MESO-Rx

Anabolic Steroids

Stanford Pharmaceuticals

@DannyP some people like to like the other compounds do the work and keep the rest just above normal or at normal. Some people like me experience sides with high test, anger, water retention, acne, higher BP, and lipids get fucked. It's all a self experiment. This is why we always say see what works for you and always get blood work. Pre, mid and post.
 
DannyP said:
No, I'll be running it 12 weeks.
Was thinking of trying a lower dose due to my e2 levels on last 2 cycles, can't seem to get it below 80 even with arimedix every day and some nolva thrown in twice a week.
Probably has something to do with my age (50), one of Dr. Rand's videos he talks about the older we get the more the body wants to convert test to estrogen.
Mother Nature wants us to slow down on the F****ing and fighting I guess.
Click to expand...

If your aren't experiencing any e2 sides don't worry about them being slightly elevated. Estergen also helps muscle growth.
 
Estrogen also plays a role in growth hormone production, the anabolic and lipolytic effects of which have been well elucidated. The bottom line is that without adequate estrogen, growth hormone levels will suffer, making it more difficult to both gain muscle mass and lose bodyfat. As an added benefit, estrogen enhances growth hormone receptor expression, further potentiating its effects in the body. In laymen’s terms, growth hormone works better in the presence of estrogen.

One should also expect an increase in Glut-4 translocation. Located within skeletal muscle, Glut-4 is a carrier protein which helps transport nutrients from the cell surface to inside the cell, where they can then be used for recovery and growth. Unless activated, Glut-4 remains within the cell, hibernating until it receives a signal to rise to the surface. However, under certain conditions Glut-4 can be rather stubborn, refusing to come up to the cell surface in adequate quantities even when signaled to do so. Estrogen improves the translocation (movement) of Glut-4 to the cell surface, permitting greater amounts of nutrients to permeate the cell barrier, where they will ultimately be used for muscle growth and repair.

As one of the most powerful suppressors of muscle growth in the human body, myostatin interferes with the growth process on multiple levels, one of which is by blunting mTOR—a central regulator of cell metabolism, growth, and proliferation. Even small elevations of this muscle destroying protein can make it more difficult to maintain currently existing muscle tissue, let alone acquire additional size and strength. To give you an idea of how powerful myostatin is, animals which have been genetically altered to ensure the absence of the myostatin gene exhibit drastically increased levels of muscle mass over their genetically intact peers. In many cases these animals will grow over 100% more lean tissue than non-treated animals; a massive increase to say the least.

However, we don’t need to be the object of genetic engineering in order to manipulate myostatin levels within the body. In clinical studies designed to evaluate the effects of training on myostatin in men and women, the elevated estrogen levels found in women were shown to have myostatin inhibiting effects in muscle tissue by down-regulating myostatin mRNA expression and reducing serum LAP/propeptide levels. This down-regulatory effect makes estrogen anti-catabolic in nature and therefore, a valuable component of the growth process.
 
Bigboy727 said:
Here is my 2 cents. Primo shines at week 14 and that’s the least I would run it and no lower than 600. The benefits I get from week 12-20 is what makes feeling like a pin cushion worth it. Lower your test for sure then. It only makes sense. I also have a found Aromasin to work better for me at 12.5mg EOD. This is my .2 cents. Let the primo shine and if you want some extra lean mass throw a nandrolone in. Keeping test Low will let the primo do it’s thing and I won’t have any sides. Well primo makes me generally feel great with lots of energy and focus. Pretty much the opposite of how Tren makes me feel..lol
Click to expand...
I’m leaning towards pinning npp Monday and Thursday with it’s 4 day half life. What do you think? That will be 500mg a week. Test at 300mg. Primo at 600mg.
 
TorroXL said:
I’m leaning towards pinning npp Monday and Thursday with it’s 4 day half life. What do you think? That will be 500mg a week. Test at 300mg. Primo at 600mg.
Click to expand...
Npp should be blasted M-W-F because it has a 2-3 day half life. Lower the test to 300-400, I match my test with nandrolones and run it for 20 weeks.
 
