirectional valves) that transport lymph by mechanisms analogous to that occurring in the cardiac chambers (42). Extrinsic pumping results from intermittent external pressure exerted by skeletal muscle contractions on the lymphatics (42). As the lymphatic drainage from SC tissue is largely dependent on intrinsic pumping, while IM lymphatic flow is also substantially influenced by extrinsic pumping during physical activity (43), these drainage patterns suggest that testosterone esters administered SC likely have more stable absorption kinetics compared to IM administration.

IMO the science is quite clear that SubQ injections are very viable, but for whatever reason bodybuilders are some of the worst I've seen about getting irrationally angry at anything evolving or changing. This is definitely one of those situations.
 
Wait, I can't just say "It's common knowledge"? :)

Anyway, no I'm not basing that off of what "fringe TRT clinics" say. There's actually quite a bit of literature on this, particularly recently (and I'm not just talking about all of the recent literature studying it for replacement therapy):


Per your assertion that "subq is the opposite of that", that's contradicted in virtually all literature I've seen,

As the blood perfusion in the s.c. tissue is lower than in the muscles, a s.c. injection will result in a delayed absorption of the drug with respect to an i.m. injection [17].

Interestingly, while the consensus in this thread is that SubQ is only viable for "TRT amounts", there are numerous references in literature about much larger volumes of oil-based compounds:

S.c. injections are the most-often used parenteral administration route due the possibility of self-injection by the patients, but the administered volume is limited. The administration of volumes larger than 1.5 to 2 mL usually requires multiple injections to minimize the risk of considerably high pain upon injection.

I've never gone higher, but I've personally had no issues running up to 1.1ml per injection.

wrt my assertion that oil-based on compounds weren't necessarily designed for IM per se, when Test Prop was introduced it was used exclusively IM, but with the introduction of Test Cyp and Test E in the late 1950s.

Primary sources for this are buried in very old literature I haven't seen in ages, but plenty of references exist for this in recent literature.


That last study has a pretty neat infographic showing the timeline of various testosterone formulations from 1889 to present.

Interestingly, while Test Prop (and later) Test Undecanoate were designed for IM injection, Test Cyp and Test E were used both IM and SubQ from the beginning.

IM was certainly more popular in the beginning, but the decision was never based on "these are designed for IM and aren't designed for SubQ".

Regardless, the is study after study coming out proving the viability of SubQ injections, I'm not going to dig up/post all of the links but from the references at the above links you could pull a dozen+ easily.

FWIW, there's some evidence that SubQ may be preferable for athletes, because the distribution of depot-based injections is heavily influenced by lymphatic drainage. In SubQ tissue, this is relatively stable, but is increased by physical activity IM:

Therefore, the pharmacokinetics of testosterone esters administered via IM vs SC route will vary according to the lymphatic circulation of the tissue. Lymphatic drainage is dependent on intrinsic and extrinsic pumping. Intrinsic pumping is dependent on the contraction of lymphangions (muscular unit of the lymphatics with unidirectional valves) that transport lymph by mechanisms analogous to that occurring in the cardiac chambers (42). Extrinsic pumping results from intermittent external pressure exerted by skeletal muscle contractions on the lymphatics (42). As the lymphatic drainage from SC tissue is largely dependent on intrinsic pumping, while IM lymphatic flow is also substantially influenced by extrinsic pumping during physical activity (43), these drainage patterns suggest that testosterone esters administered SC likely have more stable absorption kinetics compared to IM administration.

IMO the science is quite clear that SubQ injections are very viable, but for whatever reason bodybuilders are some of the worst I've seen about getting irrationally angry at anything evolving or changing. This is definitely one of those situations.
Just go IM it's better
 
I only dropped in to see what the verdict was on these guys gear since there prices are ridiculously good, but since im here il give my 2 cents.

DONT INJECT OIL SUBQ!!!!

I went down the same path a few years ago thinking oh absorption rates are slower in fat so my levels will stay more stable as its absorbing slower.. NO!

IT ABSORBS THAT SLOW YOU WILL HAVE LITTLE SORE BUMPS OF OIL ALL OVER YOUR FUCKING BODY FOR MONTHS AND MONTHS.

So yeah just dont do it, unless you like risking infection and wasting gear.

Ps. Has anyone had testing done on these guys primo e? Whats the verdict?
 
I only dropped in to see what the verdict was on these guys gear since there prices are ridiculously good, but since im here il give my 2 cents.

DONT INJECT OIL SUBQ!!!!

I went down the same path a few years ago thinking oh absorption rates are slower in fat so my levels will stay more stable as its absorbing slower.. NO!

IT ABSORBS THAT SLOW YOU WILL HAVE LITTLE SORE BUMPS OF OIL ALL OVER YOUR FUCKING BODY FOR MONTHS AND MONTHS.

So yeah just dont do it, unless you like risking infection and wasting gear.

Ps. Has anyone had testing done on these guys primo e? Whats the verdict?
Thread 'QSC Primo testing results'
QSC Primo testing results
 
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