Compounded Tirz has been vanquished. UGL likely next. Stock up.

Ghoul

Member
The following is my opinion as to what's just ahead of us in the UGL based drug landscape. It's based on my close observation of the political and business movements likely to affect this market. As with every opinion, feel free to take or discard my advice as you see fit.


Eli Lily has finally succeeded in putting a stake in the heart of compounded copies of their $1000/mo drug. With the amount of money on the line, expect them to turn their attention to Chinese knockoffs.

While Tirz (and all peptides/protein therapeutics except growth hormone) are not controlled substances, legal to purchase from many legitimate chemical suppliers, they are not legal to sell for human use.

One element in the upcoming De Minimus small package crackdown is a requirement that every product intended for consumer use is required to comply with all relevant regulations, including those from the FDA, and the seller must provide documentation proving it.

The TLDR is this requirement is sufficient for customs to stop the importation of pharma compounds being sent to individuals. Anyone who buys India pharma regularly knows the FDA can seize any med, regardless of whether it's a controlled substance or not. You can be sure that Eli and Novo are already lobbying hard to ensure these tools are employed in the new tightening customs regime.

Like all contraband in high demand, it'll still find a way in, but expect it to be much more expensive.

For those who rely on these meds, it would be wise to stock up while it's inexpensive and plentiful, to ride out any potential interruption in supply.

If you can get a prescription, even if your insurance doesn't cover it (and many more do now so it's worth rechecking), because once you drop below the qualification BMI, you'll never be able to get a prescrip. Once on it, you'll be able get "maintenance" prescription renewals even if you're normal weight.

You don't have to fill those prescriptions if you choose to keep using UGL, but it's a good backup in case you can't get UGL. Remember, these *hormones* are intended for indefinite use, and those coming off overwhelmingly return to baseline weight.
 
Alright, so after crunching the numbers, my Tirz stash is looking pretty legendary:
15 vials at 20 mg (300 mg)
20 vials at 30 mg (600 mg)
10 vials at 50 mg (500 mg)
Total of 1400 mg.

That means I’ll be set for:
280 weeks at 5 mg/week
186.7 weeks at 7.5 mg/week
140 weeks at 10 mg/week
112 weeks at 12.5 mg/week
93.3 weeks at 15 mg/week.

Basically, I’m stocked up for every dosing scenario, unless I decide to start sharing… which I won’t.
Let me know when you've got 3 grams ;)
 
Let me know when you've got 3 grams ;)
Honestly, I don’t even need that much, especially since I’m planning to give Reta a spin in the future. I’m not in it for weight loss- this is all about those sweet, beneficial effects, particularly tackling insulin resistance. But yeah, three grams? That’s a whole lot of Tirz. Feels like you’re prepping for an apocalypse
 
Alright, so after crunching the numbers, my Tirz stash is looking pretty legendary:
15 vials at 20 mg (300 mg)
20 vials at 30 mg (600 mg)
10 vials at 50 mg (500 mg)
Total of 1400 mg.

That means I’ll be set for:
280 weeks at 5 mg/week
186.7 weeks at 7.5 mg/week
140 weeks at 10 mg/week
112 weeks at 12.5 mg/week
93.3 weeks at 15 mg/week.

Basically, I’m stocked up for every dosing scenario, unless I decide to start sharing… which I won’t.

Let me know when you've got 3 grams ;)
I have 3,700mg. Well, my Wife does. I switched to Reta long ago
 
One major element of immunogenicity is the variation in immune strength among individuals. For instance, patients with AIDS are unlikely to experience immunogenicity problems with protein drugs, compared to a healthy person.

High T reduces the chances of immunogenicity:


So anything that reduces immune response is likely to lower the chances of developing immunity to peptides.
So assuming that I buy the finest grade gutter-Reta from Wuhan Oriental Ostarine & Peptide Supply (WOOPS) and manage to turn my immune system into a raging monster with cross-reactive neutralizing antibodies targeting nGLP-1… do you think I’d be able to get my insurance to cover Orforglipron to treat the autoimmune disorder? Pron is an oral small molecule and probably wouldn’t be affected by these antibodies, so I think Pron will be pretty popular (mostly because people prefer oral). But unlike all of the weight losers paying cash, I could have an insurance medical need for Pron.
 
So assuming that I buy the finest grade gutter-Reta from Wuhan Oriental Ostarine & Peptide Supply (WOOPS) and manage to turn my immune system into a raging monster with cross-reactive neutralizing antibodies targeting nGLP-1… do you think I’d be able to get my insurance to cover Orforglipron to treat the autoimmune disorder? Pron is an oral small molecule and probably wouldn’t be affected by these antibodies, so I think Pron will be pretty popular (mostly because people prefer oral). But unlike all of the weight losers paying cash, I could have an insurance medical need for Pron.
Fake news, dude who wrote the article looks like he needs some testosterone and is just jelly.
 
I read the article that they would stop allowing compound pharmacies to sell tirz as of yesterday but all of my friends that are on it from compound pharmacies are still getting it.
Some of the compounding pharmacies are attempting some very transparent “workarounds” to try to stay in the game.

“This patient’s physician prescribed 2.51mg/week of tirz and that’s not a commercially available dosage. 2.50mg/week didn’t work for them they had crippling side effects but 2.51mg/week is perfect. Thank god we compounding pharmacists can supply custom dosages!”

Eli’s lawyers are gonna shut that down pretty quick.
 
Some of the compounding pharmacies are attempting some very transparent “workarounds” to try to stay in the game.

“This patient’s physician prescribed 2.51mg/week of tirz and that’s not a commercially available dosage. 2.50mg/week didn’t work for them they had crippling side effects but 2.51mg/week is perfect. Thank god we compounding pharmacists can supply custom dosages!”

Eli’s lawyers are gonna shut that down pretty quick.
A more common workaround is adding B12 or glycine to the tirzepatide to make it a "unique" formulation that can still be manufactured/sold by the compounding pharmacies. We'll see how long this will hold up after the presumed upcoming lawsuits.
 
Anyone consider grabbing the raw apis? Yes pretty expensive for a drop but it would in theory let you be ready for a shortage if you grab 5 grams of it..... Just save up. Grab and save money too. Considering Grabing a bit. I did the math. Huge cost savings for a bigger supply than premade.
 
Anyone consider grabbing the raw apis? Yes pretty expensive for a drop but it would in theory let you be ready for a shortage if you grab 5 grams of it..... Just save up. Grab and save money too. Considering Grabing a bit. I did the math. Huge cost savings for a bigger supply than premade.
Home brewing tirz from raw is nothing like test. It's not feasible.
 
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