Retatrutide

[gotgrowth]

Looking to start retatrutide a source I’m looking to buy from had 10,15 and 20mg. But his 10mg came in at 97 percent purity while his 15 and 20 came in at 99

My question if i start at 2mg a week will the 15mg last once reconstituted for 8 weeks ish ?

 

[startingover58]

By the time the peptide gets to you, the 99% could be 94% and the 97% could still be 97%, so don't concern yourself too much with that. 96% or above imo is fine.

Pharma reconstituted GLPs (pens) last for two years under refrigeration. That's under perfect conditions you cannot replicate.

User reconstituted pharma proteins in multi dose containers, using the specific BAC they supply, are universally instructed to be discarded after 28 days.

No one can say for certain how long before a UGL peptide degrades. On top of all the variables, each batch will vary in stability as well.

What you can do to maximize its life is the following.

-Use real pharma grade BAC like Hospira.

-Use high quality syringes, like BD, to minimize the amount of silicone lubricant introduced into the vial when reconstituting. Silicone droplets promote degradation.

-Dilute to the same ratio used by pharma, or more, but never less.

-Exercise discipline in wiping vial top every time with an alcohol swab, and allow to dry, so you minimize introducing more bacteria.

-Of course refrigerate, protect the vial from light in an opaque container.

-Allow the reconstituted solution, in its opaque container, to come to room temp, 10 minutes or so before opening the outer container and using. This will prevent bacteria laden condensation from forming on the vial.

-Minimize vial agitation after reconstitution. Don't keep it in a refrigerator drawer that's frequently opened, for instance.



The more of these steps you follow, the longer Reta, or any reconstituted peptide will last.

Doing what you can / are willing to is better than not doing any of them.

All of that said, 7-8 weeks is rarely a problem, but it's always a good idea to protect as much potency as you can anyway. The products of protein degradation can have other undesirable effects.

For the truly obsessed:

-If you're really intent on doing everything possible to minimize any potential source of degradation, use a .2 or .22 PES low protein adhesion syringe filter and transfer the reconstituted solution into a sterile, pyrogen free container, at the cost of some product.

-Finally, the ultimate you can do to ensure you're injecting the best version of the peptide is to syringe filter the dose into the syringe just before administration.

Damn great info!!
Im big on peptides.Told freezing extemds shelf life?ya have any thougts or knowledge concerning freezing?ive done this for quite sometime now.
Cant say i noticed any differance..
But what the fuck do i know..lol

 

[undersc0re]

Is efocipegtrutide an option to retatrutide anywhere or are they pretty much just the same thing?

 

[TestyisBesty]

With all the talk of starting Reta at 2mgs for a 225lb 15% bf male could possibly be a waste, anyone start out at 4mgs and not face severe side affects?

 

[Phishphan]

With all the talk of starting Reta at 2mgs for a 225lb 15% bf male could possibly be a waste, anyone start out at 4mgs and not face severe side affects?

At minimum take 2mg for 2 weeks, then 3mg for a week, then try 4mg on week 4

 

[Bocagang]

Looking to start retatrutide a source I’m looking to buy from had 10,15 and 20mg. But his 10mg came in at 97 percent purity while his 15 and 20 came in at 99

My question if i start at 2mg a week will the 15mg last once reconstituted for 8 weeks ish ?

Hey man, I don’t have the ability to DM here yet.

Would you mind sending me a DM on your source. I have bought everything through Opti, which honestly has been amazing.

But it’s 100 bucks for 4mg . Which to my understanding is like one dose once you get going. I would love to order form options here but I can’t afford it.

You would be doing me a huge favor. I hear the cognitive benefits here are great and also assist with adhd m. Which is a major problem I have struggled with adhd since I have been 8 years old. That * some weight loss has me super excited.

Thank you in advance for your kindness should you be able to share. I just can’t afford opt in this one.

 

[lamehack]

tried 2mg reta and my blood glucose was diving really hard. like 55ng/dl post gym and that after consuming 70g of carbs pre-workout. i wasn't hungry, as my typical lunch of 400g beef was impossible to consume, i could barely do 150g. but I had insane night time sugar cravings.
so i do wonder if doing reta+keto for a cut would be the way to go, to avoid glucose rollercoaster.
will give it another try, anyone here noticed weird energy/glucose side effects? like one day your workouts are amazing, then lethargy. i hate a bit that lack of predictability

 

[Here2Learn]

Hey man, I don’t have the ability to DM here yet.

Would you mind sending me a DM on your source. I have bought everything through Opti, which honestly has been amazing.

But it’s 100 bucks for 4mg . Which to my understanding is like one dose once you get going. I would love to order form options here but I can’t afford it.

You would be doing me a huge favor. I hear the cognitive benefits here are great and also assist with adhd m. Which is a major problem I have struggled with adhd since I have been 8 years old. That * some weight loss has me super excited.

Thank you in advance for your kindness should you be able to share. I just can’t afford opt in this one.

You are literally in the space that has every source you could dream of, may need to spend some time reading the intro posts and wandering around a bit. No one is going to spoon feed you on this forum.

 

[Rakusa]

Whats your opinion of the best supplements to add to reta?

For fat metabolism obviously q10, carnitine, methylene blue comes to my mind, but I am more interested in a micronutrient way. Is there anything that you should add to reta, as a "ease of life" or wellbeing addon?

 

[NotHuman]

I’ve been using Retatrutide for close to four weeks (I made a thread on Pro Muscle). I was doing the 0.5mg EOD micro dose thing but after reading this thread, I might switch to 1mg 2x per week. Psychologically, it’s hard to bring myself to do once a week dosing, but we will see.

