tren advice

[lucasj782]

starting tren e
probably 20 mg eod with 150 test
also on 6 iu growth 50 var 4 tirz 2 reta trying to run a 4-6 week minicut.
any advice on dosaging for tren to avoid sides. start lower? higher? pin everyday?
prone to mental sides and hair loss so a bit worried but fuck it tren hard anavar give up

 

[Jpxxx]

starting tren e
probably 20 mg eod with 150 test
also on 6 iu growth 50 var 4 tirz 2 reta trying to run a 4-6 week minicut.
any advice on dosaging for tren to avoid sides. start lower? higher? pin everyday?
prone to mental sides and hair loss so a bit worried but fuck it tren hard anavar give up

Tren ace is the way to go, then if u get sides itll pass quicker

 

[BALLISTIC]

starting tren e
probably 20 mg eod with 150 test
also on 6 iu growth 50 var 4 tirz 2 reta trying to run a 4-6 week minicut.
any advice on dosaging for tren to avoid sides. start lower? higher? pin everyday?
prone to mental sides and hair loss so a bit worried but fuck it tren hard anavar give up

This is a relatively smart start. With Tren, less is more. Depending on your split you're essentially looking at 80mg weekly with Ace. This will give you the ability to run longer and stronger without adverse reactions. I'm sure you've seen some of the dosing and it's unnecessary.

I have no advice on reference to Tirz stacked with Reta. I'm a solo Reta large dose believer.

6iu growth is solid depending on lab reports.

You could probably stand bumping test up, your decision.

 

[lucasj782]

This is a relatively smart start. With Tren, less is more. Depending on your split you're essentially looking at 80mg weekly with Ace. This will give you the ability to run longer and stronger without adverse reactions. I'm sure you've seen some of the dosing and it's unnecessary.

I have no advice on reference to Tirz stacked with Reta. I'm a solo Reta large dose believer.

6iu growth is solid depending on lab reports.

You could probably stand bumping test up, your decision.

i meant 150 test every other day so 525 a week. also reta alone def best for getting peeled but tirz appetite suppression is wild only 1-2 weeks on it but more appetite reduction than 6-8 reta for me

 

[hellerhiwater]

This is a relatively smart start. With Tren, less is more. Depending on your split you're essentially looking at 80mg weekly with Ace. This will give you the ability to run longer and stronger without adverse reactions. I'm sure you've seen some of the dosing and it's unnecessary.

I have no advice on reference to Tirz stacked with Reta. I'm a solo Reta large dose believer.

6iu growth is solid depending on lab reports.

You could probably stand bumping test up, your decision.

i recently heard (on yt from a content creator, who does technically have credentials but is a content creator first) that low dose tren with high test is a "Waste" bc tren competes for the receptor and wins every time

just curious of ur input bc ur sir ballistic, the based.

 

[hellerhiwater]

starting tren e
probably 20 mg eod with 150 test
also on 6 iu growth 50 var 4 tirz 2 reta trying to run a 4-6 week minicut.
any advice on dosaging for tren to avoid sides. start lower? higher? pin everyday?
prone to mental sides and hair loss so a bit worried but fuck it tren hard anavar give up

i did a fuckload of "research" on stacking glp-1s about a month ago bc i was interested in getting the glucagon effect from reta on top of my tirz.

there are a LOT of people who do stack them, and it seems to be relatively safe if the doses arent stupid. but a couple posts that seemed to be well-informed mentioned that they will essentially compete and then you get the effect of the stronger one so the weaker on loses. and apparently tirz is better at targeting glp and gip, so all but the glucagon from the reta is "wasted" or some shit, i dont remember fully but thats basically the gist.

im going to try and find the exact posts brb

 

[Astartes]

i recently heard (on yt from a content creator, who does technically have credentials but is a content creator first) that low dose tren with high test is a "Waste" bc tren competes for the receptor and wins every time

just curious of ur input bc ur sir ballistic, the based.

Almost no one will saturate their receptors so fully as to have tren truly compete to an adverse degree in application. These YT guys are spouting 1990s info. Might as well go back to myth of down regulation of receptors or ftg

 

[adrenalytic]

so 60 tren a week? or 80? 80 is where I started to feel on. It's a good compromise and you'll get the nutrient partitioning effect as well as glucocorticoid receptor activation. I'm not prone to mental sides or hair loss though so I can't speak to that.

