Question about response, dose and health parameters

[giorgio_]

Some people might reach much higher levels of free T on the same dosage than others. For example, 300mg of test a week puts me on 1.5k ng/dl, so not exactly a hyper-responder

I want to ask, when it comes to managing the side-effects & health parameters, what is actually the important stat - the dose, or the test level?

For example, is someone who gets 2k ng/dl from 300mg really better off than someone who is at 1.5k? Because the lower responder can just take more gear to get to the same level

Like for example the lipid profile, hematocrit & the blood pressure are correlated to the testosterone level, and not the dose right?

 

[smartgear]

The side effects are caused by the blood level concentration, not the solution from the vial.

If 200 mg a week puts you below 1,000 ng/dL, you won't experience side effects and elevated e2, because below 1,000 ng/dL is basically the natural reference range.

If the same dose puts you at a testosterone level significantly above the reference range, then you will likely experience side effects if you are prone.

Total testosterone and free testosterone are two different things, which one do you measure?

Estradiol is converted from free testosterone. Basically, the more total testosterone you have, the more free testosterone and e2 you will have (the process is not linear).

Whether you will get side effects or not, it depends on whether you are prone or not. In my case, for example, 250 mg of testosterone enanthate give me 5,000 ng/dL of total testosterone and 500 pmol/L of e2 around 12 hours after injecting. And I'm not experiencing even a single e2 side effect.

To answer the question in the last paragraph: Yes, they are related to the level, not the dose.

The side effects of testosterone are caused by the levels, not the doses.

 

[readalot]

250 mg [sic] of testosterone enanthate give me 5,000 ng/dL

250 mg/week of Test E gets you to 5k ng/dl TT?

Injection frequency and relation to when you pull bloods?

What's your SHBG?

Nice summary on the FT / E2 relationship.

 

[smartgear]

250 mg/week of Test E gets you to 5k ng/dl TT?

Injection frequency and relation to when you pull bloods?

What's your SHBG?

Nice summary on the FT / E2 relationship.

Yes, it's 5,000 total testosterone.

Usually, I'm injecting it 2 times a week, but sometimes I let around 10 days to pass before I inject again. At the 10-13th day, the total testosterone levels are slightly above 300 ng/mL, which is near hypogonadal level.

I'm doing blood tests around 12 hours after injecting.

Sometimes, when I'm having a break, I will let the testosterone level to go low before I inject again. In such case, I'm not in a hurry to keep androgen levels high.

As for SHBG, it's well below the reference range: 11.59nmol/L (reference range: 18.30 - 54.10).

 

[readalot]

the 10-13th day, the total testosterone levels are slightly above 300 ng/mL,

ng/dl.

Wow, incredible response. Appreciate the reply.

 

[readalot]

Yes, it's 5,000 total testosterone.

Usually, I'm injecting it 2 times a week, but sometimes I let around 10 days to pass before I inject again. At the 10-13th day, the total testosterone levels are slightly above 300 ng/mL, which is near hypogonadal level.

I'm doing blood tests around 12 hours after injecting.

Sometimes, when I'm having a break, I will let the testosterone level to go low before I inject again. In such case, I'm not in a hurry to keep androgen levels high.

As for SHBG, it's well below the reference range: 11.59nmol/L (reference range: 18.30 - 54.10).

And you sure it is Test E not Test P?