Ghoul
Well-known Member
I’ve been using QSC tirz because my ineurence
Won’t cover it but they do cover ozempic. I also have Q’s sema.
I’ve been stockpiling unused pens in the fridge figuring it will last longer than UGL un-constituted. I do the same with insulin, I am still getting my doc to rx me old dosages I had pre-GLP use.
What I’ve been doing dosage wise is using my RX ozempic plus initially 5mg tirz then 10 for
Appetite suppression (I get none w ozempic 1mg and endo won’t rx me more cuz im not obese and my a1c is fine now )
I did an experiment and bumped tirz to 15 mg
Single shot. Ditched ozempic. Phenomenal glucose and insulin control. Didn’t need any Humalog thru the day. Just Lantus. But day 4 , the half life point , it all goes to sh*t. I had to start using insulin again. So either I split up the 15 to biweekly (and lose some suppression ) or stack back some sema.
The two drugs both have pros and cons. As someone with T2D who uses slin and wears a cgm my main takeaways are:
Sema (using ozempic )
- much better at slowing gastric emptying. My glucose peaks aren’t as high as with tirz and eating mos foods won’t hit my glucose readings until almost two hours later. Only liquids hit asap
- seven day half life IIRC
Tirz (QSC tirz)
- excellent appetite suppression albeit only at highest doses. Not gradual for me at all. Either it’s suppressing or it isn’t and I’m starving
- shorter half life for me means at four day mark I lose efficacy for diabetes control and appetite
This short half life dilemma makes me think of Advil. Say you need 2 pills of 200 mg to clear a headache. Half life is only 4 hours but you get rx that says it’s supposed to last a full day. How do you deal with it ? Taking 200 every 4 hours won’t clear the headache. It might but maybe not with the drug alone. Hence either more dosage via UGL or stacking. And if you do stack do you do 15 tirz every 7 days and the. Days 4-7 you’re riding on sema only or you so 7.5 x2 plus sema to get coverage.
/// apologies for going into detail on the drugs - I am aware there’s a separate thread. Just wanted to hit up the more engaged folks who are running Q compounds.
I don't monitor glucose, as I'm not diabetic (though I want a CGM just to correlate glucose levels with how I'm feeling, to optimize my diet).
But all the rest of your observations regarding Tirz and Sema are spot on.