 

[hellerhiwater]

Damn missed the edit window, though it doesn’t make a difference for the overall point, it should’ve read:

“Its GLP-1 receptor activity is roughly 2× stronger than Retatrutide’s, while its GIP receptor activity is about 5 to 9 times weaker (but once attached has a longer “residence time” than Reta GIP).“

Even though Reta has stronger potency at the GIP receptor, its faster off-rate and shorter residence time mean it binds, signals, and releases quickly.

When Tirz is sitting on those receptors Reta can’t simply bump it off, it just has to wait for a receptor to free up. Since Tirz dissociates slowly, very few openings appear and Tirz still monopolizes GIP sites,

Tirz also has a stronger albumin binding mechanism, and a steady, continuous rate of release. Reta detaches and reattaches much more dynamically (this gives Reta some kind of pulsatile advantage over Tirz I don’t quite understand yet), but it also means Tirz’s steadier plasma concentration is another reason it dominates shared receptors when both are in your system at the same time, throwing off Reta’s balance.

^^thats the main one i was referencing^^

here is the whole thread Stacking GLP's

 

[BigDadd7]

I've been running 100 tren e per week for months. I'm half bald and insane, but my lady loves that I'm a sex machine.

 

[BALLISTIC]

i recently heard (on yt from a content creator, who does technically have credentials but is a content creator first) that low dose tren with high test is a "Waste" bc tren competes for the receptor and wins every time

just curious of ur input bc ur sir ballistic, the based.

When it comes to certain compounds my opinion is less is more. Tren is certainly 1 of those along with Sdrol, and MTren, and Halo...for instance.

Consistently people hear “they both bind the androgen receptor” and jump to the idea that Tren somehow gets crowded out or made ineffective by high testosterone. That’s not how receptor pharmacology works in real human physiology.

Androgen receptors are not a single on/off light switchs. ARs are widely distributed throughout muscle, CNS, adipose, prostate, immune cells, etc. They're recycled constantly, and upregulated with androgen exposure.

High androgen load does not mean “full no room left.” If that were true, adding any second androgen would be useless, which we know is false from decades of real world outcomes. Even at low mg doses, Tren exerts disproportionate signaling effects compared to testosterone. This is signaling in parallel really.

People often misguide with how Tren works because they simply don't know. Tren alters glucocorticoid signaling (anti-catabolic this is a big one at low dose), strongly impacts IGF-1 expression, and has CNS effects unrelated to pure AR occupying. Tren drives nutrient partitioning via nongenomic (check my spelling) pathways.

50–150 mg/week Tren can dramatically alter body composition. It certainly increases strength disproportionate to scale weight anyone who's taken it knows this. Meanwhile it gives an enhanced hardness and look you can't miss unless your grossly playing outside your league and fat.

Meanwhile, 600to 1000 mg testosterone will be primary driving bulk, fullness, and the estrogenic environment. ←This part is important on Tren. Test acts as a foundation, not a replacement. These roles are complementary, not mutually exclusive.

I don't know who that gentleman is you speak of, I don't really get out much. Haha

But I'm confident very much so in saying he's wrong.

Edit: Here is a tidbit of dosing from various cattle studies. These are different in method of delivery. They are slow. So why are humans taking doses above what was given to 1000lb animals which returned incredible results? There was a gent here not long ago running 1g Tren, wondering why his kidneys were failing. Jeez I don't know fella. Haha

Revalor-G / TBA/E40 mg TBA + 8 mg E2
Estradiol. Used early in feeding/growth phase

Merck Animal Health USA
Revalor-S120 mg TBA + 24 mg E2 Estradiol
Mid-level finishing implant

DailyMed
Revalor-200 or Revalor-XS
200 mg TBA + 20–40 mg E2 Estradiol
High dose / long release
DailyMed +1

Synovex® one variants
50–200 mg TBA + 7–28 mg E2 Estradiol
Multiple dose strengths exist

Zoetis
Finaplix-H
200 mg TBA (no estradiol)
Pure trenbolone implant (without estrogen)

 

[bananafeet]

I saw a few steroid YouTuber videos come up on my feed.

Vomited in my mouth a bit.

I refuse to watch any of that stuff anymore (with exception to Think Big Bodybuilding Media content).

A lot of people are stuck in the mg trap. Lower mg of toxic compounds isn't safer.

Would you rather down a few litres of beer or a few millimetres of methylated spirits?

