Determined to understand the dosing of Depo-T I created a absorption calculator in Excel that calculates the absorption levels of Depo-T over time and graphs the daily concentrations of Active T in the blood. I did this so I could see the difference between the various dosing possibilities. Id post the graphs but I dont have a location to host the charts so Im just including the summary numbers. It's interesting to see how doubling the first dose helps stablize T-levels very quickly as opposed to just starting the regular dose.
Note: These values are only after treatment on a dose for at least 45 days so that ramp up values are not evaluated. These calculations assume a Depo-T half-life of 8 days as published.
On 100mg every 7 days we have:
18.251 - Maximum Daily Concentration (mg)
14.244 - Average Daily Active Concentration (mg)
9.951 - Minimum Daily Concentration (mg)
8.300 - Change in Concentrations During Cycle (mg)
On 200mg every 14 days we have:
23.622 - Maximum Daily Concentration (mg)
14.257 - Average Daily Active Concentration (mg)
7.599 - Minimum Daily Concentration (mg)
16.023 - Change in Concentrations During Cycle (mg)
On 150mg every 7 days we have:
27.377 - Maximum Daily Concentration (mg)
21.366 - Average Daily Active Concentration (mg)
14.927 - Minimum Daily Concentration (mg)
12.449 - Change in Concentrations During Cycle (mg)
On 300mg every 14 days we have:
35.433 - Maximum Daily Concentration (mg)
21.385 - Average Daily Active Concentration (mg)
11.398 - Minimum Daily Concentration (mg)
24.035 - Change in Concentrations During Cycle (mg)
On 200mg every 7 days we have:
36.502 - Maximum Daily Concentration (mg)
28.488 - Average Daily Active Concentration (mg)
19.903 - Minimum Daily Concentration (mg)
16.599 - Change in Concentrations During Cycle (mg)
On 400mg every 14 days we have:
47.244 - Maximum Daily Concentration (mg)
28.514 - Average Daily Active Concentration (mg)
15.197 - Minimum Daily Concentration (mg)
32.047 - Change in Concentrations During Cycle (mg)
Just thought Id post this. Im still analyzing various dosing amounts and schedules but its interesting that my current dose of 400mg every 14 days has a swing in concentrations twice as much as 200mg every 7 days, which makes sense.
Scott
Note: These values are only after treatment on a dose for at least 45 days so that ramp up values are not evaluated. These calculations assume a Depo-T half-life of 8 days as published.
On 100mg every 7 days we have:
18.251 - Maximum Daily Concentration (mg)
14.244 - Average Daily Active Concentration (mg)
9.951 - Minimum Daily Concentration (mg)
8.300 - Change in Concentrations During Cycle (mg)
On 200mg every 14 days we have:
23.622 - Maximum Daily Concentration (mg)
14.257 - Average Daily Active Concentration (mg)
7.599 - Minimum Daily Concentration (mg)
16.023 - Change in Concentrations During Cycle (mg)
On 150mg every 7 days we have:
27.377 - Maximum Daily Concentration (mg)
21.366 - Average Daily Active Concentration (mg)
14.927 - Minimum Daily Concentration (mg)
12.449 - Change in Concentrations During Cycle (mg)
On 300mg every 14 days we have:
35.433 - Maximum Daily Concentration (mg)
21.385 - Average Daily Active Concentration (mg)
11.398 - Minimum Daily Concentration (mg)
24.035 - Change in Concentrations During Cycle (mg)
On 200mg every 7 days we have:
36.502 - Maximum Daily Concentration (mg)
28.488 - Average Daily Active Concentration (mg)
19.903 - Minimum Daily Concentration (mg)
16.599 - Change in Concentrations During Cycle (mg)
On 400mg every 14 days we have:
47.244 - Maximum Daily Concentration (mg)
28.514 - Average Daily Active Concentration (mg)
15.197 - Minimum Daily Concentration (mg)
32.047 - Change in Concentrations During Cycle (mg)
Just thought Id post this. Im still analyzing various dosing amounts and schedules but its interesting that my current dose of 400mg every 14 days has a swing in concentrations twice as much as 200mg every 7 days, which makes sense.
Scott