Last edited:
Bigboy727 said:
Npp should be blasted M-W-F because it has a 2-3 day half life. Lower the test to 300-400, I match my test with nandrolones and run it for 20 weeks.
Click to expand...
I’m only doing a short ester blast with npp. 8 weeks npp the 8 weeks Mast Prop. Primo the whole time. Test 300 as well. Mite have to cut the cruise a lil short;)
 
TorroXL said:
I’m leaning towards pinning npp Monday and Thursday with it’s 4 day half life. What do you think? That will be 500mg a week. Test at 300mg. Primo at 600mg.
Click to expand...
Looks awesome! Love npp. Keep us posted. You could do Mon/Wed/Fri but 2x a week will suffice. Npp keeps me looking full as well as pain free which is a plus.
 
ickyrica said:
If anyone in the greater Boston area is out of work lmk. I know a few large companies that are always hiring and do recognize talent from within. They pay for education as well. These jobs would be in electrical and technology. You will work hard at the begining of the journey but the ability to transition is there. They are not union fwiw but rate pay is a reality on many jobsites as a laborer, so that helps.
Click to expand...
Bigboy727 said:
View attachment 84055 Touchdown! Well I haven’t been this excited since I was 5 getting the He-Man Gray Skull Castle. Thanks @StanfordPharma! I’ll be running this cycle.

Test e 300 1-20
Primo 800 1-20
Npp 350 2-12
Anavar 50md ED 16-20
Click to expand...
I am going to try this cycle in April--- thank you for sharing
 
legendary said:
Estrogen also plays a role in growth hormone production, the anabolic and lipolytic effects of which have been well elucidated. The bottom line is that without adequate estrogen, growth hormone levels will suffer, making it more difficult to both gain muscle mass and lose bodyfat. As an added benefit, estrogen enhances growth hormone receptor expression, further potentiating its effects in the body. In laymen’s terms, growth hormone works better in the presence of estrogen.

One should also expect an increase in Glut-4 translocation. Located within skeletal muscle, Glut-4 is a carrier protein which helps transport nutrients from the cell surface to inside the cell, where they can then be used for recovery and growth. Unless activated, Glut-4 remains within the cell, hibernating until it receives a signal to rise to the surface. However, under certain conditions Glut-4 can be rather stubborn, refusing to come up to the cell surface in adequate quantities even when signaled to do so. Estrogen improves the translocation (movement) of Glut-4 to the cell surface, permitting greater amounts of nutrients to permeate the cell barrier, where they will ultimately be used for muscle growth and repair.

As one of the most powerful suppressors of muscle growth in the human body, myostatin interferes with the growth process on multiple levels, one of which is by blunting mTOR—a central regulator of cell metabolism, growth, and proliferation. Even small elevations of this muscle destroying protein can make it more difficult to maintain currently existing muscle tissue, let alone acquire additional size and strength. To give you an idea of how powerful myostatin is, animals which have been genetically altered to ensure the absence of the myostatin gene exhibit drastically increased levels of muscle mass over their genetically intact peers. In many cases these animals will grow over 100% more lean tissue than non-treated animals; a massive increase to say the least.

However, we don’t need to be the object of genetic engineering in order to manipulate myostatin levels within the body. In clinical studies designed to evaluate the effects of training on myostatin in men and women, the elevated estrogen levels found in women were shown to have myostatin inhibiting effects in muscle tissue by down-regulating myostatin mRNA expression and reducing serum LAP/propeptide levels. This down-regulatory effect makes estrogen anti-catabolic in nature and therefore, a valuable component of the growth process.
Click to expand...

Good stuff man thanks.
I always worried about worried about my somewhat elevated estrogen, but never had any negative sides that I noticed.
 
HIGHRISK said:
Is it beneficial at all to run a low dose of primo while cruising at 300 test a week?
Click to expand...

It's subjective to what your goals are.

Is it to put on giant amounts of muscles? Na won't be what you are looking for.

Is it to give you a heighten sense of well being along with the trt. Yup it will do that. Don't be looking for giant gains though. People forget that compounds at low dosages do add benefits other than mass, but most of us on here lean towards what gives men mass.

Another good thing to add to the trt line up is masterone. Low dose of masterone is cheaper typically and lowers your shgb while you are on your trt.
 
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