Qingdao Sigma Chemical Co., Ltd (International, US, EU, Canada and Australia domestic

[RandallFlagg]

Get that shit down to 120/70 or less. It's literally the single most significant factor in avoiding dozens of long term health issues.

Fuck PCPs. For the last few years now the world's leading preventive cardiologists have been pounding the table in anger over the negligence of front line doctors when it comes to BP.

Anything over 120/70 is now considered elevated in both the EU and US by the major cardio orgs, , because the evidence of harm is overwhelming, but most primary care docs are working on 30 year old standards.

The flow charts used to decide what to use are easy to follow, and more often than not a combo of very low dose meds can get you to ideal BP with no sides.

I went from 150/90 to 115/68 with no sides, using Telmasartin/Amlodipine 40/5, one tab a day, zero side effects. It's so easy. The lowest hanging long term health fruit there is .

The #1 treatment for high BP in the US is "keep an eye on it".

Yeah, I stocked up on Twynsta a while back. I started it but switched to just Telmisartan because of some insomnia (but turns out I think I just needed to back off the Test dose and it wasn't the Twynsta).

Gonna give it another run probably this week. I totally agree with needing to get it down. The problem is around here even most cardiologists either agree with the terrible guidelines or they do a poor job articulating their disapproval. (Probably because the almighty health insurance gods do not approve using meds even remotely to promote longevity).

Admittedly, doing some cardio would also do me some wonders but I'd be lying if I said that was starting this week...lol.

 

[glpfun]

I recommended stocking up while everything was still plentiful and cheap, but not because my crystal ball saw this crackdown on raws coming. The de minimus nightmare is yet to come, and unfortunately this raws shortage couldn't have come at a worse time. A least there seem to be enough for the basics floating around and sitting in freezers so things like Test Cyp will be uninterrupted for a long time, hopefully at least until all this settles down, the market stabilizes and either raws start to flow again or new producers emerge.

All the vendors are massively fucking up right now, Tracy sending wet products and not replacing, really shitty test results not being called out I’m sure vendors are hoping someone who doesn’t know any better will buy it without looking for test results. SSA just sending partial orders and dragging their feet for months to replace. SRY WTF someone sending hot packages or something I can’t even follow all the nonsense. Terrible time to purchase imo. September and October were great tho.

 

[Ghoul]

Yeah, I stocked up on Twynsta a while back. I started it but switched to just Telmisartan because of some insomnia (but turns out I think I just needed to back off the Test dose and it wasn't the Twynsta).

Gonna give it another run probably this week. I totally agree with needing to get it down. The problem is around here even most cardiologists either agree with the terrible guidelines or they do a poor job articulating their disapproval. (Probably because the almighty health insurance gods do not approve using meds even remotely to promote longevity).

Admittedly, doing some cardio would also do me some wonders but I'd be lying if I said that was starting this week...lol.

I'd say BP is the one area insurance companies don't push back on much. Probably because the meds are so damn cheap and their own data shows keeping BP in check unquestionably reduced their costs.

It's just that docs look at it as "I'll be retired before this becomes a problem." and patients with stage 2 hypertension are "I feel fine, I'm not taking any damn pills".

They don't call it "The silent killer" for nothing.

But you don't need docs or insurance to easily manage this yourself. There are threads here on Meso showing exactly how to go step by step and figure out what you need, using the most up to date clinical guidelines. It's the kind of thing you can just call your doctor about and 95% of the time they'll just write a script for what you tell them you want. They're happy you did their job for them.

 

[Juiced_lizard]

And all BP meds are cheap, there's no excuse. 5 months worth for $20 is hardly rare, even for the "combo" ARB/CCB class BP meds, the gold standard first line treatments now. Much better than a higher dose single med.

View attachment 308373

You take only this? Or also 2.5/5mg cialis? Or anything else?

 

[Deezznutzz]

Been using the 273.22mg Test C blue tops from the testosterone apocalypse pre orders. All came crashed so I put all 10 vials on my coffee pot burner at once. Fixed in 3 min minutes. Zero pip and smooth even at this high of a concentration. Looking forward to trying the mast e soon after it lands. Thanks @Qingdao Sigma Chemicals for the high quality oils and for saving me some money.

 

[Ghoul]

You take only this? Or also 2.5/5mg cialis? Or anything else?

I take low dose cialis, and oral minox, but the effect from both on BP is minimal. A point or two, max.

Started on 160 Valsartan before 80mg Telm, then 40mg Telm/5 Amlodipine.

The synergy of multi class BP meds makes 1+1=4 , with the side effect profile of a single low dose med. They're pushing pharma companies to offer even lower dose 3 class (adding a microdose diuretic) tabs for better results and even lower chance of sides.

2024 ESC Guidelines for Management of Elevated BP and Hypertension: Key Points - American College of Cardiology

John D. Bisognano, MD, PhD, FACC

www.acc.org

 

[Juiced_lizard]

I take low dose cialis, and oral minox, but the effect from both on BP is minimal. A point or two, max.

Started on 160 Valsartan before 80mg Telm, then 40mg Telm/5 Amlodipine.

The synergy of multi class BP meds makes 1+1=4 , with the side effect profile of a single low dose med. They're pushing pharma companies to offer even lower dose 3 class (adding a microdose diuretic) tabs for better results and even lower chance of sides.

