Letits now
Member
I did have some fatty liver issues but I had attributed that to the phenibut I was taking for a while. Plus I was 50 pounds heavier.
MESO-Rx
Anabolic Steroids
Qingdao Sigma Chemical Co., Ltd (International, US, EU, Canada and Australia domestic
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BamaCrazy
New Member
My resting HR went from 57 to 64 on Reta. Even higher would be a safe number.
BP_6
Member
Thanks for the explanation. I asked because I on occasion have the same issue and it was even verified with a CAT scan as minor non specific inflammation. Which is funny because you read gut swelling can be a side effect of tirz so who knows. I might give it a try just to see.
DeeX
New Member
I've been on 12 for a couple months now.
Took about 6 weeks to kick in...and when it does, it kicks in hard. I haven't been hungry on Reta since second week of 4 mg.
I wear a CGM now bc I went hypoglycemic when on Ozempic originally earlier this year (<30 glucose).
Context for rest of post: 1200 calories per day max, high protein low carb diet, supplementing with multivitamins, blood tests every few weeks to confirm everything is going perfectly.
Semaglutide experience: okay, hunger would come back end of every week, insane constipation + burping + acid reflux. HRV absolutely tanked, but stayed on it until hitting 1.7. Lost ~1/ lbs per week. Fatigued like crazy.
Tirzepatide: great, burping continued, but other side effects were mildly existent...laxatives + electrolytes made everything better. Titrated up to 10 mg, was losing 1.5 lbs/week.
Retatrutide: excellent, all side effects have gone away aside from burping. I do wake up middle of the night needing to chug water and am needing to drink electrolytes multiple times per day. On 12 mg dose, losing ~3.5 lbs/week. I am 20 lbs from my goal weight right now and normal weight range, losing weight hasn't slowed though.
Fatigued lasted a couple weeks on Reta, until I started to eat way more protein.
Letits now
Member
It’s an amazing product.
I’m reading on here to see if there’s a better pairing with the hgh considering the insulin effect.
I personally get sides from Reta at 9mg per week pinning 3mg Monday/Wednesday/Friday.
I get hyperesthesia. It was manageable but unpleasant enough for me to take 10 days off.
Then this week I went back to reatatrutide and I'm experiencing it again although it's very mild this time. I was going to take another dose tomorrow but I am now considering sticking back to Tirzepetide for this coming week and just swapping compounds each week.
I get hyperesthesia. It was manageable but unpleasant enough for me to take 10 days off.
Then this week I went back to reatatrutide and I'm experiencing it again although it's very mild this time. I was going to take another dose tomorrow but I am now considering sticking back to Tirzepetide for this coming week and just swapping compounds each week.
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I found appetite control with reta as good as tirz and I really think the glucagon burns more fat than we think.
After trying both I highly recommend reta over tirz.
BamaCrazy
New Member
I’ve heard some call it allodynia. People have reported it on all GLPs. I also get it using Reta but didn’t on Tirz. It’s a minor nuisance that fades 2-3 days after injection.
BP_6
Member
Wow <30 blood glucose. Surprise you didn't pass out. Couldn't have felt too good.
DeeX
New Member
Felt like I was completely plastered when I tried to move at the end of a work meeting. Did a finger test and boom, "<30".
Guess I'm lucky that I'm not diabetic.
LGOP528
Member
HR returns to normal about a week and a half of stopping Reta. At least it did for me.
BP_6
Member
Anyone know through what mechanism it increases HR?
Not for me. Mine lasted 10 days after my last administration of Reta.
It was very annoying and irritating for 5-6 days. I took ten days off and it subsided.
I intend on staying on tirz indefinitely. Unless price or some long term studies show it is an issue. I'm lowering the dose as I bulk. I'll raise it up when I wanna cut again.
Next year I may wanna try reta. Plan is to introduce it at lowest dose. And slowly lower tirz till it's gone. But this is a plan. It's mainly for curiousity. Part of me is thinking if tirz worked so well why fix something that's not broke.
Next year I may wanna try reta. Plan is to introduce it at lowest dose. And slowly lower tirz till it's gone. But this is a plan. It's mainly for curiousity. Part of me is thinking if tirz worked so well why fix something that's not broke.
DugPrime
⚠️ Alternate account for @VSL Research ⚠️
You have to cycle it; otherwise, you’ll desensitize your GLP/GLP-1 receptors over time. Why not use it during the cut and switch to metformin during the bulk?
MyNameIsJeff
Member
this thread right now:
Letits now
Member
Let us know if it works.
Ghoul
Member
The extended phase clinical trials of both Tirz and Sema, going out 3 and 4 years respectively, clearly demonstrate once a "maintenance dose" is reached, weight loss is durable for years and side effects virtually disappear. If "desensitization" were a thing, they'd regain weight over time.
What has been observed by researchers and clinicians is interrupting GLP use, then returning, even years later, results in a weaker response to the drug, requiring higher doses for the same effect. Each time one of these "breaks" occurs response to the weight loss effect gets weaker, even across different GLP compounds.
The mechanism causing this is unclear, but might explain why in clinical trials 96%+ of participants following "boring" single GLP drug pharma protocols lose massive amounts of weight successfully, but at the Reddit Clinic, the people jumping on and off, switching compounds, injecting 5 times a week, and stacking just can't seem to drop the 10lbs they've been trying to for the last 6 months....
Superchicken
Member
I think the anti inflammatory benefits aren’t talked about enough. My husband’s using 2.5 and no longer has a dairy intolerance. He didn’t gaf before, and would just suffer the consequences since Lactaid didn’t consistently work. It prob didn’t work because he’d go buck wild with consumption. He doesn’t even take it anymore and can eat dairy like it’s never bothered him.
I recently started with half the starting dose, hoping to cut inflammation from Hashimoto’s and reduce the risk of getting more autoimmune diseases. I just had labs done and my antibodies were low, but will be interesting to see how/if it changes. Have read multiple stories of others with different autoimmune diseases, reducing meds or coming off completely while being on tirz.
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