Sure at the hardware stores in some towns they got in trouble for storing it in the fridge for their clientele. But it's still ethanol right? It's just methylated. Can't be that bad? Right guys?

I hear if you microdose methylated spirits it has the same effect as drinking a few pints of beer. Should I start having it with my dinner?

 

[adrenalytic]

I hear if you microdose methylated spirits it has the same effect as drinking a few pints of beer. Should I start having it with my dinner?

I only drink 17α-alkylated moonshine.

 

[bananafeet]

Tren ace is the way to go, then if u get sides itll pass quicker

Tren ace is hell of a lot more addictive than tren enanthate. It hits harder for a lower dose.

starting tren e
probably 20 mg eod with 150 test
also on 6 iu growth 50 var 4 tirz 2 reta trying to run a 4-6 week minicut.
any advice on dosaging for tren to avoid sides. start lower? higher? pin everyday?
prone to mental sides and hair loss so a bit worried but fuck it tren hard anavar give up

What's with the micro dosing stacks these days? I can't advise blasting gear on a harm reduction forum but it seems like the shitness industry is doing this weird circle jerk advising weird stacks of drugs under the illusion it's safer.

Do TRT or do a cycle. Why muddy the lines?

It just seems so weird people will do low test with primo or micro dose tren but won't run a fat dose of testosterone.

I was guilty of this in the beginning doing these retarded cycles of 150mg test and 200mg deca and 400mg masteron and then 200mg primo. On these dumb arse cycles my bloods were worse than the exact same mg or more of mainly testosterone.

Anyway I'll see myself out.

 

[Elektrobot]

Look in the mirror and point to the part of your physique that absolutely can not get any better unless you start tren....

I looked at your pictures. You barely even look like you workout natty

Just run test and eat dude

 

[BALLISTIC]

Tren ace is hell of a lot more addictive than tren enanthate. It hits harder for a lower dose.


What's with the micro dosing stacks these days? I can't advise blasting gear on a harm reduction forum but it seems like the shitness industry is doing this weird circle jerk advising weird stacks of drugs under the illusion it's safer.

Do TRT or do a cycle. Why muddy the lines?

It just seems so weird people will do low test with primo or micro dose tren but won't run a fat dose of testosterone.

I was guilty of this in the beginning doing these retarded cycles of 150mg test and 200mg deca and 400mg masteron and then 200mg primo. On these dumb arse cycles my bloods were worse than the exact same mg or more of mainly testosterone.

Anyway I'll see myself out.

Man preach dude, I can run a 1g test cycle and benefit greater than a 500T 350Dec, 400Mast cycle. Hell I've run any cycle you can think of... Stacked to the max and pounding orals. Every now and then I go back to 1g T, and within 5 weeks I'm blown up, hyper vascular, loving life in the mood aspects. Best thing is with minor ancillaries my labs look great. Plus with needing more E2 these cycles just balance me and give natural aromatization where I feel balanced.

With that I do mess around, and currently I'm utilizing TNE 5 days a week pre, I've got Halo coming... But for me I use these as thrown in additives to boost that particular period. If it gets bad I can drop immediately. I guess curiosity is what gets me, like I'm searching for that extra "this works well"... Tren was great for me I gave it 3 strong blast and on one occasion while also using Sdrol, I was hospitalized. I'm honest and those doses of Tren still never broke 500mg. I'm going to eventually run again. But I'm going to introduce 100mg weekly, I can bet it will have a solid effect. I'm hoping that in this case low dose I can run cleaner and longer avoiding heart burn, night sweats, hypo BG, and if not "goodbye".

 

[bananafeet]

Man preach dude, I can run a 1g test cycle and benefit greater than a 500T 350Dec, 400Mast cycle. Hell I've run any cycle you can think of... Stacked to the max and pounding orals. Every now and then I go back to 1g T, and within 5 weeks I'm blown up, hyper vascular, loving life in the mood aspects. Best thing is with minor ancillaries my labs look great. Plus with needing more E2 these cycles just balance me and give natural aromatization where I feel balanced.

