Why does Primo kill my libido instantly, even on Tren

This happened to me on my most recent cycle. I wasn't on tren at that time though. As far as a mechanism is concerned, I think it's because primo mimics DHT in the body. Some guys' libido seems to respond well to (or is at least unaffected by) DHT derivatives, but others need real DHT to maintain libido. If primo is competitively binding to whatever proteins that are in charge of maintaining libido instead of DHT, then libido can be affected.

Anavar has always crushed my libido after the first week or 2. I can't speak to masteron, simply because I have not used it enough to give any meaningful insight. I have never used DHB.

This is similar to finasteride syndrome, in which the drug inhibits DHT production. Some guys suffer decreased libido, whereas others have no issues.

While on 350 mg/week tren ace, primo lowers - but does not crush - my libido. The most I've done (as far as I can recall, I don't have my notes in front of me) while on this dose of tren was 280 mg/week of primo enanthate.
I remember taking anavar for couple weeks now and stopped because it made me feel a zombie from day 1
 
this kinda knowledge is gold for some of us. Primo annihilates my sex drive, now i know to avoid anavar aswell, some of us are sensitive to our DHT receptors being occupied by non DHT apparently @GreenAmine good contribution about the orals

personally ill never run primo again. but its good to know that Tbol and anadrol are good choices for those of us inclined
So individual man, primo has no negatives on my libido at all, anavar makes me feel like a depressed zombie by the end of day 1, I had to stop it after 2 weeks dudnt feel like the low mood was worth it. Though it really started to increase cosmetics
 
How much is this on pg/ml? I can't find the range you posted. Also, is there a chance to blame it on very low SHBG? Some feel the same with single digit have some issues. Man this thing scares me enough now, after 3 months on just T i'm about to add primo in 2-3 weeks along with the T as i'm going for a cut. Libido is through the roof now (errections quality though is worse, i can't explain why) but i haven't seen my gf for 8 days and i'm busting a nut 2-3 times a day, that horny feeling is fucking awesome and i can't think it might go away since i add the primo.
Its in mnol/l

29.6 mnol test is 853 pg/ml
Estrogen is 48 pg/ ml i think
 
Yeah bud looks like there is more then only e2 with libido on primo
This is my blood on 300 test 200 primo

Test 29.6
Oestradiol 0.16
Shbg 7.5

So e2 isn't crushed but i have no libido

when you have crushed e2 on primo maybe a little ment per day like 5mg will work
Bro your test should be way higher than 29.6 nmol. Mine is 33 nmol on 95mg test enanthate for my trt
 
I wouldn't underestimate the E2 effects of primo. Primo crushed my E2 within 12 hours of pinning it. Handfuls of dbol and test p couldn't even save me. It was awful. 2 weeks of horrible joint pain and horrible mental effects while waiting for it to clear.
Wow that’s v extreme did you get bloods straight after pinning it? How much primo did you do in that one shot and how long had you been on test and how much of that?
 
Wow that’s v extreme did you get bloods straight after pinning it? How much primo did you do in that one shot and how long had you been on test and how much of that?
No bloods unfortunately, but felt likely classic low E2 feeling. Joints felt incredible dry and achy. Mood was awful also.

Just the first 100mg shot of primo on top of my usual 200mg of test that I had already been on and feeling fine on for a long time.
 
How come every time I introduce primo into my cycle it kills my libido/erections immediately.

Before you say it crashed my E2, there's no way it crashed my E2 in less than 24 hours while I'm running 1250mg testosterone

Scenario: My libido is raging, I'm beating my meat 3-4 times a day and still not satisfied, running tren and test both high. Now I pin Primo and I shit you not the very next day I can't even get a boner and I have zero interest in sex

I compiled screenshots of people experiencing the same thing. Apparently it's a thing that happens with DHB aswell? And DHB is very similar to Primo, no?

View attachment 158400
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I’m 7 weeks into DHB and even when it started to peak it caused me no libido issues lol running it alongside NPP and high Test. I then added in 300mg Mast Prop to simmer down a gyno flair up and regardless of how good it makes me feel, I have to drop it because of how much it has intensified my libido. Too much thinking with the wrong brain and that’s not how I operate, can't even take my 5mg Tadalafil preworkout or else I’m damn near fully bricked.
 
Man im glad i found this thread. First time using primo with my trt 200 test with 100 primo. Pinned 50 mg primo then the day after had no interest in sex and couldnt get hard wtf.
 
I Using 350 test 250 primo
Libido isn't good but not really sides of low estrogen but my old gyno is shrinking for almost 50% and it was there for years

Going to try test primo 3:1 ratio

Ik did 2:1 and 1:1 both kills libido
If 3:1 isn't working primo isn't my steroid and i will try mast
 
I Using 350 test 250 primo
Libido isn't good but not really sides of low estrogen but my old gyno is shrinking for almost 50% and it was there for years

Going to try test primo 3:1 ratio

Ik did 2:1 and 1:1 both kills libido
If 3:1 isn't working primo isn't my steroid and i will try mast
Proviron is also a great DHT to use, just gives me a little bit of acne
 
I never understand why somebody will take proviron
For libido while on trt dose maybe. Although if used along with higher test while running another dht like mast or primo it will probably nuke shbg. It seems it has limited applications.
 
How do you have time to beat off 4 times a day my guy?
Tf you doin at work mane u one of em pussies who doesn’t just go to beat off in the bathroom n get paid off the company dime? Cmon now I really assumed people were better than this I’m very disappointed especially considering your username mane smh
 
The only thing I have noticed is I'm running test Primo and anavar .I took an avavar 25mg right before sex yesterday. I had already had 50 mg for the day I thought it would give me some extra pumps LOL and my girlfriend doesn't know about it she said she thought I had taken a Viagra or something cuz I was just murdering her poon. She came twice already and I couldn't cum for like a long time.... she kept telling me to cum on her tits or her face and it took me an extra 30 minutes.
That’s cos u gotta bust inside mane, dw if she don’t want u to just lmk I can come over n bust on her tits for you ;) after that bukkake I’m sure she will let u just bust inside it’s wayyy better
 
No bloods unfortunately, but felt likely classic low E2 feeling. Joints felt incredible dry and achy. Mood was awful also.

Just the first 100mg shot of primo on top of my usual 200mg of test that I had already been on and feeling fine on for a long time.
I’d really like to see you get bloods using primo again, but obviously take 500mg test for a month get bloods, then add just 100mg primo and get bloods 2 days later.

Hell I want to do this now! Even though primo really ages my face to an unacceptable level, 100mg isn’t going to hurt my skin. I’d like to see it’s AI affect on me on paper.

I’d encourage all the meso primo users to do this. We can get some great data on this steroid.

In the 70s this AI effect of primo must have been priceless. There’s no longer a ceiling on how much test n dbol you can take. Maybe 4 times as much providing primo doesn’t give you prostate & skin n hair issues
 
No bloods unfortunately, but felt likely classic low E2 feeling. Joints felt incredible dry and achy. Mood was awful also.

Just the first 100mg shot of primo on top of my usual 200mg of test that I had already been on and feeling fine on for a long time.
I got this as well, coach had me do 300 test, 500 primo. The next day I was incredibly dehydrated, anxious, messed up joints. I continued that protocol for a few weeks before needing to change it. E2 came back at around 16 (in range) but I would not deny the issues. I was EXTREMELY dehydrated, primo tends to cause this for me when it’s too high in relation to testosterone. It may not be the way that it raises or lowers estrogen, but possibly another aspect of somehow modulating estrogen?
 

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