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You take only this? Or also 2.5/5mg cialis? Or anything else?

I take low dose cialis, and oral minox, but the effect from both on BP is minimal. A point or two, max.

Started on 160 Valsartan before 80mg Telm, then 40mg Telm/5 Amlodipine.

The synergy of multi class BP meds makes 1+1=4 , with the side effect profile of a single low dose med. They're pushing pharma companies to offer even lower dose 3 class (adding a microdose diuretic) tabs for better results and even lower chance of sides.

IMG_9917.webp

 
I take low dose cialis, and oral minox, but the effect from both on BP is minimal. A point or two, max.

Started on 160 Valsartan before 80mg Telm, then 40mg Telm/5 Amlodipine.

The synergy of multi class BP meds makes 1+1=4 , with the side effect profile of a single low dose med. They're pushing pharma companies to offer even lower dose 3 class (adding a microdose diuretic) tabs for better results and even lower chance of sides.

View attachment 308381

Low dose cialis keeps me pretty close to 120/80 regularly. I have thought about getting some telm to keep on hand just in case it’s needed.
 
Low dose cialis keeps me pretty close to 120/80 regularly. I have thought about getting some telm to keep on hand just in case it’s needed.

Just keep in mind that generally, all BP meds take 2 weeks or so to realize the full effect, and sides are front loaded for the first month. After that sides usually disappear since the body recalibrates, clamping down on certain vessels to ensure, for instance, the brain gets enough pressure to offset fatigue and micro vessels in the extremities stop leaking excess water. So patience is needed and long term, consistant use is best. Upping the dose on cycle is fine, but hopping on and off completely should be avoided.
 
Did anyone's package stopped moving after clearing customs/delivered to local carrier ? It's been sitting there for 11 days, I don't see any reason why it shouldn't move to next stages, since it was cleared by the customs.

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Just keep in mind that generally, all BP meds take 2 weeks or so to realize the full effect, and sides are front loaded for the first month. After that sides usually disappears since the body recalibrates, clamping down on certain vessels to ensure, for instance, the brain gets enough pressure to offset fatigue and micro vessels in the extremities stop leaking excess water. So patience is needed and long term, consistant use is best. If needed upping the dose on cycle is fine, but hopping on and off completely should be avoided.
This might be a dumb question but is there a general rule of thumb of how much roughly 40mg telmisartan will lower BP? Should one start out at 20mg?
 
This might be a dumb question but is there a general rule of thumb of how much roughly 40mg telmisartan will lower BP? Should one start out at 20mg?

The guidelines offer standard starting doses for adults, regardless of BP, unless it's very high. For Telm it's 40mg, then an adjustment up or down as necessary.

Response varies widely which is why they don't say "use x dose to lower pressure x amount".

But, in the clinical trials, the mean amount of reduction for telm was:

20mg 7/6
40mg 9/7
80mg 12/8

For Telm/Amlodipine (Twynsta)

40/5mg 27/18
 
The guidelines offer standard starting doses for adults, regardless of BP, unless it's very high. For Telm it's 40mg, then an adjustment up or down as necessary.

Response varies widely which is why they don't say "use x dose to lower pressure x amount".

But, in the clinical trials, the mean amount of reduction for telm was:

20mg 7/6
40mg 9/7
80mg 12/8

For Telm/Amlodipine (Twynsta)

40/5mg 27/18
Do you notice any negative side effects from the addition of amlopidine?
 
I realize they originate from separate issues (legislation to allow taxing thaaangs....and yeah, yeah, the "war on Fentanyl" that'll just move through Mexico now), i have a hard time believing the sudden crackdown is totally unrelated.

But yeah I'd be lying if I claimed I follow any of this closely at all aside from your updates. I've been at least emotionally prepared for this. Paying for Christmas kept me from stockpiling but no meds I can't acquire legally...just an extra pain in the ass since my 132/78 BP and LDL of 142 are considered fantastic by my PCP (I mean I appreciate not adding diagnoses to my medical file but I'm gaslit into being told my numbers don't warrant treatment...scary times in medical competence... especially with a father that died of complications from coronary artery disease).

But I digress. Back to everyone's wait on the New Year's promo...or page 4000 promo,. whichever comes first..just doing my part!
Yeah pretty normal a lot of doctor now don’t want to scared their patient that’s why he told you that
 
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Pharma GLPs are recombinant. made by yeast with reprogrammed DNA. UGL is synthesized, resulting in small differences that make the peptide appear less natural to the immune system, and when they degrade, as all peptides do, the degradation products are different. Pharma has to test these degradation products, while labs synthesizing GLPs don't do the same, obviously.



View attachment 307045View attachment 307044

what evidence do u have?
 
And all BP meds are cheap, there's no excuse. 5 months worth for $20 is hardly rare, even for the "combo" ARB/CCB class BP meds, the gold standard first line treatments now. Much better than a higher dose single med.

View attachment 308373
I love reading your posts. I should do something about my BP too. Not high but definitely not 120/70

What source has this? I checked out pctzone and cosmicpct but couldn't find the AM variant.

Thanks for the education!
 
I wonder how many heads explode when trump shuts flow from china for 4 years and factories start making other things.... ... .
The Rich would be okay, as will be the homebrewers/stockpilers. For those that argue about $10 vs 15$ shipping, It will be back to the good old days.. when everything was rosy and peachy. When needles were picked from dumpsters to be boiled and reused, and multiple discarded vials of gear were rinsed, and the salvaged gear mix was seived with a handkerchief and decanted and injected. Of course we won't use CDs or Magazines to code gear. We will have Uber-gear and Gear-dash.. open to a select few. Tracy would be a thing of the past... Folks would come back to this thread and reminisce about how they mocked testing... as they inject salvaged gear
 
Do you notice any negative side effects from the addition of amlopidine?
I added Amlodipine 3-4 days ago and I’ve had moderate insomnia. But I also added low dose NPP 1 week ago and both cause insomnia for some users. If it persists I’ll drop NPP first and see if it improves
 
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