Galacticbass
New Member
Interesting reads. Prescribed TRT and this thread has answered a lot of questions. Thank you.
Does this apply to Hormone Replacement Therapy? IE bringing testosterone back up to normal levels. Recently started taking HRT, as prescribed by a doctor, and tested regularly.While many PED users have other risk factors for ASCVD, unfortunately because of their putative effects on thrombogenesis, high dose AAS may be all that's required for vascular occlusion.
To that end prophylactic ASA may be a reasonable means of lowering thrombogenic risk.
From the study he attached . . .Does this apply to Hormone Replacement Therapy? IE bringing testosterone back up to normal levels. Recently started taking HRT, as prescribed by a doctor, and tested regularly.
Thank you for posting.From the study he attached . . .
Quote:
Male hormones and protein-assimilating hormone therapy in 27 hypoplastic anemia patients resulted in three cases of sagittal sinus thrombosis [82]. A case of acute myocardial infarction was reported in a non-athlete who inadvertently received therapeutic intravenous testosterone for hypogonadism [83,84], as well as a case of stroke secondary to testosterone therapy in a 21-year-old hypogonadal man [84]. A meta-analysis of 27 placebocontrolled studies detected an increased risk of cardiovascular events in men who received testosterone therapy, compared to placebo [85]. A population-based case-control trial has recently reported an increased risk of venous thromboembolism after testosterone therapy, peaking within six months after the treatment cessation [86]. On the other hand, there are data indicating that low serum testosterone concentrations are also associated with increased cardiovascular risk and mortality, and that testosterone replacement therapy may have beneficial effects [87,88]. Several recent systematic reviews and meta-analyses did not find clear evidence of increased risk for cardiovascular events in men with testosterone prescription [89,90]. Moreover, low plasma androgen levels in hypogonadal patients have been linked to deficient platelet function, explaining the presence of hemorrhagic diathesis observed in this population [91,92].
Does this apply to Hormone Replacement Therapy? IE bringing testosterone back up to normal levels. Recently started taking HRT, as prescribed by a doctor, and tested regularly.
Thank you very much. Cheers to you sir.Although not zero, whether male or female, the risk of legitimate HRT related thrombogenesis is relatively low.
Males are considered low risk for HRT related thrombogenic complications IF they have no history of arterio-venous occlusion and no more than ONE of the following (smoking, age >65, cholesterol, HTN, DM, Morbid obesity)Thank you very much. Cheers to you sir.
I would speak with your cardiac specialist and see what they say.Would TRT be a no no for me? My Total t 202 free 36.1
Meeting with a surgeon on 9/4
I need
Subaortic Stenosis (SubAS) Resection
Left Ventricular Outflow Tract (LVOT) Enlargement
Aortic Valve Replacement (mechanical)
Aortic Root Replacement
Right Ventricular to Pulmonary Artery (RV-PA) Conduit Replacement.
History
Subclavian Flap Repair for coarctation of the aorta as an infant.
Aortic Valvotomy and Subaortic Stenosis Resection (1987).
Repeat Subaortic Stenosis Resection and Aortic Valve Repair (1991).
Ross Procedure with 23 mm Pulmonary Homograft (1998).
Pulmonary Valve Replacement (PVR) with a 25 mm bioprosthetic valve and Ascending Aorta Graft Repair with a 26 mm Ultramax Double Velour graft (2009).
Thank you.
I do plan to discuss it with my surgeon. My cardiologist was just dismissive when i brought it up initially and told me with a surgery on the horizon its probably not a good idea. I think hes biased against it. Depending on what the Endo and surgeon say, I will likely ask the cardiologist team officially where that one can't just dismiss it offhand because his wife is an endo who hates people using it for performance.I would speak with your cardiac specialist and see what they say.
I have a lengthy cardiac history myself(much different then yours) and I didn't go on trt until my cardiologist and electrophysiologt both signed off on it.
Ask your docs and proceed from there. Best of luck with your heart.
It could just be that your cardiologist does not want complicating factors. He knows what he is doing and how to have good outcomes, and he does not want another variable introduced this late in the game.I do plan to discuss it with my surgeon. My cardiologist was just dismissive when i brought it up initially and told me with a surgery on the horizon its probably not a good idea. I think hes biased against it. Depending on what the Endo and surgeon say, I will likely ask the cardiologist team officially where that one can't just dismiss it offhand because his wife is an endo who hates people using it for performance.
Could be, but I felt like his attitude was roiling his eyes lol and how he phrased it. Im totally cool waiting till after the surgery as well if thats the only issue.It could just be that your cardiologist does not want complicating factors. He knows what he is doing and how to have good outcomes, and he does not want another variable introduced this late in the game.