View attachment 308381

2024 ESC Guidelines for Management of Elevated BP and Hypertension: Key Points - American College of Cardiology

John D. Bisognano, MD, PhD, FACC

www.acc.org

Low dose cialis keeps me pretty close to 120/80 regularly. I have thought about getting some telm to keep on hand just in case it’s needed.

 

[Ghoul]

Low dose cialis keeps me pretty close to 120/80 regularly. I have thought about getting some telm to keep on hand just in case it’s needed.

Just keep in mind that generally, all BP meds take 2 weeks or so to realize the full effect, and sides are front loaded for the first month. After that sides usually disappear since the body recalibrates, clamping down on certain vessels to ensure, for instance, the brain gets enough pressure to offset fatigue and micro vessels in the extremities stop leaking excess water. So patience is needed and long term, consistant use is best. Upping the dose on cycle is fine, but hopping on and off completely should be avoided.

 

[0x33]

Did anyone's package stopped moving after clearing customs/delivered to local carrier ? It's been sitting there for 11 days, I don't see any reason why it shouldn't move to next stages, since it was cleared by the customs.

 

[Juiced_lizard]

Just keep in mind that generally, all BP meds take 2 weeks or so to realize the full effect, and sides are front loaded for the first month. After that sides usually disappears since the body recalibrates, clamping down on certain vessels to ensure, for instance, the brain gets enough pressure to offset fatigue and micro vessels in the extremities stop leaking excess water. So patience is needed and long term, consistant use is best. If needed upping the dose on cycle is fine, but hopping on and off completely should be avoided.

This might be a dumb question but is there a general rule of thumb of how much roughly 40mg telmisartan will lower BP? Should one start out at 20mg?

 

[Ghoul]

This might be a dumb question but is there a general rule of thumb of how much roughly 40mg telmisartan will lower BP? Should one start out at 20mg?

The guidelines offer standard starting doses for adults, regardless of BP, unless it's very high. For Telm it's 40mg, then an adjustment up or down as necessary.

Response varies widely which is why they don't say "use x dose to lower pressure x amount".

But, in the clinical trials, the mean amount of reduction for telm was:

20mg 7/6
40mg 9/7
80mg 12/8

For Telm/Amlodipine (Twynsta)

40/5mg 27/18

 

[Spaceman Spiff]

You take only this? Or also 2.5/5mg cialis? Or anything else?

Cialis is for pulmonary hypertension. Not regular hypertension

 

[Trenbolonetax]

The guidelines offer standard starting doses for adults, regardless of BP, unless it's very high. For Telm it's 40mg, then an adjustment up or down as necessary.

Response varies widely which is why they don't say "use x dose to lower pressure x amount".

But, in the clinical trials, the mean amount of reduction for telm was:

20mg 7/6
40mg 9/7
80mg 12/8

For Telm/Amlodipine (Twynsta)

40/5mg 27/18

Do you notice any negative side effects from the addition of amlopidine?

 

[17SS]

Do you notice any negative side effects from the addition of amlopidine?

You may hold a little water with Amlodipine. It takes a while to kick in so I take 5mg 2x day.

 

[Bigbicep]

Bro shout out to QSCs new stealth shipping! Been I few months since I ordered and this is definitely a level up. Opened it and was like wtf is this. Sorta still feel like i got someones random package oF XXXXX lol

 

[Anonymous35]

I realize they originate from separate issues (legislation to allow taxing thaaangs....and yeah, yeah, the "war on Fentanyl" that'll just move through Mexico now), i have a hard time believing the sudden crackdown is totally unrelated.

But yeah I'd be lying if I claimed I follow any of this closely at all aside from your updates. I've been at least emotionally prepared for this. Paying for Christmas kept me from stockpiling but no meds I can't acquire legally...just an extra pain in the ass since my 132/78 BP and LDL of 142 are considered fantastic by my PCP (I mean I appreciate not adding diagnoses to my medical file but I'm gaslit into being told my numbers don't warrant treatment...scary times in medical competence... especially with a father that died of complications from coronary artery disease).

But I digress. Back to everyone's wait on the New Year's promo...or page 4000 promo,. whichever comes first..just doing my part!

Yeah pretty normal a lot of doctor now don’t want to scared their patient that’s why he told you that

 

[Deezznutzz]

Did anyone's package stopped moving after clearing customs/delivered to local carrier ? It's been sitting there for 11 days, I don't see any reason why it shouldn't move to next stages, since it was cleared by the customs.

View attachment 308383

Normal. Mine does that often. Carrier takes it's time to move to usps even when it's just down the street.

 

[Deezznutzz]

Bro shout out to QSCs new stealth shipping! Been I few months since I ordered and this is definitely a level up. Opened it and was like wtf is this. Sorta still feel like i got someones random package

It's not steath if you brodcast it online.

 

[gotmyles]

Thank God for qsc. Honorary American. He's the only reason I can abuse my health so affordably.

Also got my clonidines and propranolol from pct247, to obsess less over trackings

 

[clearheaded]

I

Pharma GLPs are recombinant. made by yeast with reprogrammed DNA. UGL is synthesized, resulting in small differences that make the peptide appear less natural to the immune system, and when they degrade, as all peptides do, the degradation products are different. Pharma has to test these degradation products, while labs synthesizing GLPs don't do the same, obviously.



View attachment 307045View attachment 307044

what evidence do u have?