Everything has been great so far, other than increased resting heart rate. I noticed an appetite reduction in less than a week. It’s not crushed though, only controlled, which is perfect. Cheat meals don’t seem to stay on my body. I wake up just as lean as if I didn’t have one. I lost maybe like 5lbs, even though that wasn’t my goal. My abs look ridiculous right now.

I plan to remain on this forever and see no point in altering my dosage. I am buying into the health benefits that aren’t weight loss induced.

 

[Sampei]

I’ve been using Retatrutide for close to four weeks (I made a thread on Pro Muscle). I was doing the 0.5mg EOD micro dose thing but after reading this thread, I might switch to 1mg 2x per week. Psychologically, it’s hard to bring myself to do once a week dosing, but we will see.

Everything has been great so far, other than increased resting heart rate. I noticed an appetite reduction in less than a week. It’s not crushed though, only controlled, which is perfect. Cheat meals don’t seem to stay on my body. I wake up just as lean as if I didn’t have one. I lost maybe like 5lbs, even though that wasn’t my goal. My abs look ridiculous right now.

I plan to remain on this forever and see no point in altering my dosage. I am buying into the health benefits that aren’t weight loss induced.

If you can without hindering your appetite too much, try to go to 4mg. That's where most of the health benefit start shining right.

 

[SubparMarioBro]

Do me a solid and find out what the dilution rates are for each dose, if you can. If it's in the Phase II or III documentation, it's firmed up and will be what's used for retail. I'm just spent when it comes to looking shit up.

6mg/ml for all doses per phase 2 documentation.

 

[Here2Learn]

6mg/ml for all doses per phase 2 documentation.

Interesting I had someone else in the study say their paperwork says 6mg .75ml

 

[SubparMarioBro]

Interesting I had someone else in the study say their paperwork says 6mg .75ml

Might be possible that they changed the concentration in other studies?

 

[Here2Learn]

Might be possible that they changed the concentration in other studies?

Very well could be!

 

[keenpen]

This is an interesting topic. Tirz is awesome and this thread seems to indicate that tirz is superior in at least 2 main areas as compared to reta. Tirz has better appetite control and it manages BG better.

Yet people switch to reta or jump right to reta. Why?

If tirz is working, is there any real reason to consider reta? I almost want to try it just cuz.

Lastly, to Mr my gunz are bigger than your gunz so I'm right and you're wrong - way to be a juvenile asshole. Some people are trying to learn here. Can't we all just get along? (Obviously, this is retorical)

 

[Ghoul]

This is an interesting topic. Tirz is awesome and this thread seems to indicate that tirz is superior in at least 2 main areas as compared to reta. Tirz has better appetite control and it manages BG better.

Yet people switch to reta or jump right to reta. Why?

If tirz is working, is there any real reason to consider reta? I almost want to try it just cuz.

Lastly, to Mr my gunz are bigger than your gunz so I'm right and you're wrong - way to be a juvenile asshole. Some people are trying to learn here. Can't we all just get along? (Obviously, this is retorical)

For most I think it's the assumption "newer=better". More recently avoiding "fatigue" has been given as a reason, yet nothing in the trials suggest Reta or Tirz are any different in this regard. You'd think it'd be touted as a major benefit.

So ultimately, and the reason for Reta's entire existence, is the higher average maximum potential weight loss vs Tirz.

I believe it was developed as Novo's answer to the potential threat of Eli's Cagri and/or high dose (7.2mg) Sema from them as well.

But the truth is the vast majority of overweight/obese can lose all they need with Sema or Tirz before hitting the limits of either.

I advise people also consider the availability/expense of staying on a maintenance dose indefinitely, a fact that's finally starting to be openly spoken of by docs. Reta's by far the least cost effective, while Tirz is a bit more than Sema, but not only has fewer sides, has tangible health benefits attributable specifically to GIP agonism which Sema lacks,

IMO, Tirz would benefit from a little more GLP agonism, simply by adding some Sema to the mix, but with Sema and Tirz patents held by competitors that's unlikely.

The other way would be just taking the Tirz molecule and adding more to the GLP agonist portion, but without a change to the law, we're going to be stuck with a limit of 39 aminos on peptide chains for the foreseeable future.

 

[Sampei]

This is an interesting topic. Tirz is awesome and this thread seems to indicate that tirz is superior in at least 2 main areas as compared to reta. Tirz has better appetite control and it manages BG better.

Yet people switch to reta or jump right to reta. Why?

If tirz is working, is there any real reason to consider reta? I almost want to try it just cuz.

Lastly, to Mr my gunz are bigger than your gunz so I'm right and you're wrong - way to be a juvenile asshole. Some people are trying to learn here. Can't we all just get along? (Obviously, this is retorical)

Because for who doesn't want to lose weight and appetite reta Is far superior

 

[Ghoul]

Because for who doesn't want to lose weight and appetite reta Is far superior

It's better for weight loss, but only 23% average at max dose with Reta vs 21% with Tirz.

As it is there's a big problem with the speed of weight loss and associated muscle loss.

 

[deadbeef]

This is an interesting topic. Tirz is awesome and this thread seems to indicate that tirz is superior in at least 2 main areas as compared to reta. Tirz has better appetite control and it manages BG better.

Anybody who is saying tirz is better than reta hasn't seen any of the reta phase 3 data.

 

[Sampei]

It's better for weight loss, but only 23% average at max dose with Reta vs 21% with Tirz.

As it is there's a big problem with the speed of weight loss and associated muscle loss.

Did you read what I wrote ghoul? Or am I missing something? Reta doesn't suppress appetite much so it's a lot better for bodybuilder that wanna reap the benefit of GLP1 without hindering their progress