With that I do mess around, and currently I'm utilizing TNE 5 days a week pre, I've got Halo coming... But for me I use these as thrown in additives to boost that particular period. If it gets bad I can drop immediately. I guess curiosity is what gets me, like I'm searching for that extra "this works well"... Tren was great for me I gave it 3 strong blast and on one occasion while also using Sdrol, I was hospitalized. I'm honest and those doses of Tren still never broke 500mg. I'm going to eventually run again. But I'm going to introduce 100mg weekly, I can bet it will have a solid effect. I'm hoping that in this case low dose I can run cleaner and longer avoiding heart burn, night sweats, hypo BG, and if not "goodbye".

I've not gone into this because I can't prove it. But how do we know what the long term side effects are blocking catabolic pathways? Does it block breaking down non healthy cells, does it increase plaques or other weird protiens. The body has these pathways for a reason and giving yourself inverse diabetes doesn't sound smart.

That being said the use or tren or orals for me is kind of recreational drug use. No way in hell I would make them the main metabolic driver.

Reading this book's section on progestins has made me take a second look at nandrolone and go why am I injecting this shit:


I highly recommend reading any non bodybuilding books on hormones like this one.

 

[hellerhiwater]

When it comes to certain compounds my opinion is less is more. Tren is certainly 1 of those along with Sdrol, and MTren, and Halo...for instance.

Consistently people hear “they both bind the androgen receptor” and jump to the idea that Tren somehow gets crowded out or made ineffective by high testosterone. That’s not how receptor pharmacology works in real human physiology.

Androgen receptors are not a single on/off light switchs. ARs are widely distributed throughout muscle, CNS, adipose, prostate, immune cells, etc. They're recycled constantly, and upregulated with androgen exposure.

High androgen load does not mean “full no room left.” If that were true, adding any second androgen would be useless, which we know is false from decades of real world outcomes. Even at low mg doses, Tren exerts disproportionate signaling effects compared to testosterone. This is signaling in parallel really.

People often misguide with how Tren works because they simply don't know. Tren alters glucocorticoid signaling (anti-catabolic this is a big one at low dose), strongly impacts IGF-1 expression, and has CNS effects unrelated to pure AR occupying. Tren drives nutrient partitioning via nongenomic (check my spelling) pathways.

50–150 mg/week Tren can dramatically alter body composition. It certainly increases strength disproportionate to scale weight anyone who's taken it knows this. Meanwhile it gives an enhanced hardness and look you can't miss unless your grossly playing outside your league and fat.

Meanwhile, 600to 1000 mg testosterone will be primary driving bulk, fullness, and the estrogenic environment. ←This part is important on Tren. Test acts as a foundation, not a replacement. These roles are complementary, not mutually exclusive.

I don't know who that gentleman is you speak of, I don't really get out much. Haha

But I'm confident very much so in saying he's wrong.

Edit: Here is a tidbit of dosing from various cattle studies. These are different in method of delivery. They are slow. So why are humans taking doses above what was given to 1000lb animals which returned incredible results? There was a gent here not long ago running 1g Tren, wondering why his kidneys were failing. Jeez I don't know fella. Haha

Revalor-G / TBA/E40 mg TBA + 8 mg E2
Estradiol. Used early in feeding/growth phase

Merck Animal Health USA
Revalor-S120 mg TBA + 24 mg E2 Estradiol
Mid-level finishing implant

DailyMed
Revalor-200 or Revalor-XS
200 mg TBA + 20–40 mg E2 Estradiol
High dose / long release
DailyMed +1

Synovex® one variants
50–200 mg TBA + 7–28 mg E2 Estradiol
Multiple dose strengths exist

Zoetis
Finaplix-H
200 mg TBA (no estradiol)
Pure trenbolone implant (without estrogen)

you continue to be the goat, thank you bro.

the youtuber was "Kurt Havens" btw.

im going to cite this post over and over again when people defend huge tren cycles. if 200mg is enough for a cow, its enough for me.

 

[BALLISTIC]

you continue to be the goat, thank you bro.

the youtuber was "Kurt Havens" btw.

im going to cite this post over and over again when people defend huge tren cycles. if 200mg is enough for a cow, its enough for me.

That's it man, and all that I'm trying to do here on Meso, is get gents to look things up that have credible research points to establish conscious thought. I like helping so that dudes can move forward intelligently.

I think the greatest downfall to PEDS and enhancement is the continuous repeat of dead rhetoric.

This dude in the photo image was my first baby sitter. My Dad would have to split to work and such leaving my brother and I alone at a really young age. Chris lived down the street at the time and was a scrawny dude, but cool guy. Now look at him and vegan.

We can break the rules over and over or learn from them.