Which has a longer 1/2 life Nandrolone decanoate or Nandrolone undecylate. I'm finding conflicting data.

Cherokee

Banned
What’s the truth? I’ve found info stating:

Nandrolone decanoate has an absorption half life of 6 days
Intramuscular: 6–12 days
Nandrolone undecylate half-life of the drug (around 18 days)


Yet, the Profile on MESO’s website states:
Dynabolon (nandrolone undecanoate) It has a shorter life in the body than Deca Durabolin.
 
Well, I guess it depends on what Half life you are talking about.
Decanoate has a longer "half life" vs Undecylenate but a shorter "Terminal Half-life"


Screen Shot 2021-12-13 at 12.41.45 PM.png
 
Terminal Half-life Vs Half life. Whats the difference?

Which one is more important, if you don't want to pin as often?
They’re interchangeable man, your getting Into the science that’s only applicable on paper - not reality.

just pick one and pin it every 10 days your fine
 
They’re interchangeable man, your getting Into the science that’s only applicable on paper - not reality.

just pick one and pin it every 10 days your fine
The difference seems like it's almost double. 7.5 VS 14

I would rather have a question that can't be answered, than an answer I can't question.
 
Undecanoate ester has 11 carbons, decanoate has 10. The longer ester has the longer half-life.

The two terms are NOT interchangeable. Terminal half-life is the amount of time required for a drug's plasma concentration to decrease by half during the terminal phase (the terminal region of a pharmacokinetic curve in which drug concentration can be estimated using first-order kinetics) and is dependent on both the rate of distribution of the drug into tissues and on the rate of elimination (elimination half-life).
 
Undecanoate ester has 11 carbons, decanoate has 10. The longer ester has the longer half-life.

The two terms are NOT interchangeable. Terminal half-life is the amount of time required for a drug's plasma concentration to decrease by half during the terminal phase (the terminal region of a pharmacokinetic curve in which drug concentration can be estimated using first-order kinetics) and is dependent on both the rate of distribution of the drug into tissues and on the rate of elimination (elimination half-life).
I was referring to undecylate not Undecanoate. Or are the the same? Thank you for the explanation.
 
Undecanoate ester has 11 carbons, decanoate has 10. The longer ester has the longer half-life.

The two terms are NOT interchangeable. Terminal half-life is the amount of time required for a drug's plasma concentration to decrease by half during the terminal phase (the terminal region of a pharmacokinetic curve in which drug concentration can be estimated using first-order kinetics) and is dependent on both the rate of distribution of the drug into tissues and on the rate of elimination (elimination half-life).


To make it simple for us simpletons...when we want to determine how long it will take for a drug to leave our system, for example, do we use half-life or terminal half-life?
 
That graph I posted show they have different half life's. So is that graph I posted incorrect?
The chart you posted lists undecylenate and undecanoate. Undecylenate and undecylate are 2 different things. The "en" portion in undecylenate denotes the presence of a double bond (an alkENe), this case at the end of the aliphatic tail. This double bond shortens the half-life since the carbon next to it is more easily oxidized and cleaved due to the presence of the double bond.
 
To make it simple for us simpletons...when we want to determine how long it will take for a drug to leave our system, for example, do we use half-life or terminal half-life?
Half-life, not terminal half-life. Terminal half-life is really unimportant to the vast majority of us.
 
Back
Top