MESO-Rx
Anabolic Steroids
Qingdao Sigma Chemical Co., Ltd (International, US, EU, Canada and Australia domestic
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Ghoul
Well-known Member
One other datapoint.
Remember you're asking for first hand experience and not usual study and data heavy backed answers I give.
I can't give you certainty or specifics beyond what I've noticed in myself and others. as well as the "observered" evidence of clinicians and self reporters writing online.
We're out on the edge with this topic.
The two times I stopped weakened my response. This wasn't psychosomatic, I wasn't looking for this but realized it in hindsight before I knew it was a possibility.
I *suspect*, a "break" means a full washout, or about 4 weeks. Both of mine were 3-4 months.
As far as "how do you stay on if you don't have diabetes or require weight loss", it seems to me that remaining below whatever your "maintenance dose" is sufficient.
Instead of staying at a dose until your weight drops to the "setting" where appetite suppression stops, drop the dose to that point instead. There's a level where you'll feel nothing. You'll still benefit from enhanced glucose control, insulin sensitivity, reduced systemic inflammation, liver protection, anti-atrial hypertrophy effects.
It's common for a lot of people starting at the lowest "pharma protocol" dose to feel nothing. Even the second or third tiers sometimes feel zero effect on appetite. They're in the same "maintenance dose" phase, one where appetite isn't involved, but all those extra GLP-1s are still agonizing GLP receptors found in nearly every organ.
Remember you're asking for first hand experience and not usual study and data heavy backed answers I give.
I can't give you certainty or specifics beyond what I've noticed in myself and others. as well as the "observered" evidence of clinicians and self reporters writing online.
We're out on the edge with this topic.
The two times I stopped weakened my response. This wasn't psychosomatic, I wasn't looking for this but realized it in hindsight before I knew it was a possibility.
I *suspect*, a "break" means a full washout, or about 4 weeks. Both of mine were 3-4 months.
As far as "how do you stay on if you don't have diabetes or require weight loss", it seems to me that remaining below whatever your "maintenance dose" is sufficient.
Instead of staying at a dose until your weight drops to the "setting" where appetite suppression stops, drop the dose to that point instead. There's a level where you'll feel nothing. You'll still benefit from enhanced glucose control, insulin sensitivity, reduced systemic inflammation, liver protection, anti-atrial hypertrophy effects.
It's common for a lot of people starting at the lowest "pharma protocol" dose to feel nothing. Even the second or third tiers sometimes feel zero effect on appetite. They're in the same "maintenance dose" phase, one where appetite isn't involved, but all those extra GLP-1s are still agonizing GLP receptors found in nearly every organ.
I never said it doesn't work I said the appetite suppression was mostly gone at the same dosages. It was still working for my BG for what I could tell.
That's why for me a good idea is just start using it, ride out the appetite suppression and try to find the lowest dosage where you have no suppression and great BG control and other health benefit, when you wanna cut Increase dosage, when you wanna bulk go back at that precious dosage. End of story
PushPullPl8s
New Member
Hi @Qingdao Sigma Chemicals
Is there a new telegram? I haven't been active and noticed the old one is gone.
Is there a new telegram? I haven't been active and noticed the old one is gone.
So, basically you’re using it all the time, got it.
Not at the moment, but before yes. Now I'm not using it as my coach told me to stop it and I'm following his indications.
We are trying to control BG etc with other things.
But yes if I was to use it I would use it all the time.
Ghoul
Well-known Member
For what it's worth, there are other medications where breaks in treatment result in seroconversion, that is, the immune system developing antibodies to the drug that can make it less effective when treatment is resumed. The strategy to mitigate this risk is to ensure treatment is as continuous as possible. keeping breaks to an absolute minimum.
I have no idea if that's what's going on here, but the dynamic seems similar.
I have no idea if that's what's going on here, but the dynamic seems similar.
Last chance to grab oils at legacy prices before all go up
Gear is so GD cheap I can't imagine people getting too upset over a raise. Not shilling, but I'm pretty sure we all know the value play here.
Ghoul
Well-known Member
Also, the versions of these drugs we get are synthetic, not the recombinant type created by reprogramming yeast genes like pharma does. This makes the peptides we're using look less like the natural hormones they're mimicking and more "alien" to the immune system. So that may make it easier for the immune system to target and remove them from our body, reducing effectiveness.
The synthetic type also has a different set of after manufacturing contaminants than recombinant, and were never put through human trials like the recombinant versions, so there's yet another set of unknowns.
The synthetic type also has a different set of after manufacturing contaminants than recombinant, and were never put through human trials like the recombinant versions, so there's yet another set of unknowns.
So, is it a proven fact or just another theory? Any actual time frame for these breaks?
Any recommendations or where to find data to read about proper breaks? Also where did you see the data on how effectiveness reduction after cessation.
.. ok let’s have it ..
Ghoul
Well-known Member
Declan what do you want? You didn't want studies, you wanted first hand experiences and got them.
Now you don't want theories, you want data. You want certainty, a manual spelling everything out in detail with enough data to eliminate all ambiguity.
All I can tell you is my experience, and of others, who use them continuously and experienced no further drop off in efficacy. We know thousands of closely monitored trial subjects had no drop off in efficacy over the course of years of continuous use, being 2 to 3 years passed any additional weight loss or side effects at the final dose they stayed on permanently. They're not regaining weight.
Do what you want. Go on and off, use whatever protocol. Maybe it'll be just fine. Maybe in a few years there will be some explanation for what's being experienced. Maybe after 25 cycles none of the drugs in this class will work for you ever again, or perhaps your immune system turns on the natural form of GLP and GIP as a result, with some terrible health impact. God knows we have a long list of unintended medicine consequences only discovered after many years.
All I can do; if I'm going to keep using this stuff, is try to minimize my risk from exposure to the unknown by sticking as closely to the methods used that have proven safe for a lot of people over an extended period of time. "Millions of patient years of experience" is the relevant expression. Maybe I've already fucked myself by using a peptide made in the basement of some Beijing dry cleaner. Who knows. We're all a bunch of Magellan's out here. Only time will tell.
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Alias Chosen
New Member
That Telegram is nuked. You can find the new one on their updated price list, available on one of these pages. Move fast, a lot of stuff is going quick and prices will be going up.
Ghoul
Well-known Member
Right there bud. Hit that button and all past and future posts by the user disappear from view. It's an awesome feature, because it lets you be your own moderator, banning anyone you want from your world here at MESO.
I can relate. Can't stand low effort members, but rather than try to control what others get to read, I just worry about myself and who I don't want to see, and *poof*, they're gone.
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